Complete in vitro method! Affinity maturation to obtain antibodies with higher binding capacity.
The "ADLib System" is an antibody acquisition platform based on cell surface display, and it is a proprietary technology of Kaiom Biosciences, Inc. It features "speed" since it does not require animal immunization, and it creates "a unique antibody library that utilizes the functions inherent to cells" to generate antibody diversity. Additionally, it is also possible to perform "unique and simple affinity maturation." 【Features】 ■ Approximately 7 weeks until the sequence report of selected clones ■ Effective against difficult antigens such as antibodies that are less likely to induce immune responses, low molecular weight compounds, and immune tolerance ■ Improvement of affinity for antibodies obtained from sources other than this system, such as those derived from hybridomas, is also possible *For more details, please download the PDF or feel free to contact us.
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【Antibody Production Flow】 ■ Use of a proprietary antibody library ■ ADLib selection and ELISA screening ■ Sequence analysis of antibody gene variable regions (light chain, heavy chain) ■ Affinity maturation of selected clones *Optional *For more details, please download the PDF or feel free to contact us.
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From research and development of pharmaceuticals to manufacturing and diagnostics, Merck is working to solve various challenges in life sciences in collaboration with the global science community. Merck's products include over 300,000 items, ranging from laboratory pure and ultra-pure water systems to gene editing tools for drug manufacturing, antibodies, cell lines, and end-to-end systems. To realize promising research more quickly and safely, we closely collaborate with customers in academia, the biotechnology industry, and the pharmaceutical industry. Please feel free to contact us for inquiries about our products or if you are interested in raw material supply. Here is the Merck ultra-pure and pure water systems webpage → https://www.merckmillipore.com/LW Here is the Merck life science reagents, raw materials, and analysis webpage → https://www.sigmaaldrich.com/JP/ja