The Sievers TOC meter for cleaning validation is effective in various situations such as lab, at-line, and online, depending on the application.
TOC and conductivity are important analytical items that support cleaning validation, cleaning verification, and cleaning monitoring. TOC measurements can be performed in response to user requests in various settings, including laboratories, manufacturing sites (at-line), and online (final rinse water monitoring from CIP).
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- Three models of TOC Analyzer Sievers M9 Lab model: Suitable for analyzing rinse/swab samples in the laboratory. Online model: Can be directly connected to CIP for automatic analysis of rinse samples. Portable model: Suitable for quick measurement results and equipment release in the manufacturing area. - Advantages of each model Lab model: Increases efficiency and productivity, reduces error rates from environmental sources, shortens measurement time with turbo mode (from 2 minutes to 4 seconds). Online model: No need for sample transportation, real-time release, improves productivity and measurement time, quick updates with turbo mode. Portable model: Monitors cleaning cycles of multiple equipment, enables rapid troubleshooting, effective for PAT (Process Analytical Technology). - Validation support package Utilizing a validation support package for cleaning validation simplifies implementation. The package includes guidance, examples, worksheets, templates, and sample protocols. It details content aimed at streamlining cleaning validation. For more details, please refer to the fact sheet.
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Applications/Examples of results
Cleaning validation of pharmaceuticals
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Since our establishment in 1967, we have been dedicated to the development and dissemination of water quality measurement devices that anyone can use quickly, easily, and with high precision. In today's world, where the effective use of water, a limited resource, is required alongside environmental conservation, we aim to be a total solution provider that responds to all water environments by utilizing our water quality measurement devices, technology, and services. Furthermore, leveraging the latest technology and years of know-how, we are committed to delivering user-friendly and reliable water quality measurement devices more affordably, quickly, and widely.