Tohoku Univ. Technology:Method for predicting of sensitivity to chemotherapy for colorectal cancer: T14-026
Capable of selecting anti EGFR antibody-sensitive/resistant patient from Ras wild-type group
Anti-EGFR treatment for colorectal cancer is effective for patients without RAS mutation. However, response rate of the treatment is no more than 30%. This inventor analyzed the DNA methylation status of tissue samples from patients treated by anti-EGFR antibody. The result showed that highly methylated colorectal cancer (HMCC) has higher drug resistance than low methylated colorectal cancer (LMCC).
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The revenue generated from technology transfer is reinvested as new research funding for universities and researchers, and is utilized to create further research outcomes. To ensure the smooth operation of this cycle, known as the "Intellectual Creation Cycle," we will vigorously promote technology transfer. The types of seeds we handle include patents, know-how, databases, and programs. We have established a collaborative framework by signing basic technology transfer agreements with the following universities (as of June 1, 2025): Tohoku University, Hirosaki University, Iwate University, Akita University, Fukushima University, Yamagata University, Tohoku Gakuin University, Iwate Medical University, Fukushima Medical University, Aizu University, Miyagi University, Hokkaido University, Muroran Institute of Technology, and Showa Medical University.
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