Activation and proliferation of CAR-T cells targeting the proliferation of CD8+ cells aimed at obtaining high stem cell-like characteristics and therapeutic effects.
NanoSpark STEM-T T Cell Activator is a reagent available for immediate culture for the in vitro activation and proliferation of human T cells. NanoSpark STEM-T T Cell Activator is a self-assembling protein nanoparticle with anti-CD3 antibodies and anti-CD28 antibodies bound to its surface through high-affinity non-covalent interactions. The unique biophysical composition of the anti-CD3 and anti-CD28 antibodies present on the surface of the STEM-T nanoparticles induces strong primary and co-stimulatory signals that specifically activate and proliferate T cells, promoting the production of stem cell-like CD8+ T cells.
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Related Applications ■ T Cells | CAR-T Cells ■ Research and Manufacturing of Cancer Immunotherapy Related Process Steps ■ Activation and Proliferation of T Cells
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Sartorius Stedim, established in 2007 through the merger of the German company Sartorius, founded in 1870, and the French company Stedim, is a pioneer in "Single-Use Technology (SUT)." As a company capable of providing comprehensive technical support to the pharmaceutical and biotechnology industries, its cutting-edge technology is highly regarded worldwide in the fields of scientific instruments and biotechnology.
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