Tohoku Univ. Technology ：Functional Pearl-like Multilayer Nanomaterials：T25-050
Efficient and Eco-friendly Mass Production via Yeast and Koji Mold Fermentation
This invention presents a new platform for creating organic-CaCO₃ composite materials with pearl-like multilayer nanostructures using a bio-manufacturing process involving yeast and koji mold. Building on prior research into the bio-mineralization of Pteria penguin pearls, the inventors have successfully expressed the related proteins and enzymes in yeast to produce highly controlled multilayer CaCO₃ crystals. High-Performance Materials ：By optimizing the expression of matrix proteins and enzymes, the crystal structure and material properties can be precisely controlled. Sustainability ：The fermentation-based production process enables large-scale manufacturing with minimal environmental impact and low cost.
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The revenue generated from technology transfer is reinvested as new research funding for universities and researchers, and is utilized to create further research outcomes. To ensure the smooth operation of this cycle, known as the "Intellectual Creation Cycle," we will vigorously promote technology transfer. The types of seeds we handle include patents, know-how, databases, and programs. We have established a collaborative framework by signing basic technology transfer agreements with the following universities (as of June 1, 2025): Tohoku University, Hirosaki University, Iwate University, Akita University, Fukushima University, Yamagata University, Tohoku Gakuin University, Iwate Medical University, Fukushima Medical University, Aizu University, Miyagi University, Hokkaido University, Muroran Institute of Technology, and Showa Medical University.
