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Functional material "Katsuo Elastin"

Functional material "Katsuo Elastin"

Developing a method for producing functional materials using fish as raw materials!

【Functional Display Food Compatible】Marine Elastic Component "Elastin" Elastin is a type of protein that is widely distributed in tissues requiring elasticity, such as skin, blood vessels, and ligaments, and it functions to provide elasticity. 【List of Efficacy】 ■ Improves skin elasticity and sagging ■ Alleviates pain and discomfort in knee joints (ligaments) ■ Improves vascular elasticity ■ Suppresses breast sagging and provides lifting effect ■ Improves lung function 【Features】 ■ Uses main ingredients with a history of consumption ■ Low odor and easily soluble in water ■ Abundant efficacy and safety data obtained

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Functional material "Hishi extract"

Functional material "Hishi extract"

Anti-glycation and AGEs decomposition: Polyphenol 'Hishi extract'

"Hishiekisu" is a plant-derived polyphenol carefully selected from 791 samples, possessing high anti-glycation activity and AGE decomposition activity. AGEs (advanced glycation end products) are substances generated in the body when sugars react with proteins, and they are known to be causes of aging and diseases, such as decreased skin elasticity, skin yellowing, and complications of diabetes. 【List of Efficacy】 ■ Improvement of skin yellowing ■ Improvement of skin elasticity and sagging ■ Confirmation of suppression of blood sugar level rise ■ Improvement of lipid metabolism disorders 【Features】 ■ Use of main ingredients with a history of safe consumption ■ Acquisition of abundant efficacy and safety data

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Hishi extract: LDL & adiponectin

Hishi extract: LDL & adiponectin

By adding Hishi extract, we confirmed a concentration-dependent inhibition of GML production in LDL!

Glycation of LDL has been reported to interfere with the normal metabolism of cholesterol and is involved in thrombus formation, which contributes to the progression of atherosclerosis. When human serum-derived LDL was glycated with glyoxal, the amount of CML produced was measured, and it was confirmed that the addition of Hishi extract inhibited the generation of GML in LDL in a concentration-dependent manner. Additionally, it was confirmed that the addition of Hishi extract promoted cell differentiation and increased the concentration of adiponectin within the cells. 【Glycation of LDL and the Effects of Hishi Extract】 ■ Inhibitory effect of Hishi extract on LDL glycation ■ Reduction of LDL-C through Hishi extract intake *For more details, please refer to the PDF document or feel free to contact us.

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Effects of elastin on the lungs

Effects of elastin on the lungs

Actively engage in maintaining and improving athletic performance! Introducing the effects of elastin on the lungs.

Here is an introduction to the effects of elastin on the lungs. Elastin is an important protein for maintaining the normal function of the lungs, and it makes up about 20% of the elastin fibers in the lungs. The lung structure becomes more fragile with aging, which is closely related to qualitative changes in elastin and collagen, accompanied by a decrease in elastic recoil. As lung function declines, vital capacity and gas exchange ability decrease, leading to shortness of breath and difficulties during exercise. However, tests on human lung fibroblasts using PG showed that bonito elastin has an activating effect on lung cells. 【Cell Test Results】 ■ Maintenance and improvement of exercise performance ■ Activation of lung cells 【Animal Test Results】 ■ Shortened recovery time for blood oxygen saturation after exercise in aging mice ■ Promoting healing effects on lung tissue in lung injury model mice *For more details, please refer to the PDF document or feel free to contact us.

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Elastin's effect on blood vessels

Elastin's effect on blood vessels

Blood vessels become flexible! Clinical trial results showed improvements in vascular elasticity and endothelial function.

I will introduce the effects of elastin on blood vessels. Elastin is distributed in tissues that require elasticity and extensibility, with elastin fibers making up about 50% of the aorta. Elastin in blood vessels decreases and ruptures with aging, becoming one of the causes of arteriosclerosis. In human clinical trials, there were improvements in vascular elasticity and endothelial function. [Results of Human Clinical Trials] ■ Vascular elasticity significantly improved ■ Vascular dilation significantly improved *For more details, please refer to the PDF document or feel free to contact us.

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Ascofilan HS: GLP-1 secretion promoting effect and diet support.

Ascofilan HS: GLP-1 secretion promoting effect and diet support.

Diet support mediated by the gut-derived hormone GLP-1 is suggested! The secretion-promoting effect was confirmed in cell tests!

We would like to introduce the GLP-1 secretion promoting effect of Ascofilan HS. Ascofilan HS has been confirmed to promote GLP-1 production in the intestines through cell tests. GLP-1 is a hormone produced by intestinal cells that acts on the hypothalamus, stomach, and pancreas, and the following three effects are expected: - Appetite suppression - Prolongation of food retention time in the stomach - Promotion of insulin production From the above, the intake of Ascofilan HS is expected to support weight loss. Additionally, tests using cells and clinical trials in humans have also been conducted. [Cell Tests] - Promotion of GLP-1 production from intestinal-derived cells [Clinical Trials] - Potential to suppress postprandial blood sugar spikes and improve HbA1c levels - Confirmation of weight loss before and after intake in monitoring tests *For more details, please refer to the PDF document or feel free to contact us.

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Elastin: Vascular functionality indication (maintenance of vascular flexibility)

Elastin: Vascular functionality indication (maintenance of vascular flexibility)

Vascular functional indication obtained! Elastin peptides derived from bonito help maintain the flexibility of blood vessels, which decreases with aging!

The intake of 75mg/day of bonito elastin has received the following functional claims. ■ Functional Health Claims "It has been reported that elastin peptides derived from bonito help maintain the flexibility of blood vessels (the degree of expansion of blood vessels after being constricted), which decreases with aging." "It has been reported that elastin peptides derived from bonito help maintain the elasticity of blood vessels (the degree of expansion of blood vessels after being constricted), which decreases with aging." In human clinical trials, improvements in endothelial function and vascular elasticity have been confirmed, making it recommended for addressing symptoms such as cold extremities and fatigue caused by vascular issues. Furthermore, bonito elastin is the only material that can be labeled as "bonito vascular component." This makes it easy to associate with the image that "because it is a vascular component, it is good for blood vessels!" 【Elastin Functional Effects】 ● Improvement of endothelial function ● Improvement of vascular elasticity We provide support for the notification of the above health claims. *For more details, please refer to the PDF document or feel free to contact us.

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Functional material "Ascophyllan HS"

Functional material "Ascophyllan HS"

Infection prevention and immune activation: Seaweed-derived polysaccharide 'Ascofyllan HS'

"Ascofilan HS" is a functional food ingredient rich in the seaweed-derived polysaccharide "Ascofilan," which has properties for preventing infections and enhancing immunity. It is extracted from the seaweed Ascophyllum nodosum, which grows naturally along the North Atlantic coast, particularly in Nordic regions. This extract has a low odor, is easily soluble in water, and has low viscosity. 【List of Efficacy】 ■ Improvement of immune function (immunostimulatory effect) ■ Prevention of pneumonia ■ Prevention of viral infections (HIV virus) ■ Suppression of blood sugar level increase (GLP-1) ■ Anti-cancer (anti-tumor) effect 【Features】 ■ Uses raw materials with a history of safe consumption ■ Low odor, easily soluble in water, and low stickiness ■ Abundant efficacy and safety data obtained

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