reagent Product List and Ranking from 111 Manufacturers, Suppliers and Companies | IPROS GMS

LipidBrick Cell Ready

Lipid-based delivery solutions for ex vivo gene-edited cell therapy.

LipidBrick Cell Ready is an advanced non-viral delivery system using pre-prepared lipid-based nanoparticles. This system is optimized for efficient nucleic acid delivery to various human primary cells, including T cells, NK cells, dendritic cells, and CD34+ hematopoietic stem cells. *For more details, please click on "Download PDF" below. *If you would like a sample, please contact us through "Inquire About Product" below.

Tocotrienol/Tocopherol/Paraffin reagent

We support the development of reagents for functional testing of food and cosmetics.

We have developed products derived from rice bran, including α-tocotrienol, γ-tocotrienol, α-tocopherol, δ-tocotrienol from palm, and paraffin (from rice bran). To conduct animal and human trials for the development of functional food labeling products, we have set the purity of tocotrienols to 98% in relation to the total amount of vitamin E, while keeping the product purity around 65% (with other components derived from rice bran oil) to achieve a low price. 【Features】 ■ Non-GMO (non-genetically modified) domestic rice bran-derived products ■ Providing affordable high-purity products in gram units for use in cell and animal testing ■ Adoption of manufacturing technology that considers environmental impact and safety (using only ethanol as a solvent, reducing environmental burden by 95%) ⇒ Contributing to SDGs *For more details, please download the PDF or feel free to contact us.

Watanabe Chemical Industry Co., Ltd. Company Profile

Everything is for our customers! We strive for usability from the perspective of researchers.

Founded in 1845 as Watanabe Jurodo, our company started as a drug wholesaler. After changing our name to Watanabe Chemical Industries, we transitioned from manufacturing and selling general industrial chemicals and food additives to specializing in the production and sale of amino acid and peptide synthesis reagents. As the third category of pharmaceuticals following low molecular weight drugs and antibody drugs, medium molecular weight drugs are gaining attention, particularly peptide drugs, especially cyclic peptides, which are attracting significant expectations and interest. In light of these developments, our company offers approximately 3,000 peptide synthesis reagents, primarily focusing on Fmoc amino acids and Boc amino acids, and we are committed to supporting your drug discovery research. 【Business Activities】 ■ Manufacturing and sales of peptide synthesis reagents and amino acid derivatives *For more details, please refer to the PDF document or feel free to contact us.

Dipeptide drinker "ADC LINKER"

Useful for research on antibody-drug conjugates! It is possible to selectively deliver drugs to target cells.

"ADC LINKER" is a dipeptide linker used as a component of antibody-drug conjugates. When it binds to and is taken up by cells expressing the antigen recognized by the antibody, hydrolysis occurs between Cit-pAB by cathepsin B inside the cell. The drug that is bound is then released. As a result, it allows for selective action of the drug on the target cells. Please feel free to contact us if you have any inquiries. 【Features】 ■ Useful for research on antibody-drug conjugates ■ When it binds to and is taken up by cells expressing the antigen recognized by the antibody, hydrolysis occurs between Cit-pAB by cathepsin B inside the cell ■ The drug that is bound is released *For more details, please refer to the PDF materials or feel free to contact us.

Trapping reagent

We manufacture and sell four types of trapping reagents that can be used for pharmacokinetic studies and toxicity studies.

These trapping reagents can be used for the detection and analysis of reactive metabolites that may arise during the metabolic processes of drug candidate compounds. ◆R00846 CysGlu-Dan Traditionally, Dansyl-GSH (dGSH) has been used in trapping tests for electrophilic reactive metabolites generated by CYP oxidation; however, Dansyl-GSH was unable to detect "hard" electrophilic reactive metabolites such as aldehydes. CysGlu-Dan, like Dansyl-GSH, can react with "soft" electrophilic reactive metabolites such as quinones and epoxides, as well as with "hard" electrophilic reactive metabolites, allowing for the sensitive detection of a broader range of reactive metabolites. ◆R00845 Dap-Dan This reagent can trap and detect reactive 1-O-acyl glucuronides generated during the glucuronidation process, as well as aldehydes produced through rearrangement. ◆R00847 Cys-Dan This reagent can trap and detect reactive acyl-CoA generated during the metabolic processes of fatty acids. These trapping reagents were developed by a group led by Professor Tomoyuki Oe at the Faculty of Pharmacy, Keio University.

Exosome Research Reagent Catalog Ver. 4

A research tool for exosomes in one book!

Exosomes are membrane vesicles with a diameter of 30-100 nm that are released from various cells. It has been revealed that exosomes have the function of transferring nucleic acids such as mRNA and microRNA, as well as proteins, to distant cells, and they are gaining attention as communication tools in intercellular information transfer and as biomarkers in various diseases, including cancer.

Influenza virus-related reagents

Sino Biological's influenza virus research reagents

The influenza virus is an RNA virus that causes acute respiratory diseases and outbreaks in human populations due to its strong infectivity. According to the WHO, influenza results in approximately 1 billion infections and about 290,000 to 650,000 deaths worldwide each year. Vaccination is the most effective strategy to prevent influenza virus infection and its severe complications. However, the influenza virus is prone to mutation, and the circulating strains vary from year to year. Each year, vaccine manufacturers develop and produce influenza vaccines based on the strains recommended by the WHO. Our company provides comprehensive influenza vaccine development services and production solutions to vaccine manufacturers. We offer a wide range of research reagents for influenza viruses, including influenza vaccine antigens, antibody pairs, neutralizing antibodies, and kits. Additionally, we provide high-quality technical services such as kit development, antigen expression, and antibody development. These products and services are suitable for various vaccine development scenarios, including screening of vaccine candidate strains, preparation of virus seed batches, evaluation of vaccine safety and immunogenicity, and assessment of vaccine protective effects.

Research Reagent Online Store "ChemCupid"

Posted inventory compound data of suppliers with a high supply rate (10 million items).

"ChemCupid" is a web-based compound search database that contains data on over 20 million compounds. You can search using various methods such as structural formulas, NSCode, CAS, MDL, and Name. It is also possible to import code lists and SDFiles for bulk searches. Furthermore, search results can be downloaded in SDFile/Excel format, and you can easily request quotes or place orders via the web. 【Features】 ■ Over 20 million listed compounds ■ Abundant search methods ■ Publicly available pricing, stock status, and supplier IDs ■ Cart functionality implemented ■ Easy quote requests for desired compounds via the web, etc. *For more details, please download the PDF or feel free to contact us.

TargetMol Chemicals Inc. Company Profile

Strict quality control and complete data! We provide one-stop solutions in the field of drug discovery.

Our company is a high-tech enterprise headquartered in Boston, USA. We own the TargetMol brand, which provides products and services for chemical and bio research. Since our establishment, we have offered a wide range of high-quality chemical substances to pharmaceutical companies, biotechnology firms, academic institutions, and other research organizations around the world. Our biochemical reagents cover more than 10 research fields, including anti-cancer, anti-viral, cardiovascular, and immune system, as well as over 20 signaling pathways and more than 300 research targets. [Business Description] ■ Provision of products and services for chemical and bio research *For more details, please refer to the PDF document or feel free to contact us.

Gyrolab Human Cytokine Kit Reagent

Minimal manual operation! Suitable for use throughout regulated research development.

The "Gyrolab Human Cytokine Kit Reagent" is a product that efficiently measures cytokine biomarkers in human serum when used. Through automation, it generates 96 data points within 90 minutes without manual intervention. The wide dynamic range minimizes the need for dilutions. As a result, experiments for spike recovery and dilution linearity are simplified, reducing variability due to errors and speeding up the workflow. 【Features】 ■ Automated assay ■ Robust, reproducible, and reliable data ■ High sensitivity and wide dynamic range ■ High throughput *For more details, please refer to the PDF document or feel free to contact us.

For hygiene management dirt testing! Blood reaction liquid.

It can also be used for quality control in the packaging industry and medical-related companies! It is easy to determine whether stains such as smudges are bloodstains.

We will introduce the observation of the luminol reaction using our "Experiment-kun Chemical No. 6 Blood Reaction Liquid Kit." ~ Various companies use it as a quality control testing reagent to determine whether stains on packaging materials, tableware, medical devices, clothing, etc., are "blood." ~ Add 3cc of 1N sodium hydroxide solution and 0.1g of luminol into a bottle with a dropper, close the lid, and gently shake to mix. Then, add 3cc (the entire amount) of 3% hydrogen peroxide to the solution you just made, close the lid, and gently shake to mix. After that, drop a few drops of the completed solution into a beaker or petri dish, add a few grains of red blood salt, and if the luminol reaction (glowing bluish-white) is confirmed at the moment of addition, the blood reaction liquid (luminol reaction liquid) is complete. *For more details, please refer to the PDF document or feel free to contact us.*

Omniscript RT Kit

Reverse transcriptase | Ideal for applications using very small amounts of RNA

■Reverse transcription reaction using 50 ng to 2 μg of RNA per reaction ■Ideal for applications using very small amounts of RNA, such as single-cell RT-PCR and biopsy LMD samples *For more details, please download the PDF or feel free to contact us.*

AllTaq Master Mix/PCR Core Kits

Advanced hot start PCR, reliable results anytime.

This product is based on QIAGEN's proprietary hot-start PCR technology, offering many advantages to users. AllTaq significantly reduces the time spent on PCR optimization, minimizes operational errors, and allows for visual confirmation. Additionally, it supports the sensitivity to detect a single molecule and accommodates GC-rich targets and long chain length targets (up to 9 kb). 【Features】 ■ Streamlined PCR ■ Experience the flexibility of AllTaq ■ Prevention of reagent omission ■ Avoidance of artifacts and primer dimers ■ Reliable detection of even a single molecule ■ High product stability *For more details, please download the PDF or feel free to contact us.

Bovine Serum Albumin (BSA) Fraction V

IgG-free, for biochemistry and molecular biology! The process is conducted in a closed system.

"Bovine Serum Albumin (BSA) Fraction V" is recommended as a blocking and stabilizing reagent in all antibody-mediated detection systems. Available in IgG-free, sourced from New Zealand in sizes of 10g, 50g, 200g, and 500g. The purification of albumin uses extensive heat shock/diafiltration methods. Additionally, the process is conducted in a closed system. 【Product Overview】 ■Molecular Weight (M): ~66000g/mol ■Storage Temperature: +4℃ ■WGK1 ■CAS Number: 9048-46-8 ■EG-Nr. 232-936-2 ※Other variations are also available. Biotin-free, fatty acid-free, protease-free. Origin: USA, Europe. For cell biology, protein analysis, and molecular biology, etc. ※For more details, please refer to the PDF document or feel free to contact us.

Eosin B (C.I. 45400)

For Hematoxylin-Eosin (H&E) staining! Dissolve in water or ethanol at 0.5 to 2.0%.

We would like to introduce our product, 'Eosin B (C.I. 45400).' It is used for Hematoxylin-Eosin (H&E) staining, similar to Eosin Y used in plasma staining. It dissolves in water or ethanol at a concentration of 0.5 to 2.0%. We offer pack sizes of 10g, 25g, and 50g, and the packaging is glass. Please feel free to consult us when placing an order. [Product Overview (Excerpt)] ■ Pack sizes: 10g, 25g, 50g ■ Packaging: Glass ■ 4',5'-Dibromo-2',7'-dinitrofluorescein disodium salt, Eosin Scarlet, Eosin Blueish ■ Chemical formula: C20H6Br2N2Na2O9 *For more details, please refer to the PDF document or feel free to contact us.

Information on imported reagents from Carl Roth.

The "imported reagents" from Karl Roth, a German company founded in 1879, which are used by many researchers in the field of international research, can be purchased from us!

The German manufacturer of scientific instruments and reagents, 'Carl Roth', continues to be favored by many researchers in the field of international collaborative research. To bring this global standard to Japan, we started sales in 2017 as the official distributor in Japan. If you are looking for imported reagents from Carl Roth, please feel free to consult us. <Examples of imported reagents> - Blocking reagent 'ROTI Block' - Gelatinous agent for microbial culture 'GELRITE' - Astra Blue FM (C.I. 48048) - Bovine Serum Albumin (BSA) Fraction V <Biotin-free> - Malt extract, etc...

n-Butyllithium

When storing, keep it under inert gas! Avoid contact with water and air.

"Normal butyllithium" is a mixture with aliphatic hydrocarbon solvents. Therefore, it falls under the category of hazardous materials, Class 4, Category 1, non-water-soluble petroleum products. Additionally, butyllithium itself has a property of reacting violently with water. We recommend using it within three months. When using, please refer to the SDS and handle it after thorough investigation. 【Properties】 ■Molecular weight: 64.06 ■Solubility: Easily mixes with aliphatic hydrocarbons ■Stability: Stable below room temperature under an inert gas atmosphere *For more details, please refer to the PDF document or feel free to contact us.

Research-use HISCL VEGF reagent

After setting the sample in the dedicated device, the measurement will be completed in 17 minutes!

We would like to introduce our "Research HISCL VEGF Reagent" available for your use. After setting the sample in the dedicated device, the measurement is completed in 17 minutes. This method employs a two-step sandwich chemiluminescent enzyme immunoassay. Additionally, we also offer the "Research HISCL PEDF Reagent," which is intended for the measurement of human PEDF in cell culture supernatants. 【Measurement Range】 ■VEGF: 15-70,000 pg/mL ■PEDF: 0.5-4,200 ng/mL *For more details, please download the catalog or feel free to contact us.

Human adipose stem cell culture supernatant purified extract (freeze-dried)

Reproducible biological functions mediated by secreted factors from stem cells in vitro and in vivo!

The 'Human Adipose Stem Cell Culture Supernatant Purified Extract (Freeze-Dried)' is a research reagent standardized for HGF (Hepatocyte Growth Factor). It is an extract of human adipose stem cell supernatant made with low toxicity through Telebio's unique technology. It can reproduce biological functions mediated by the secretory factors of stem cells both in vitro and in vivo. Two specifications are offered, with '500TBU' expected to promote higher cell proliferation. 【120TBU Specifications】 ■ Specification: 120TBU ■ Product Code: RFV2A ■ Quality Assurance Period: 3 years after manufacture ■ Classification: Research Reagent *For more details, please download the PDF or feel free to contact us.

Human Papillomavirus Luminescent Detection Reagent

Detecting HPV16 with a smartphone!

Luminescent Detection Reagent for Human Papillomavirus: Dozyme (HPV16) is a luminescent detection reagent for Human Papillomavirus type 16 (HPV16) using DNA origami technology. This product estimates the number of HPV16 in a sample based on the genetic sequence that codes for the L1 capsid protein of HPV16. Measurements can be easily performed using a smartphone or a general-purpose luminescence measurement device, offering higher specificity compared to traditional electrophoresis methods and providing rapid results. Additionally, it allows for cost-effective measurement of target DNA compared to real-time PCR.

Modification of woody biomass using genome editing technology.

Keywords: Plants, Biomass, Genes, Genome Editing, Substance Production

Plants absorb carbon dioxide from the atmosphere to grow, serving as biomass that contributes to decarbonization. A portion of the absorbed carbon dioxide is utilized in the cell walls. In the xylem, which is composed of vessel elements and fiber cells, a thickened secondary cell wall is formed inside the normal cell wall. Since the majority of the biomass of trees, which have the largest biomass above ground, consists of xylem, it can be said that the secondary cell wall is the substance of tree biomass. Furthermore, the secondary cell wall is primarily composed of polymer compounds such as cellulose and lignin, which are also attracting attention as materials for bioethanol and biopolymers. The formation of the secondary cell wall involves many genes. We have identified key genes that control the entire process of secondary cell wall formation and have elucidated their molecular functions. Utilizing the insights gained, we are also working on creating useful plants for lignocellulosic biomass utilization by employing genome editing technologies to modify specific gene information.

Scoring of atopic dermatitis model using BioSta AD

We will introduce the scoring of an atopic dermatitis model using BioSta AD.

In the atopic dermatitis model using BioSta AD, after destroying the skin barrier with 4% SDS, the product is applied to the dorsal and auricular areas of the mice twice a week at a dosage of 100 mg/mouse. The induction period is approximately 3 weeks (totaling 6 applications). Ultimately, a total of 600 mg of the product will be applied. In this model, symptoms begin to appear from weeks 1 to 2 after application, with an incidence rate of about 80% observed by weeks 3 to 4. 【Scoring】 [Redness and bleeding (observing redness and bleeding symptoms on the back)] ○0: Asymptomatic; no redness or bleeding symptoms observed on the back ○1: Mild; localized redness observed on the back, with no bleeding associated with continuous scratching ○2: Moderate; scattered redness observed on the back, with no bleeding associated with continuous scratching ○3: Severe; widespread redness observed on the back, with bleeding associated with continuous scratching For more details, please contact us or download the catalog.

【Feature 1】Seven characteristics of monoclonal antibody production contract services.

The success rate over the past three years boasts over 90% and has been adopted by many pharmaceutical companies.

1. Strategic Selection By using control antigens for strategic selection, it is possible to produce antibodies with special specificities, such as those that recognize the presence or absence of post-translational modifications, or antibodies that recognize common parts of homologous proteins. 2. Production of Antibodies Difficult to Obtain through Animal Immunization Since it does not rely on animal immunization, it is possible to produce antibodies against human or mouse antigens regardless of immune tolerance. Additionally, it is possible to produce antibodies against toxic antigens or immunosuppressive substances. Furthermore, since there is no antigen presentation step, it is also possible to produce antibodies that recognize natural three-dimensional structures. 3. Delivery of Candidate Antibodies in Just 7 Weeks Thanks to automated screening of antibody libraries, automated sequencing, and automated ELISA analysis, the time required from receipt of the antigen to delivery of candidate antibodies (up to 5) is just 7 weeks. For points 4 to 7, please refer to the seven features of the monoclonal antibody production contract service in Feature 2. *For more details, please refer to the PDF document or feel free to contact us.

Monoclonal Antibody Production Contract Service Prices

The price is based on standard antibody production costs. A precise estimate will be provided after consultation for each project, considering the most efficient process.

Antibody Production Pricing Standard Antibody Production = ¥1,800,000 per antigen Provision of 1 to 5 candidate antibodies (200μg each) from which the customer can select the final antibody, provided at 1mg (Myc-His tagged, ELISA positive). Additional Sequencing = ¥50,000 per 10 clones Additional sequencing for the same antigen. *The standard price includes sequencing for 10 clones. Additional Candidate Antibodies = ¥50,000 per candidate antibody Additional candidate antibodies for customer confirmation against the same antigen (200μg each). *The standard price includes delivery of up to 5 clones. Additional Final Antibody Production = ¥70,000 per 1mg Additional production of final antibodies for the same antigen simultaneously. *The standard price includes delivery of 1 clone (1mg). *For more details, please refer to the PDF document or feel free to contact us.

Monoclonal antibody production contract option service

Format conversion

Format Conversion The antibodies obtained through the Antibody Artisan's contract services come with various optional services. If an Fc region is required, we can convert the candidate antibody's Fab into full-length human, human-mouse chimeric, or human-rat chimeric forms, and deliver purified IgG molecules within 10 weeks. After cloning the genes for the VH and VL regions along with the desired constant region into a vector, we simultaneously introduce the light chain and heavy chain vectors into mammalian cells for expression. For more details, please also refer to the selection of antibody formats in the service flow. For pricing, please inquire for confirmation. *This is an optional service for antibodies produced through the Antibody Artisan service. *This menu is not applicable to antibodies you already possess. *For more details, please refer to the PDF materials or feel free to contact us.

Monoclonal antibody production contract option service

Production of two types of antibodies (sandwich pair) with different antigenic determinants (epitopes).

Production of two types of antibodies (sandwich pair) with different antigen determinants (epitopes). The antibodies obtained through the Antibody Artisan's contract services come with various optional services. The sandwich method serves as the foundation for many research and diagnostic assay systems. At Antibody Artisan, we provide methods to discover the best-matching antibody pairs. For pricing, please inquire for confirmation. *This is an optional service for antibodies produced by Antibody Artisan. *The menu is not applicable to antibodies you already possess. *For more details, please refer to the PDF materials or feel free to contact us.

FITC-labeled diluted antibody 'JTC FR017R'

Diluted antibodies adjusted for tissue staining!

"JTC FR017R" is a C3c complement extracted from human serum and reacts with human C1q complement. This antibody is prepared for tissue staining and cannot be stored frozen. Please use a light-protected humid box and perform staining at room temperature for 30 to 60 minutes or overnight at 4°C. 【Features】 ■ Extracted from human serum ■ For tissue staining ■ Cannot be stored frozen ■ Pre-diluted *For more details, please refer to the catalog or feel free to contact us.

Monkeypox Virus Stock

Support for the evaluation of nucleic acid tests! Helps identify random or systematic errors.

Bairoquest Inc. provides a wide range of services to all researchers active at the forefront of life sciences. The 'Monkeypox Virus (Recombinant) Stock' is designed to detect a specific part of the Monkeypox virus genome and aims to support the evaluation of nucleic acid tests. This product helps laboratories monitor variations in testing, performance between lots of test kits, and operator variability, aiding in the identification of random or systematic errors. 【Features】 ■ Designed to detect a specific part of the Monkeypox virus genome ■ Aims to support the evaluation of nucleic acid tests ■ Laboratories can monitor variations in testing and operator variability ■ Helps identify random or systematic errors ■ Unit size: 1mL *For more details, please refer to the PDF document or feel free to contact us.

Reagents suitable for the accurate detection of CAR-T cells.

CAR-T cell detection products useful for the development, quality control, and clinical monitoring of CAR-T cells.

We would like to introduce the CAR-T cell detection products offered by Cytoart. The generation of CAR-T cells requires the transfection of CAR genes into T cells via viral or non-viral systems. The CAR-positive T cells that express CAR on their membrane have the ability to recognize and damage target cells, making the detection of CAR-positive T cells a crucial step in the quality control of CAR-T cell therapy, as well as an important criterion for managing clinical doses, process monitoring, and diagnostic assistance. Cytoart's antibody development platform focuses on targeting the scFV region on CAR-T cells. Advantages of using scFV for target detection in CAR-T cell therapy: - High specificity: Ensures accurate target binding and reduces off-target complications. - Sensitivity: The detection of targets using scFV allows for real-time monitoring of the activity and distribution of low levels of CAR-T cells in samples. - Versatility: scFV target detection can be applied to various types of research related to CAR-T cells.

RAT-NMP reagent