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Service Introduction: "Custom Oligonucleotide Synthesis Service"

Total support from basic research to clinical development! We provide oligonucleotides with optimal specifications.

At Ajinomoto Bio-Pharma Services Gene Design, we provide a variety of nucleic acid drug seeds such as siRNA, aptamers, antisense, decoys, miRNA, and CpG-ODN, tailored to optimal specifications for cell assays, in vivo experiments, in vitro diagnostic pharmaceuticals, and clinical trial GMP-compliant products. We also offer fluorescent labeling, such as Alexa modifications, and detection probes like LNA oligos at reasonable prices to support your basic research. 【Features】 - Extensive experience with cross-linked nucleic acids such as LNA and BNA, various modifications like 2’-OMe RNA and 2’-F RNA, and peptide, PEG, and ligand terminal additions. - Process development and analytical method development with an eye toward scale-up. - Experience in examining and validating standard testing methods. - Conducting stability tests necessary for GLP studies and clinical development. For more details, please contact us or download the catalog.

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  • Contract manufacturing

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miRNA mimic / S-TuD

We offer double-stranded RNA developed based on the results obtained from collaborative research!

We offer double-stranded RNA "miRNA mimic" with chemical modifications on the passenger strand and double-stranded RNA "S-TuD" primarily composed of 2’-O-Methyl RNA. The "miRNA mimic" allows you to observe the activity of the mature miRNA itself by inactivating the passenger strand. The "S-TuD" specifically binds to the Micro RNA Binding Site (MBS) of the RISC complexed mature miRNA and strongly inhibits miRNA activity even at low concentrations. 【Features】 ■ miRNA mimic - Double-stranded RNA with chemical modifications on the passenger strand - Enables observation of the activity of the mature miRNA itself - Product developed based on results obtained from collaborative research ■ S-TuD - Double-stranded RNA primarily composed of 2’-O-Methyl RNA - Strongly inhibits miRNA activity even at low concentrations - Negative control sequences are also available *For more details, please refer to the external link page or feel free to contact us.

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