Process model library (reaction, crystallization, wet and dry grinding, spray drying, wet and dry granulation, blending, and tablet compression, etc.)
gPROMS Formulated Products is equipped with a library of process models for operations such as reactions, crystallization, wet and dry milling, spray drying, wet and dry granulation, blending, and tablet compression.
In case studies applied to pharmaceutical processes, it enables consistent performance analysis of the entire system from active pharmaceutical ingredient (API) manufacturing through formulation processes to oral absorption risk analysis.
■ Solution crystallization analysis
■ Solid-liquid and solid-gas separation, classification, and granulation process analysis
■ Oral absorption analysis
This product was developed with the cooperation of major pharmaceutical companies in Europe and the United States. By using mathematical models of raw materials, unit operations, and product performance, it allows for formulation design aimed at optimizing pharmaceuticals and their manufacturing. It enables faster screening of new formulation candidates against quality attributes, including in vivo performance and manufacturability.
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