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  6. Modeling tool for solid and powder processes 'gFORMULATE'

Modeling tool for solid and powder processes 'gFORMULATE'

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gPROMS FormulatedProducts 1.6.0 

last updated:Mar 05, 2021

シーメンス株式会社  gPROMS ポートフォリオ
シーメンス株式会社 gPROMS ポートフォリオ
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Process model library (reaction, crystallization, wet and dry grinding, spray drying, wet and dry granulation, blending, and tablet compression, etc.)

gPROMS Formulated Products is equipped with a library of process models for operations such as reactions, crystallization, wet and dry milling, spray drying, wet and dry granulation, blending, and tablet compression. In case studies applied to pharmaceutical processes, it enables consistent performance analysis of the entire system from active pharmaceutical ingredient (API) manufacturing through formulation processes to oral absorption risk analysis. ■ Solution crystallization analysis ■ Solid-liquid and solid-gas separation, classification, and granulation process analysis ■ Oral absorption analysis This product was developed with the cooperation of major pharmaceutical companies in Europe and the United States. By using mathematical models of raw materials, unit operations, and product performance, it allows for formulation design aimed at optimizing pharmaceuticals and their manufacturing. It enables faster screening of new formulation candidates against quality attributes, including in vivo performance and manufacturability.

    simulatorOther analysesAnalysis Services
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Modeling tool for solid and powder processes 'gFORMULATE'

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  • Related Link - https://www.psenterprise.com/products/gproms/formu…

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basic information

gPROMS FormulatedProducts allows you to select the necessary components for the basic platform. The functionalities for Simulation (steady state and dynamic) and GSA (Global System Analysis) are standard features. <Optional Features> * Flowsheet Construction & Modification * Custom Modelling * Optimisation: Process optimization considerations * Parameter Estimation * gPROMS High Performance Computing * Hybrid Multizonal gPROMS/CFD Interface * gSAFT – SAFT equation of state * Multiflash/Multiflash DIPPR and more <Optional Libraries> ■ Solution crystallization analysis ■ Solid-liquid and solid-gas separation, classification, granulation process analysis ■ Oral absorption analysis

Price information

For your reference: 3 million to 8 million (per year) We accept contracts on a monthly basis.

Delivery Time

P2

Applications/Examples of results

In the case applied to the pharmaceutical process, it is possible to achieve consistent overall system performance from active pharmaceutical ingredient manufacturing through the formulation process to risk analysis of oral absorption. PSE regularly conducts free training sessions regarding this product. Anyone is welcome to participate. Since the release of gPROMS FormulatedProducts 1.3 in December 2018, a food manufacturing process and mining process library have been added. The food manufacturing process library is the result of collaborative research with world-leading food nutrition organizations, and it includes models for membrane filtration, thermal processing, falling film evaporators, and multi-stage spray drying. In the recent version upgrade (gPROMS FormulatedProducts 1.6), a reaction calorimeter model and an HPLC model have been added. If you would like materials on software application cases, please contact us.

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Modeling tool for solid and powder processes: 'gPROMS FormulatedProducts'

Modeling tool for solid and powder processes: 'gPROMS FormulatedProducts'

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Company Overview Siemens Process Systems Engineering

Company Overview Siemens Process Systems Engineering

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Technical Documentation: Optimal Design and Control of Continuous Processes

Technical Documentation: Optimal Design and Control of Continuous Processes

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Technical Data: gPROMS Formulated Products Crystallization/Solid Handling

Technical Data: gPROMS Formulated Products Crystallization/Solid Handling

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Oral Absorption Analysis Tool gPROMS FormulatedProducts

Oral Absorption Analysis Tool gPROMS FormulatedProducts

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【Technical Information】Latest Model-Based Approaches for Building IVIVC of Poorly Soluble Drugs for Oral Absorption

【Technical Information】Latest Model-Based Approaches for Building IVIVC of Poorly Soluble Drugs for Oral Absorption

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gPROMS Academic License

gPROMS Academic License

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Technical Documentation Oral Absorption Analysis and Formulation Design Case Study gPROMS FormulatedProducts

Technical Documentation Oral Absorption Analysis and Formulation Design Case Study gPROMS FormulatedProducts

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gPROMS Property Package

gPROMS Property Package

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gPROMS Food

gPROMS Food

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Spray Drying Spray Dryer Model

Spray Drying Spray Dryer Model

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Introduction to Pharmaceutical Modeling Integration Software

Introduction to Pharmaceutical Modeling Integration Software

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Spray Drying Spray Dryer Model

Spray Drying Spray Dryer Model

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Virtual Manufacturing Pharmaceutical Simulation Software

Virtual Manufacturing Pharmaceutical Simulation Software

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Digital Twin of Continuous Direct Hit Process (AstraZeneca)

Digital Twin of Continuous Direct Hit Process (AstraZeneca)

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Bioprocess Digital Twin

Bioprocess Digital Twin

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Proposal for gPROMS for the Food, Beverage, and Fast-Moving Consumer Goods (FMCG) Industry

Proposal for gPROMS for the Food, Beverage, and Fast-Moving Consumer Goods (FMCG) Industry

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User case) Food, Beverage, and Fast-Moving Consumer Goods (FMCG) industry

User case) Food, Beverage, and Fast-Moving Consumer Goods (FMCG) industry

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Digital Twin of Bioreactor - Towards QbD Development...

Digital Twin of Bioreactor - Towards QbD Development...

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Examples of Accelerating SDGs Promotion through DX: Powdered Milk Production Process Using Spray Dryer (Danone)

Examples of Accelerating SDGs Promotion through DX: Powdered Milk Production Process Using Spray Dryer (Danone)

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Company information

シーメンス株式会社

シーメンス株式会社 gPROMS ポートフォリオ

software

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Founded in 1997 by the gPROMS development team at Imperial College London, PSE became part of the Siemens Group in 2019 and has been providing products and services in Japan as Siemens Corporation since 2023. gPROMS features a powerful equation-based computation engine that differs from traditional simulators, allowing for seamless handling of both steady-state and dynamic simulations. This enables the effective scaling up of models adjusted with experimental data from batch processing for the design and operational optimization of continuous processing plants. With gPROMS's excellent capabilities in custom modeling, parameter estimation, and optimization, it is possible to quickly build optimal manufacturing processes, resolve issues, and achieve optimization.

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