Powder process simulation software
Powder Process Analysis Software gPROMS FormulatedProducts
Visualize continuous processes! For improving quality and reviewing production costs in active pharmaceutical ingredient manufacturing and formulation processes. *We provide support from demo tests to utilization follow-up.
This is a modeling tool developed in collaboration with a U.S. mega-pharma company. Recently, the pharmaceutical industry has been transitioning from batch production to continuous production, and it is being used for process design and control system considerations. It is a model library of gPROMS FormulatedProducts. In continuous production processes, advanced quality management (PAT, QbD, RTRT) becomes possible, as well as the ability to handle small-batch, multi-product production, but at the same time, high-precision process modeling technology becomes essential. If you have any inquiries such as "I want to reduce plant construction costs," "I want to increase production volume at existing plants," or "I want to improve product quality (particle size distribution)," please feel free to contact us! 【Features】 ■ Capable of steady-state and dynamic (dynamic) simulation ■ Easily handles multiple recycle streams ■ Allows for optimization considerations of plant design and operation methods ■ Can identify and estimate process equipment performance from test data ■ Provides graphical representation of batch plant operating procedures ■ Can be linked with crystallization process analysis libraries ■ Can be linked with oral absorption analysis libraries *For more details about the product, please download the PDF from the link below.
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basic information
By modeling and simulating the solid handling process, the following effects are expected: 1. Advanced quality monitoring and management (PAT, QbD, RTRT) 2. Reduction in development and manufacturing time, and space-saving of equipment 3. Adaptation to small-batch, diverse production 4. Ease of scale-up and scale-down 5. Improvement in product quality (particle size distribution) 6. Increased production volume in existing plants 7. Support for the formulation of flexible operating guidelines in response to production demands 8. Identification of individual processes and characteristics of solid handling equipment
Price information
Please contact us (short-term contracts available). You can choose the license period (from monthly to yearly).
Delivery Time
P3
※This is the delivery date after the licensing agreement. If you have any other questions, please feel free to contact us.
Applications/Examples of results
Characteristics of Continuous Production Processes (1) Reduction of human errors and avoidance of stockout risks through early detection of quality defects (2) Reduction of manufacturing costs and ease of changing or relocating manufacturing sites (3) Application to generic pharmaceuticals and personalized medicine (4) Reduction of costs related to manufacturing and storage, etc.
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Company information
Founded in 1997 by the gPROMS development team at Imperial College London, PSE became part of the Siemens Group in 2019 and has been providing products and services in Japan as Siemens Corporation since 2023. gPROMS features a powerful equation-based computation engine that differs from traditional simulators, allowing for seamless handling of both steady-state and dynamic simulations. This enables the effective scaling up of models adjusted with experimental data from batch processing for the design and operational optimization of continuous processing plants. With gPROMS's excellent capabilities in custom modeling, parameter estimation, and optimization, it is possible to quickly build optimal manufacturing processes, resolve issues, and achieve optimization.
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