Powder Process Simulation Software 'gFORMULATE'
Powder Process Analysis Software gPROMS FormulatedProducts
Visualize the manufacturing process for pharmaceuticals and food! For improving quality and reviewing production costs in active ingredient manufacturing and formulation processes. *Demo tests are currently being conducted.
This is a modeling tool developed in collaboration with a U.S. mega-pharma company. Recently, the pharmaceutical industry has been transitioning from batch to continuous production, and it is being used for process design and control system considerations. It is a model library of gPROMS FormulatedProducts. In continuous production processes, advanced quality management (PAT, QbD, RTRT) and the ability to accommodate small-batch, diverse production become possible, but at the same time, high-precision process modeling technology becomes essential. If you want to "reduce plant construction costs," "increase production volume at existing plants," or "improve product quality (particle size distribution)," please feel free to contact us! You can watch the video on YouTube: https://youtu.be/AJZcgI-r2Ik
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basic information
**Features** - Capable of steady-state and dynamic (dynamic) simulation - Easily handles multiple recycling streams - Enables optimization studies for plant design and operation methods - Can identify and estimate process equipment performance from test data - Allows graphical display of batch plant operating procedures - Can interface with crystallization process analysis libraries - Can interface with oral absorption analysis libraries By conducting modeling and simulation of solid handling processes, the following effects are expected: 1. Advanced quality monitoring and management (PAT, QbD, RTRT) 2. Reduction in development and manufacturing time, and space-saving of equipment 3. Adaptation to small-batch, diverse production 4. Easy scale-up and scale-down 5. Improvement in product quality (particle size distribution) 6. Increased production volume in existing plants 7. Support for the formulation of flexible operating guidelines in response to production demands 8. Identification of individual process and solid handling equipment characteristics
Price information
Please contact us (short-term contracts available). You can choose the license period (from monthly to yearly).
Delivery Time
P4
※This is the delivery date after the license agreement. If you have any other questions, please feel free to contact us.
Applications/Examples of results
<Features of Continuous Production Process> (1) Reduction of human errors and avoidance of stockout risks through early detection of quality defects (2) Reduction of manufacturing costs and ease of changing or relocating manufacturing sites (3) Application to generic pharmaceuticals and personalized medicine (4) Reduction of costs related to manufacturing and storage, etc.
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Company information
Founded in 1997 by the gPROMS development team at Imperial College London, PSE became part of the Siemens Group in 2019 and has been providing products and services in Japan as Siemens Corporation since 2023. gPROMS features a powerful equation-based computation engine that differs from traditional simulators, allowing for seamless handling of both steady-state and dynamic simulations. This enables the effective scaling up of models adjusted with experimental data from batch processing for the design and operational optimization of continuous processing plants. With gPROMS's excellent capabilities in custom modeling, parameter estimation, and optimization, it is possible to quickly build optimal manufacturing processes, resolve issues, and achieve optimization.
