We have compiled a list of manufacturers, distributors, product information, reference prices, and rankings for HPLC columns.
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HPLC columns Product List and Ranking from 16 Manufacturers, Suppliers and Companies

Last Updated： Aggregation Period:Aug 20, 2025～Sep 16, 2025
This ranking is based on the number of page views on our site.

HPLC columns Manufacturer, Suppliers and Company Rankings

Last Updated： Aggregation Period:Aug 20, 2025～Sep 16, 2025
This ranking is based on the number of page views on our site.

  1. 関東化学株式会社 Tokyo//Chemical バイオケミカル部
  2. 東ソー Tokyo//Chemical バイオサイエンス事業部　計測分野
  3. 日本ウォーターズ（米国本社 Waters Corporation）　 Tokyo//Testing, Analysis and Measurement
  4. 4 サーモフィッシャーサイエンティフィック株式会社／Thermo Fisher Scientific K.K. Tokyo//Testing, Analysis and Measurement
  5. 5 ADSTEC Corporation Chiba//others Bio Department
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HPLC columns Product ranking

Last Updated： Aggregation Period:Aug 20, 2025～Sep 16, 2025
This ranking is based on the number of page views on our site.

  1. High Purity Silica Gel HPLC Column "Mightysil Series" 関東化学株式会社 バイオケミカル部
  2. HPLC column for sugar analysis - "CarboSep Series" ADSTEC Corporation Bio Department
  3. HPLC column 日本ウォーターズ（米国本社 Waters Corporation）　
  4. 4 HPLC column "Size Exclusion Chromatography" 東ソー バイオサイエンス事業部　計測分野
  5. 5 High-performance columns for HPLC, UHPLC, and UPLC [CORTECS] 日本ウォーターズ（米国本社 Waters Corporation）　

HPLC columns Product List

46～60 item / All 78 items

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ZORBAX Rx Reverse Phase HPLC Column

ZORBAX Rx Reverse Phase HPLC Column

Rx-C18 is recommended for separation in low pH regions! It shows excellent stability and peak shape.

The "ZORBAX Rx Reverse Phase HPLC Column" is suitable for high-throughput analysis. It shows different selectivity compared to Eclipse XDB-C18 and StableBond SB-C18 in the low pH range, and StableBond is recommended for high-temperature applications. Additionally, Rx-C18 is manufactured using dimethyl octadecyl silane and demonstrates excellent stability up to pH 9 due to the lack of end-capping. 【Features】 ■ Shows different selectivity compared to Eclipse XDB-C18 and StableBond SB-C18 in the low pH range ■ Exhibits excellent stability and peak shape in low pH applications ■ Rx-C18 is manufactured using dimethyl octadecyl silane and demonstrates excellent stability up to pH 9 due to the lack of end-capping ■ Rx-C8 is the same product as SB-C8 *For more details, please refer to the PDF document or feel free to contact us.

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ZORBAX Extend-C18

ZORBAX Extend-C18

Improvement of retention, separation ability, and peak shape in base compounds! Introducing ZORBAX reverse phase HPLC columns.

The "ZORBAX Extend-C18" utilizes a groundbreaking bidentate C18-C18 bonding technology, enabling the development of high-separation methods in high pH regions while being a silica-based column. The unique bidentate bonding and double-end capping enhance stability at high pH. It improves retention, separation capability, and peak shape for basic compounds. To extend column life, it is preferable to use triethylamine, ammonium hydroxide, or pyrrolidine as buffer solutions, while phosphate buffers are not recommended. 【Features】 - High separation efficiency and long lifespan in high pH regions (up to pH 11.5) - Improved stability at high pH due to unique bidentate bonding and double-end capping - Higher efficiency and superior peak shape compared to polymer-based columns - High sensitivity and separation for LC/MS analysis of peptides and proteins *For more details, please refer to the PDF document or feel free to contact us.

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PL Multisolvent

PL Multisolvent

Adopting silica with excellent efficiency and robustness! Eliminating the expansion and contraction of pores due to changes in solvents.

"PL Multisolvent" is a product that coats silica with a large pore volume using an innovative process involving inert polymers. The column separates low to medium molecular weight polymers in solvents such as water and tetrahydrofuran (THF) without secondary reactions. The silica backbone provides excellent resolution and eliminates degradation due to expansion during solvent transfer. 【Features】 ■ Utilizes silica with excellent efficiency and robustness ■ The silica backbone with high strength eliminates pore expansion and contraction caused by solvent changes ■ Supports high-resolution separation of polymers, additives, oligomers, and plasticizers up to 100,000 Da *For more details, please refer to the PDF document or feel free to contact us.

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HPLC column "Sunniest"

HPLC column "Sunniest"

Developing a new combined phase! A column with an unprecedented end capping.

"Sunniest C18" uses a tri-functional reagent and features end-capping based on a unique new concept, making it the only one in the world. "Sunniest" significantly suppresses the influence of residual silanol groups, allowing for a wider range of conditions without tailing of basic compounds, and enabling the optimal setting of mobile phase pH and column temperature. 【Features】 ○ Almost no influence from silanol groups ○ Superior end-capping ○ The bonding reagent also has the effect of end-capping ○ RP-AQUA is prepared for stable separation with 100% aqueous mobile phase ○ Columns are available from an inner diameter of 2.0mm to 20mm for preparative use For more details, please contact us or download the catalog.

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Core shell type column "SunShell C4-100"

Core shell type column "SunShell C4-100"

Reverse phase column for the separation of monoclonal antibodies with a pore diameter of 1000A! Utilizing core-shell particles to achieve high theoretical plate numbers!

The "SunShell C4-100" is a core-shell type column for the separation of monoclonal antibodies. SunShell columns utilize core-shell silica and a specially modified Sunniest-bonding method, achieving efficient deactivation of silanol groups while also possessing high durability. Additionally, by using core-shell particles, the theoretical plate number per pressure increases, allowing for high separation to be easily achieved even with existing HPLCs that do not have high pressure tolerance. 【Features】 ■ Uses core-shell particles to achieve a high theoretical plate number ■ Usable in both HPLC and UHPLC with low pressure and high theoretical plate number ■ Sharp peak shapes due to excellent end-capping *For more details, please download the PDF or feel free to contact us.

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The high-performance column "L-column3" proposes new possibilities for analysis.

The high-performance column "L-column3" proposes new possibilities for analysis.

Evolved further from the L-column2! Achieving both exceptional chemical durability and top-level low adsorption. An unparalleled high-performance all-around column.

The "L-column3" is a high-performance HPLC column manufactured and sold by the Chemical Evaluation and Research Institute (CERI), a general incorporated foundation. The "L-column3" features newly developed PCS silica (Perfect Chemical Stable Silica) with very high alkali resistance and enhanced durability through advanced end-capping, significantly improving the chemical durability of the packing material (acid resistance, alkali resistance), making it an all-around column. 【Features】 ■ High alkali resistance, usable from pH 1 to 12 ■ Top-class low adsorption for all types of analyses ■ The ability to freely select the pH of the eluent improves separation and peak shape ■ Stable analysis even with 100% aqueous eluents 【New Products】 ◇ High-pressure column L-column3 HP type ◇ Semi-preparative column L-column3 For more details, please download the catalog or feel free to contact us.

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HPLC Column "Reversed Phase / HILIC"

HPLC Column "Reversed Phase / HILIC"

Numerous charts are included. In addition to the characteristics of each mode, we introduce the main target substances.

This document contains information on HPLC columns for normal phase chromatography and multi-mode chromatography. In addition to the characteristics of each mode, it introduces the main target substances. Furthermore, it includes charts and tables for separation and comparison. [Contents (excerpt)] ■ Normal Phase Chromatography ■ Multi-Mode Chromatography ■ Columns for LC/MS ■ Reverse Phase Chromatography *For more details, please refer to the PDF document or feel free to contact us.

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HPLC column "IEC・HIC・Affinity"

HPLC column "IEC・HIC・Affinity"

This is a book that explains the features and physical properties of ion exchange chromatography and other related topics.

This document explains the IEC, HIC, and affinity of HPLC columns. It introduces the characteristics of ion exchange chromatography columns, as well as basic physical properties. Additionally, it explains each product series using tables. Furthermore, it also includes information on hydrophobic chromatography and affinity chromatography. 【Contents (excerpt)】 ■ Ion Exchange Chromatography ■ Hydrophobic Chromatography ■ Affinity Chromatography *For more details, please refer to the PDF document or feel free to contact us.

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"Cogent TYPE-C Silica" HPLC column

"Cogent TYPE-C Silica" HPLC column

Unique "TYPE-C Silica" used in columns for Cogent HPLC manufactured by MicroSolv in the USA.

The "Cogent TYPE-C column," developed by MicroSolv in the United States, is a next-generation HPLC column based on high-purity Type-B silica that has been modified to replace over 95% of the silanol (Si-OH) on the silica surface with silane (Si-H). By replacing over 95% of the silanol with Si-H, a strong hydrophobic surface is created, providing greater stability compared to traditional silica-based phases. This means that end-capping is not necessary. 【Features】 ■ Usable in three modes in HPLC (RP (reverse phase), NP (normal phase), ANP (aqueous normal phase)) ■ High efficiency and high stability ■ Fast equilibration in gradient ■ Simultaneous separation of polar and non-polar compounds ■ Weak hydration shell *For more details, please refer to the catalog.

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ACE UltraCore UHPLC·HPLC Column

ACE UltraCore UHPLC·HPLC Column

Solid core (core-shell) particles appear in the ACE column! Unique EBT technology achieves high stability across a wide pH range.

A new UltraCore column (HPLC/UHPLC column) has been added, featuring solid core (surface porous) particles from the UK ACE column group. Compared to conventional fully porous silica, it can be used at lower pressures, and due to the limited diffusion of analytes, it achieves high efficiency and sharp peak shapes. Additionally, it employs a unique encapsulation bonding technology (EBT) that delivers stable high performance across a wide pH range, dramatically increasing the ligand coverage on the silica surface and effectively eliminating the negative effects of unbound silanols. **Features** - Utilizes ultra-inert solid core particles (surface porous) - Monodisperse particle distribution combining low pressure and high efficiency - Expanded pH stability (1.5 to 11.0) - Compatible with LC/MS buffers - Employs unique encapsulation bonding technology (EBT)

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Various columns for gas chromatography (GC) made by MEGA Corporation (Italy)

Various columns for gas chromatography (GC) made by MEGA Corporation (Italy)

We will provide valuable products at prices that satisfy our customers. Please feel free to consult us regarding your requests for the inner diameter, length, film thickness, etc., of the columns, as well as for demo columns.

MEGA Corporation has been manufacturing and selling GC columns developed in collaboration with Dr. Kurt Grob, a global authority on Fused Silica GC Capillary Columns, since 1980. Based on this technological expertise, we have acquired the "manufacturing and sales rights for Grace Corporation GC columns" and are further expanding our product range. While it is natural that our performance and lineup meet the diverse needs of our customers, another notable feature is our "pricing." ■ Unique Services Offered by MEGA 1. We actively respond to inquiries about "MEGA Customized Columns" that meet customer requests for inner diameter, length, film thickness, etc. 2. To ensure that you can start measuring immediately after purchase, we also perform "aging" as a pre-treatment before shipping, so please specify "aging" at the time of purchase. 3. We accept requests for "demo columns" for evaluation purposes. *For more details, please contact us or download the PDF materials.

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ACE C18-AR HPLC Column

ACE C18-AR HPLC Column

Mixed-mode HPLC column integrating C18 and phenyl groups.

This is an HPLC column manufactured by ACT in the UK, featuring a unique selectivity that integrates a phenyl group into a conventional C18 stationary phase. While it is a C18 phase, it exhibits selectivity for aromatic compounds like phenyl groups, providing complementary selectivity when sufficient separation cannot be achieved with C18 alone. **Features:** - A C18-phenyl integrated column that combines the advantages of both C18 phase and phenyl groups. - Utilizes ultra-high purity inert silica, demonstrating excellent peak shape and reproducibility. - Can be used with a water-rich mobile phase that enables retention and separation of polar substances. - Exhibits ultra-low bleed characteristics required for UV/LC-MS. - High-throughput column size.

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ACE C18-PFP HPLC column

ACE C18-PFP HPLC column

HPLC column with pentafluorophenyl (PFP) group bonded to C18 phase.

This is an HPLC column developed by ACT in the UK, combining C18 with a PFP group. By integrating the PFP phase, which provides complementary selectivity to conventional C18, it improves the separation of polar basic substances and demonstrates selective characteristics for halogenated aromatic compounds and positional isomers. Additionally, the C18-PFP phase possesses multiple separation mechanisms (hydrophobic, π-π, hydrogen bonding, shape selectivity), showcasing its capabilities for mixtures that are difficult or impossible to separate with conventional C18. **Features** - A mixed column that combines C18 and PFP (PentaFluoroPhenyl) phases - Enhanced separation capability for polar basic substances - "Ultra-inert & Ultra-pure silica" essential for peak shape and reproducibility - Excellent stability for temperature programming analysis - Optimal for UV and LC/MS due to ultra-low bleed characteristics

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Roc C8 HPLC column (USP L7)

Roc C8 HPLC column (USP L7)

Solid high reliability – provides the peak shape, reproducibility, robustness, and separation performance desired by users.

The Roc C8 HPLC column (USP L7) is designed to become a "standard" in LC analysis laboratories. These robust and highly reliable columns are compatible with HPLC systems that can withstand pressures up to 40 MPa, providing users with the desired peak shape, reproducibility, robustness, and separation performance for all LC applications. Their exceptional utility maximizes operational efficiency. The minimal package design allows for compact storage. 【Features】 ■ Designed to be a "standard" in LC analysis laboratories, this standard HPLC column is compatible with HPLC systems that can withstand pressures up to 40 MPa. ■ Solid high reliability – provides users with the desired peak shape, reproducibility, robustness, and separation performance. ■ Exceptional utility capable of handling a large volume of analytical tasks – diverse packing materials using high-purity silica backed by high-quality manufacturing processes are suitable for most HPLC methods. *This catalog is in English. *For more details, please download the PDF or contact us.

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Inert LC Columns

Inert LC Columns

Improve peak shape without using additives! Achieve high precision and throughput.

We would like to introduce our "Inert LC Column." We offer two products: Raptor Inert Biphenyl HPLC Columns and Raptor Inert ARC-18 HPLC Columns. There is no need for time-consuming conditioning or complex passivation. Additionally, the response and recovery rates of analytes are improved, lowering the detection limits. 【Four Benefits】 ■ Improved peak shape without using passivation or additives in the mobile phase ■ Enhanced response and recovery rates of analytes, resulting in lower detection limits ■ Minimization of variability in analytical results, achieving high precision and throughput ■ Elimination of the need for time-consuming conditioning and complex passivation *For more details, please refer to the PDF document or feel free to contact us.

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