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This is a fiber optic cannula suitable for fiber photometry. The main models are in stock.
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Free membership registrationMeasurement Method: Interleaved Method (when using 2 or 3 wavelengths) Multiple wavelength LED light sources are pulsed in sequence, and the fluorescent signals corresponding to those emission wavelengths are captured by a CMOS camera. Number of Measurement Channels: Up to 9 ROIs can be measured simultaneously (when using a 200μm core diameter optical fiber). This allows for the observation of multiple animals at the same time, or the simultaneous observation of multiple locations on a single animal.
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Free membership registrationSingle-core optical fiber patch cords are the simplest type of patch cord (patch cable) with a single optical fiber. - Standard model: Connectors are attached to both ends of the regular optical fiber. - LAF model: A model that uses LAF (low auto-fluorescence optical fiber), ideal for fiber photometry. - Model with attenuation function: This model has the ability to attenuate the transmitted optical power. It is used when adjusting weak power in fiber photometry. - You can choose from over 10 types of connectors. Each connector can be specified in a different type.
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Free membership registrationThe Doric company's optical fiber rotary joint is a device that prevents tangling and twisting of patch cords connected to biological systems in applications such as fiber photometry and optogenetics. The input side (fixed side) is connected to a light source via a patch cord, while the output side (rotating side) connects to a patch cord attached to the biological system. We offer a wide variety of models, including the most common 1x1 type for transmitting optical power, as well as types that split optical power, types that split wavelengths, and types that transmit electrical signals.
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Free membership registrationThe fiber optic rotary joint manufactured by Doric is a device that prevents tangling and twisting of patch cords connected to biological systems in applications such as fiber photometry and optogenetics. The input side (fixed side) is connected to a light source via a patch cord, while the output side (rotating side) connects to a patch cord linked to the biological system. We offer a wide variety of models, including the most common 1x1 type for transmitting optical power, as well as types that split optical power, types that split wavelengths, and types that transmit electrical signals.
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Free membership registrationThe dual optical fiber cannula is a type that accommodates two optical fibers in a single receptacle. It is used for applications that require stimulation/inhibition at two symmetrical or simultaneous locations. The spacing and insertion depth of the two optical fibers are specified and confirmed during manufacturing, which helps resolve issues such as limitations in spacing distance and increased positional errors that can occur when using two single-core optical fiber cannulas. We offer two types: one with a guide socket for secure connection and another with guide pins. Corresponding patch cords (DFP: Dual Fiber-optic Patch Cords) are also available for use with them.
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Free membership registrationOne method for observing neuronal activity under free behavior is the head-mounted fluorescence microscope. The microscope body weighs only 3 grams and is equipped with a CMOS sensor, an electronic focusing mechanism (focal depth 0-300μm), and filters. An imaging cannula (GRIN lens) is inserted into the animal's head, capturing images at the lens tip with the CMOS sensor. This model adds a light stimulation function (optogenetics): NpHR halorhodopsin activation capability to the aforementioned features. The microscope body and the imaging cannula (GRIN lens) are securely and easily fixed with screws, and no special fixtures are required for fixation. Four types of imaging cannulas are available, depending on the depth of the target to be observed and the diameter of the GRIN lens. By using an imaging cannula equipped with a prism at the tip, it is also possible to observe sagittal or coronal sections.
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Free membership registrationOne method to observe neuronal activity under free movement is the head-mounted fluorescence microscope. The main body of the fluorescence microscope weighs only 3 grams and is equipped with a CMOS sensor, an electronic focus mechanism (with a depth of focus of 0-300μm), and filters. An imaging cannula (GRIN lens) is inserted into the animal's head, capturing images at the lens tip with the CMOS sensor. The microscope body and the imaging cannula (GRIN lens) are securely and easily fixed with screws, and no special fixtures are required for fixation. Four types of imaging cannulas are available, depending on the depth of the target to be observed and the diameter of the GRIN lens. By using an imaging cannula equipped with a prism at the tip, it is also possible to observe sagittal or coronal sections.
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Free membership registrationThe OASIS Implant is a fluorescence imaging fiber scope that responds to light stimulation in any area under free movement. Unlike typical head-mounted micro-fluorescence microscopes, it houses optical devices such as cameras and filters for calcium imaging on a platform body separate from the animal. This reduces the weight burden on the animal's head and allows for the use of higher resolution cameras. All equipment that can be attached to the platform body, including cameras, light sources, and filters, is interchangeable, enabling observations using different fluorescent proteins with a single device.
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Free membership registrationThe optical fiber output visible light semiconductor laser source is used as a light source for optogenetics and fluorescent lighting. There are different types of lasers, and the semiconductor laser is called LD: Laser Diode. The semiconductor laser source manufactured by Doric has the laser oscillation resonator inside the semiconductor chip, allowing visible light to be emitted directly from the resonator. Therefore, it can achieve very stable output even with high-frequency pulse oscillation. Additionally, there is no concern about output reduction due to alignment shifts. Since the laser light source has a very narrow linewidth, the optical fibers used typically have an NA of 0.22 and a core diameter of 200 μm. Optical fiber core diameters starting from 50 μm can also be used.
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Free membership registrationThe optical fiber output LED light source is the easiest light source to introduce for optogenetics and fluorescent lighting. Due to its wide wavelength range (bandwidth) and uniform irradiation intensity, it is excellent not only for optogenetics (light stimulation) but also as a light source for fiber photometry and head-mounted fluorescence microscopy, and is widely used. The LED light sources from Doric, a lens manufacturer, boast high fiber coupling efficiency and feature a diverse lineup, including combined types that integrate multiple wavelengths and types that are integrated with rotary joints. The output of the LED light source varies depending on the core diameter and NA of the connected optical fiber patch cord.
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Free membership registrationSpotlight LED Light Source: The PLS series is an LED light source with a uniform power distribution in the irradiation area. By combining high-output LED chips with aspheric lenses, it achieves a uniform power distribution across the entire irradiation area. The standard range model can be used at a working distance of 100mm or more. As the working distance increases, the beam diameter also increases, but a uniform power distribution can be obtained. The close range model can be used at a working distance between 75mm and 100mm. Please note that if you go outside this working distance, a uniform power distribution cannot be achieved.
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Free membership registrationFiber Optic Output LED Light Source: The FCS series is an LED light source with SMA connector output. The final output varies depending on the core diameter and NA of the connected fiber optic patch cord. The larger the core diameter and NA, the greater the power obtained. When selecting a fiber optic patch cord, it is necessary to consider factors such as the desired beam spot diameter. Wavelength options include UV, visible light, infrared, and white light.
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Free membership registrationMulti-wavelength LED light source for optical fiber output: The WFC series is an LED light source that outputs 2, 4, 6, or 8 wavelengths from a single housing via SMA connectors. Power and output waveforms can be controlled for each wavelength. You can specify the combination of wavelengths, but some combinations may not be supported, so please inquire. Wavelengths can be selected from UV, visible light, infrared, and white light.
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Free membership registrationMulti-wavelength Rotating Selective LED Light Source: WLS Series, WheeLED is an LED light source that can accommodate up to nine wavelengths in a single housing, allowing you to select the wavelength by manually rotating a dial. While high-speed switching is not required, it is suitable for applications that require multiple wavelengths. It can be used as a collimated light source or as a light guide output source using a light guide adapter. Please select the wavelengths from the list below. You can also specify the order in which they are mounted. Please switch wavelengths after turning off the power.
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Free membership registrationLight guide output LED light source: The GCS series is an LED light source that efficiently connects to light guides. The high-output model Type-H can achieve approximately 2W of high output at a wavelength of 470nm. A variety of wavelengths are available, ranging from the UV region to the visible light region commonly used in biosciences, as well as the infrared region and white light. The standard is for light guides with a ferrule diameter of 5mm and a core diameter of 3mm, but it can also accommodate light guides of other sizes.
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Free membership registrationCollimated LED Light Source: The LCS series is the most versatile LED light source. It can be used in a single color, as well as in combinations of multiple wavelengths. It can also be used as a light source for microscopes by using light guide adapters or microscope adapters.
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Free membership registrationThis is an optogenetics starter kit. It is available in configurations with a laser light source and an LED light source. This optogenetics starter kit is produced by Doric Lenses, a pioneer in the field of optogenetics based in Canada. Optogenetics Starter Kit Laser Light Source Excitation Set This is the simplest configuration for optical stimulation using a laser light source. Wavelengths of 405nm, 450nm, 473nm, 488nm, 520nm, and 638nm are available. The starter kit can also be configured with wavelengths other than 450nm, 473nm, and 488nm. Optogenetics Starter Kit LED Light Source Excitation Set This is the simplest configuration for optical stimulation using an LED light source. It is ideal when high output like that of a laser is not required. The starter kit can also be configured with wavelengths other than 465nm and 560nm.
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Free membership registrationIn neuroscience, fiber photometry is a method that involves an embedded optical fiber that illuminates neurons tagged with a fluorescent calcium indicator with excitation light and detects the fluorescence emitted from their activity for observation and measurement. In fiber photometry, the fluorescence activity of all neurons within the detection range of the optical fiber cannula is captured as a single signal, even if there are multiple active locations.
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Free membership registrationA fiber optic connector conversion adapter is a component used to connect patch cords or optical components of different connector types. A fiber optic connector coupling adapter is a component used to connect male connectors of the same shape. A bare fiber adapter is a component used when you want to connect bare fiber to a connector.
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Free membership registrationThe fiber optic output Ce:YAG light source is a broadband light source that outputs wavelengths in the green, yellow, orange, and red regions. It emits wavelengths that are difficult to achieve with LED or laser light sources. Like LED and laser light sources, it can also be modulated. Equipped with a filter holder, it allows for the insertion of any bandpass filter to extract any desired wavelength. A model that combines a blue LED light source (465nm) or a blue laser light source (450nm or 473nm) in a single housing is also available.
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Free membership registrationOptiphase's high-speed fiber stretcher features a structure that multilayer wraps optical fibers around a piezo element, achieving fast modulation (optical delay). It is very compact and easy to install. Its main applications include measurements and sensing using optical interference, as well as generating optical delays. We offer models that use not only single-mode fibers but also polarization-maintaining fibers and RC fibers. It supports a wide range of fiber types from the visible spectrum to the infrared range.
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Free membership registrationThis is a Deep UV LED light source. It is a collimated light output type. We offer 10 wavelengths in the range of 240nm to 340nm. It can be used with a dedicated LED controller from Mightex. It features heat sink cooling. The collimator lens is adjustable, allowing for optimal collimation settings. It can also be connected to a liquid light guide. It is possible to combine two wavelengths using a combiner. It can also be connected to microscopes (compatible with Nikon, Olympus, Leica, Zeiss).
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Free membership registrationThe optical fiber cannula, essential for InVivo optogenetics, is a component made of a zirconia ceramic or metal ferrule and optical fiber. The tip of the optical fiber is the side that will be implanted. There are diameters of 1.25mm and 2.5mm available. The most commonly used type for insertion into mouse brains has a ferrule made of zirconia ceramic with a diameter of 1.25mm (ZF1.25), and the optical fiber part is of type 200/240-0.22. The length of the optical fiber part can be specified in 0.1mm increments depending on your application (tolerance is <0.1mm). Additionally, multiple shapes of the optical fiber tip are available depending on the type of light diffusion. This optical fiber cannula connects to a patch cord via a sleeve, allowing light from the light source connected to the patch cord to be irradiated onto the brain or biological tissues. The zirconia ceramic version is recommended as it is lighter and places less burden on the organism compared to the metal version.
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Free membership registrationA DMD (Digital Mirror Device) method arbitrary area light stimulation module that realizes light stimulation in the exact shape (pattern), wavelength, and intensity as envisioned for the targeted area. It can be easily used in combination with your existing microscope. When combined with OASISImplant, it enables the construction of a groundbreaking system for arbitrary area light control under free behavior conditions. The included dedicated software allows you to control the pattern of light irradiation, the intensity of the light source, and the timing of irradiation, focusing only on the necessary areas of the sample. It is designed for easy attachment to both inverted and upright microscopes using adapters and other accessories.
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