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Ion chromatography, ion chromatograph, bauxite ore, ore, alumina. This is an application that quantifies fluoride, acetate, formate, chloride, sulfate, malonic acid, succinic acid, and oxalic acid contained in the Bayer liquor produced by the process of obtaining pure alumina from bauxite ore (Bayer process).

This is an application that quantifies fluoride, chloride, phosphates, monofluorophosphate, and sulfates in toothpaste using anion exchange chromatography.

This is a pharmaceutical-related application for ion chromatography. It can be downloaded.

Adsorptive Organic Fluorine (AOF) is the sum value that covers a wide spectrum of organic fluorine. AOF analysis is an appropriate screening analytical method for PFAS in water. DIN 38409-59 conducts AOF analysis using combustion ion chromatography (CIC), which combines a pyrolysis device and an ion chromatograph – AOF analysis can be performed using Metrohm's combustion ion chromatography system.

Most organic fluorine compounds are assumed to be the total of all adsorbable organic fluorine (AOF) compounds in water. The measurement of AOF is simpler and faster than target analytical methods, and it is more sensitive than total fluorine (TF) measurements (which include all organic and inorganic F). Measuring AOF in water samples as an initial screening process allows for the screening of the actual amounts of organic fluorine compounds present. Following this, if indicated by high AOF concentrations, it can serve as a criterion for conducting target analysis of individual PFAS.

Manual preparation of elution solutions is time-consuming and poses safety risks, especially when handling corrosive substances, increasing the likelihood of human error. Automation effectively addresses these challenges. Automated generation of elution solutions ensures stable retention times, contamination-free safe operations, and reliable measurement results. Reagent preparation for analysis is almost unnecessary 24/7, allowing for a focus on analysis and saving time and costs.

We conducted the analysis by connecting the Metrohm ion chromatography (IC) to an Agilent triple quadrupole mass spectrometer (MS). This high-sensitivity method does not require sample extraction and can eliminate interferences from the eluent due to the Metrohm suppressor module. The matrix spike recovery rate for all target analytes at 1 μg/L was between 65% and 115%, and good results were obtained even with highly contaminated water samples.

The US EPA Method 300.1 (Parts A and B), ISO 10304-1, and ISO 10304-4 are conducted to ensure compliance when monitoring water quality contaminants that affect human health. In particular, disinfection by-products (DBPs) are associated with carcinogenicity and reproductive effects. EPA Method 300.1 Part A and ISO 10304-1 specify the requirements for quantitative analysis of major inorganic anions by ion chromatography.

Even in customized online industrial processes with multiple parameters and streams, monitoring using ion chromatography becomes possible. The 2060 IC Process Analyzer, based on the 2060 online analysis platform, is a highly flexible and perfect system suitable for online monitoring of ionic compounds in aqueous media at concentrations ranging from ng/L to the % order.

2060 MARGA is a fully autonomous sampling and measurement system that can continuously measure water-soluble gases and aerosol components that directly affect air quality. The measurement results can be used in research to identify the structure of aerosols and to investigate how their concentration and composition change with diurnal and seasonal cycles.

The presence of carcinogenic nitrosamines in pharmaceuticals poses a threat to patient safety. By controlling the concentration of nitrites in drugs and processes, the formation of nitrosamines can be prevented, making it essential to have a highly sensitive method for analyzing nitrites in pharmaceuticals and their raw materials. In many cases, dimethylamine is used in the synthesis of various drugs. Under acidic conditions, it reacts with nitrites to form nitrosamines. This also applies to the production of hydroxypropyl methylcellulose (HPMC), a common excipient. This technical document introduces the quantification of nitrites in hydroxypropyl methylcellulose using ion chromatography (IC) with direct UV/VIS detection.

Duloxetine hydrochloride is an active pharmaceutical ingredient (API) for the treatment of depression and other neurological disorders. This technical document presents the analysis of nitrite in duloxetine hydrochloride using ion chromatography (IC) with a Metrosep A Supp 10 column equipped with direct UV/VIS detection at 215 nm.

Measurement of alendronate using anion exchange chromatography.