メイプルバイオラボラトリーズ List of Products and Services

We offer a "paw cream" made with natural plant-derived jojoba oil, argan oil, and shea butter. Since it is formulated with only natural ingredients, it is safe for dogs to lick. No preservatives or surfactants are used. Additionally, the jojoba oil used in the ingredients is easily absorbed and has high moisturizing effects, preventing skin dryness and regulating sebum secretion, which promotes the normalization of turnover. 【Product Concept】 - Made with natural plant-derived jojoba oil, argan oil, and shea butter - Contains natural essential oils - Safe for dogs to lick (formulated with only natural ingredients) - No preservatives or surfactants used - Fragrance-free - Smooth and moist texture *For more details, please download the PDF or feel free to contact us.

• Cosmetic materials and raw materials

"Love Dog Prefere" is a pet food designed to enhance the appetite of dogs that are picky eaters, sick, or elderly. By adding a small amount (about 5 to 10 pieces) to their regular food, it is possible to restore your pet's appetite. Additionally, since no heat is applied to the ingredients, all the nutrients from the materials are preserved. No other substances are used. [Ingredients] - Chicken breast - Carrot - Pumpkin - Sweet potato - Turnip (leaves) - Whitebait - Hijiki seaweed *For more details, please download the PDF or feel free to contact us.

• Other food and beverage ingredients

Alcohol, alcohol. Speaking of alcohol, it refers to alcoholic beverages. Alcohol is said to be the best medicine, which serves as a justification for those who enjoy drinking. On the other hand, excessive drinking is not good for the liver, and considering the effects alcohol may have on the brain, underage drinking is prohibited by law, and it is a red flag for pregnant women. Alcohol plays a significant role in settings where hygiene is crucial, such as hospitals. When getting an injection, nurses disinfect the skin with cotton soaked in alcohol. It is also a handy item for cleaning the refrigerator and organizing shelves. *For detailed content of the article, please refer to the PDF. For more information, feel free to contact us.*

• Cosmetic materials and raw materials

The role of toner. In the case of Lushene cosmetics, if I were to sum up the role of toner in one word, it would be "hydration." Have you ever thought that if it's just "hydration," plain water would suffice? But in reality, plain water cannot provide adequate hydration to the skin. This is related to the chemical concept of "osmotic pressure." *You can view the detailed content of the article in the PDF. For more information, please feel free to contact us.*

• Cosmetic materials and raw materials

Did you know that there are cosmetics containing ATP in the products of Ruchene Cosmetics? ATP is included in two products: toner and emulsion. So, I would like to discuss why we included this unfamiliar ingredient "ATP" and what ATP actually is. ATP stands for adenosine triphosphate, and it is abbreviated as "ATP." *For detailed content of the article, you can view it in the PDF. Please feel free to contact us for more information.

• Cosmetic materials and raw materials

Did you know that the "solid soap" you casually use is actually made through a chemical reaction? When represented generally in chemical formula, solid soap is… R-COONa. The raw materials are fats and sodium hydroxide (also known as "caustic soda"). Soap is created through the chemical reaction that occurs when these two are mixed together. *You can view the detailed content of the article in the PDF. For more information, please feel free to contact us.

• Cosmetic materials and raw materials

pH (pee-aitch / pee-ha). This is a term that anyone has probably heard at least once. You may remember measuring whether familiar substances are acidic or alkaline using "litmus paper" during science class in elementary school. Now, do you know what pH stands for? *For detailed content of the article, you can view it in the PDF. Please feel free to contact us for more information.*

• Cosmetic materials and raw materials

It is said that there are one million types of microorganisms on Earth. However, only about 20,000 to 30,000 of these have been identified so far. The microorganisms discovered by humanity so far represent only a tiny fraction of the whole, making them mysterious beings. Have you ever considered that these microorganisms are indispensable to us humans? When we think of "bacteria," many may associate it with negative images such as "disinfection," "antibacterial," "decontamination," and "sterilization." However, there are certainly beneficial bacteria, such as "yeast," "natto bacteria," and "lactic acid bacteria," that play a role in our daily lives. So why are bacteria essential? This is because the functions of bacteria significantly benefit us humans, and they maintain a balance among themselves, coexisting with us. *You can view the detailed content of the article in the PDF. For more information, please feel free to contact us.*

• Cosmetic materials and raw materials

After washing your face, it's often said to apply lotion and then immediately put on emulsion to "seal in moisture for your skin." Have you ever thought that if a seal is necessary, it might not have to be emulsion specifically? At Ruchene Cosmetics, we consider the seal to be synonymous with emulsion and recommend it. So, why emulsion instead of oil, and what role does emulsion play? I would like to discuss this today. *For detailed content of the article, you can view it in the PDF. Please feel free to contact us for more information.*

• Cosmetic materials and raw materials

The skin has a three-layer structure consisting of the "epidermis," "dermis," and "subcutaneous tissue," starting from the surface. The outermost layer is the "epidermis," where new cells are constantly being produced. After the cells in the basal layer divide, they move upward while growing, gradually digesting their contents until they reach the surface, where the remaining lipid membrane becomes dead skin cells that flake off. A healthy epidermis regenerates approximately every 28 days. This regeneration is called turnover. *For detailed content of the article, you can view it in the PDF. Please feel free to contact us for more information.*

• Cosmetic materials and raw materials

Our company conducts contract research and development, as well as quality control and testing (microbial testing, stability testing, etc.) for pharmaceuticals, quasi-drugs, medical devices, cosmetics, and food products. The metabolism of products, along with product development and research and development, is essential for corporate growth. However, significant upfront investments in manpower, development equipment, and facilities are required, making in-house development challenging. To avoid the risks associated with in-house development, we outsource research and development to external research institutions. 【Features】 ■ No need to employ full-time researchers ■ No need to purchase specialized development and measurement equipment ■ No need to secure facilities for research and development ■ Development costs are significantly reduced compared to in-house development ■ Fresh proposals incorporating know-how from different industries are possible *For more details, please download the PDF or feel free to contact us.

• Cosmetic materials and raw materials
• Product Development
• Microbiology

We would like to introduce "Lushene Cosmetics," handled by Maple Bio Laboratories. We offer "Lushene Foaming Soap," which allows for easy massage with its fine bubbles, and "ATP-Infused Lotion," which contains ATP (Adenosine Triphosphate 2Na) to provide moisture and firmness to the skin, along with other products such as emulsions, moisturizing creams, and cleansers. You can choose according to your needs and preferences. Please feel free to consult us when you need assistance. 【Product Lineup (Partial)】 ■ Lushene Foaming Soap ■ Lushene Soap ■ ATP-Infused Soap ■ Soap (Normal) ■ Soap (Clay) *For more details, please download the PDF or feel free to contact us.

• Cosmetic materials and raw materials

Lushene Cosmetics Co., Ltd. was established in 2013 as a company selling basic skincare products. Maple Bio Laboratories, which develops and manufactures cosmetics, began working on the development of cosmetics that can be offered to consumers without the use of preservatives, resulting in "Lushene Cosmetics." "Lushene Cosmetics" does not contain synthetic surfactants, mineral oils, synthetic fragrances, or other ingredients that are unsuitable for the purpose of keeping skin and hair healthy. 【Features of Lushene Cosmetics】 ■ Softens the stratum corneum and retains moisture ■ Balances moisture and oil ■ Provides a refreshing cleanse ■ Tightens muscles and adds firmness *For more details, please download the PDF or feel free to contact us.

• Cosmetic materials and raw materials

(Our company has obtained licenses for cosmetics manufacturing and cosmetics manufacturing and sales, and tests will be conducted by clinical laboratory technicians in testing facilities (BSL2) in accordance with the Pharmaceutical and Medical Device Act.) We will determine the level of microbial contamination from the detected colonies and report it in a list. In standard tests, we conduct examinations as a set for total viable count (an indicator of microbial contamination), coliform bacteria (an indicator of environmental contamination from dust, etc.), Escherichia coli (fecal contamination), and Staphylococcus aureus (caused by injuries to the hands of workers). If desired, it is also possible to add Pseudomonas aeruginosa, Salmonella, Vibrio parahaemolyticus, Campylobacter, Bacillus cereus, O157, MRSA, periodontal bacteria, Legionella, Serratia, etc.

• Hygiene Management

In standard testing, total viable count, coliforms, E. coli, and Staphylococcus aureus are tested as a set. Upon request, it is also possible to add Pseudomonas aeruginosa, Salmonella, Vibrio parahaemolyticus, Campylobacter, Bacillus cereus, O157, MRSA, periodontal pathogens, Legionella, Serratia, etc. Measurement of antibacterial activity using the above microorganisms (inhibition zone, mixed culture) is also possible. The method for calculating the coal tar coefficient involves varying the concentration of the antibacterial substance in several ways and varying the reaction time with the microorganisms at several points, performing a mixed culture that combines concentration and reaction time. This allows us to determine the relationship between the concentration of the antibacterial substance and the reaction time, enabling the assessment of the immediate and sustained efficacy of the antibacterial agent. Preservative efficacy testing (compliant with JP, USP, EP) involves dropping five types of microorganisms into pharmaceuticals, etc., and measuring the microbial count after a certain storage period. This method investigates the effectiveness of microbial control when microbial contamination occurs in the relevant pharmaceuticals, etc. Aseptic testing determines whether there is no microbial contamination in cosmetics, pharmaceuticals, etc.

• Safety Management

We visit restaurants, food stores, food factories, supermarket backyards, coffee shops, hotel kitchens, golf course kitchens, funeral home kitchens, etc., on a regular monthly basis to conduct wipe tests using swabs on the equipment within the manufacturing facilities. We assess the level of microbial contamination based on the colonies detected and report the findings in a summary table. In standard testing, we conduct tests as a set for total viable count (an indicator of microbial contamination), coliform bacteria (an indicator of environmental contamination from dust, etc.), E. coli (fecal contamination), and Staphylococcus aureus (caused by cuts on the hands of food handlers). If desired, we can also add tests for Salmonella (bacterial contamination of meat), Vibrio parahaemolyticus (bacterial contamination of fish), Campylobacter (bacterial contamination of poultry), etc. Typically, we perform wipe tests at five locations and take one sample of food for testing, while simultaneously checking and noting the hygiene conditions through visual inspection. The results are compiled into a scoring sheet, allowing for easy observation of fluctuations throughout the year. (Compliance with the Food Sanitation Act and HACCP)

• Hygiene Management

Expiration Date Setting Test The expiration date indicates the period during which food can be safely consumed, typically focusing on perishable ingredients and showing a short duration of a few days to a few weeks. It is often determined based on the proliferation of microorganisms. Best Before Date Setting Test The best before date indicates the period during which food can be enjoyed at its best quality, usually focusing on shelf-stable ingredients and showing a longer duration of a few weeks to several years. It is often determined based on indicators such as water activity, oil acidity, and the denaturation of components like proteins. Accelerated Testing; When setting the best before date, conducting tests over a long period can often be impractical, so a method is employed to shorten the storage period by raising the storage temperature and using theoretical calculations (Arrhenius equation = when the temperature increases by 10°C, the reaction time doubles) to conduct accelerated testing.

• Safety Management

We will send food ingredients and products from restaurants, food stores, food factories, supermarket backyards, coffee shops, hotel kitchens, golf course kitchens, funeral home kitchens, etc., and conduct microbiological testing. We will examine the level of microbial contamination in food and ingredients based on the colonies detected. We will provide indicators of the hygiene status of the ingredients being manufactured. In standard testing, we conduct tests as a set for total viable count (an indicator of bacterial contamination), coliform bacteria (an indicator of environmental contamination from dust, etc.), E. coli (fecal contamination), and Staphylococcus aureus (caused by cuts on the hands of food handlers). If desired, we can also add tests for Salmonella (bacterial contamination of meat), Vibrio parahaemolyticus (bacterial contamination of fish), Campylobacter (bacterial contamination of chicken), lactic acid bacteria, fungi (molds, yeasts), etc. We will conduct tests to establish the expiration date and best-before date of food products. In the case of measuring the best-before date, if the storage period is long, it is also possible to conduct accelerated tests. (In compliance with the Food Sanitation Act)

• Other contract services

Research on Pharmaceuticals, Quasi-druga,　Medical devices, Cosmetics,　and Foods Quality control and Inspection (Microbial test, Preservative effect, etc) Microbial Testing Department = We conduct product testing, manufacturing equipment inspections, environmental swab tests, and visual hygiene inspections and quality control at restaurants, food factory kitchens, cosmetics company manufacturing facilities.

• Other purification and extraction

At Maple Bio Laboratories, we conduct contract research and development for pharmaceuticals, cosmetics, and food products. Here, we would like to introduce one example of a cosmetic developed under the concept of "no unnecessary ingredients." 【Cosmetic OEM Example 5】 Lushene ATP Emulsion EX 120mL with a light lavender scent 【Features】 - The formula consists of only 10 ingredients: water, glycerin, soap base, almond oil, squalane, argania spinosa kernel oil, carrageenan, tocopherol, ATP, and essential oils. - No preservatives or synthetic surfactants used. - The emulsification of oil in water is achieved using soap base instead of synthetic surfactants. - Moisturizing effect from argan oil (argania spinosa kernel oil). - Packaged in an airless container to prevent exposure to air. We are currently sending out samples through a lottery. *For more details, please refer to the PDF or feel free to contact us.

• Other Testing Contract
• Other contract services

At Maple Bio Laboratories, we conduct contract research and development for pharmaceuticals, cosmetics, and food products. Here, we would like to introduce one example of a cosmetic developed under the concept of "not using unnecessary ingredients." 【Cosmetic OEM Example 4】 Lushene Emulsion EX 120mL with a light lavender scent 【Features】 - Contains only seven ingredients: water, squalane, soap base, glycerin, tocopherol, carrageenan, and essential oil. - No preservatives or synthetic surfactants used. - The emulsification (dissolving oil in water) is achieved using soap base instead of synthetic surfactants. - Moisturizing effect from argan oil. *Packaged in an airless container to prevent exposure to air. *For more details, please refer to the PDF or feel free to contact us.

• Other Testing Contract
• Other contract services

At Maple Bio Laboratories, we conduct contract research and development for pharmaceuticals, cosmetics, and food products. Here, we would like to introduce one example of a cosmetic developed under the concept of "no unnecessary ingredients." 【Cosmetic OEM Example 3】 Lushene ATP Lotion 120mL Fragrance-Free 【Features】 - All ingredients include water, glycerin, urea, ethanol, ascorbic acid, citric acid, and ATP, totaling seven. - No preservatives or synthetic surfactants used. - Gentle on the skin, suitable for those with sensitive skin. - Packaged in an airless container to prevent exposure to air. (#ATP is the energy source produced in cells for movement. It provides firmness and moisture to the skin.) *For more details, please refer to the PDF or feel free to contact us.

• Other Testing Contract
• Other contract services

At Maple Bio Laboratories, we conduct contract research and development for pharmaceuticals, cosmetics, and food products. Here, we would like to introduce one example of a cosmetic developed under the concept of "not using unnecessary ingredients." 【Cosmetic OEM Example 2】 Ruchene Solid Soap 80g 【Features】 - Cleanses skin impurities while maintaining moisture - A simple handmade soap made only with soap base combining sweet almond oil and coconut oil, along with essential oils - Free from preservatives, synthetic surfactants, foaming agents, and chelating agents - Scented with natural aroma *For more details, please refer to the PDF or feel free to contact us.

• Other Testing Contract
• Other contract services

At Maple Bio Laboratories Co., Ltd., we conduct contract research and development for pharmaceuticals, cosmetics, and food products. Here, we would like to introduce one example of a cosmetic developed under the concept of "not using unnecessary ingredients." 【Cosmetic OEM Example 1】 Lushene Cosmetic Soap (Foam Type) 200 milliliters 【Features】 - Cleanses skin impurities while retaining moisture - Contains argan oil with high beauty benefits - Maintains a low pH to reduce burden on the skin - Free from preservatives and synthetic surfactants - Usable by the whole family - Subtle fragrance of natural aroma *For more details, please refer to the PDF or feel free to contact us.

• Other Testing Contract
• Other contract services

The streets are filled with the word "collagen." It is often seen in cosmetic formulations as well. So, what exactly is collagen? Let me explain it in an easy-to-understand way. Maple Bio Laboratories Co., Ltd. manufactures and sells cosmetics developed under the concept of "not using unnecessary ingredients." *For more details, please refer to the PDF or feel free to contact us.

• Other Testing Contract
• Other contract services

"Cosmetic development and contract manufacturing" utilizes expertise in microbiological testing to develop and manufacture cosmetics that do not use preservatives or synthetic surfactants. 【Features】 ■ We offer contract manufacturing of cosmetics starting from small-scale production. ■ We conduct formulation tests for cosmetics. ■ We perform verification of manufacturing methods. ■ We conduct acceptance testing for cosmetic raw materials and outgoing testing for products. *For more details, please refer to the PDF or feel free to contact us.

• Other Testing Contract
• Other contract services

"Microbial Testing and Sanitation Testing" are conducted by our company for facilities such as restaurants, food factories, cosmetics factories, and pharmaceutical manufacturing plants, providing consultation on hygiene management and quality control, as well as contracted testing and inspections. 【Advantages of Outsourcing to Our Company】 ■ Microbial testing of products (products can be sent via courier) ■ Support for the establishment of HACCP systems in food-related facilities ■ Sanitation testing in compliance with HACCP *For more details, please refer to the PDF or feel free to contact us.

• Other Testing Contract
• Other contract services

Our contract research and development services accept development commissions from various companies on themes related to biochemistry and microbiology. We not only engage in product development but also in the development of testing and inspection methods. Even if testing methods have not been established, we will develop suitable testing methods based on our past achievements. 【Advantages of Commissioning Us】 ■ No need to employ full-time researchers ■ No need to purchase specialized development or measurement equipment ■ No need to secure facilities for research and development ■ Development costs are significantly reduced compared to in-house development ■ Fresh proposals that incorporate know-how from different industries are possible *For more details, please refer to the PDF or feel free to contact us.

• Other Testing Contract
• Other contract services

The metabolism of products, along with product development and research and development for that purpose, is essential for corporate growth. However, product development and research and development require significant upfront investments in manpower, development equipment, facilities, etc., making in-house development challenging in the current situation. To avoid the risks associated with in-house development, outsourcing research and development to external research institutions is known as contract research and development. We have obtained licenses for cosmetics manufacturing and sales. 【Examples of Contract Manufacturing】 Soap Toner Emulsion Serum Face masks, etc. *For more details, please download the catalog or contact us.

• Other contract services

Maple Biolaboratories specializes in testing, research, and development using microorganisms, as well as product development utilizing microbial control. We also conduct contract testing for antiviral activity. 【Do you have any of these concerns?】 ■ It is difficult to hire full-time researchers. ■ There is resistance to purchasing non-versatile development and measurement equipment. ■ It is challenging to prepare to secure facilities for research and development. ■ I want to significantly reduce development costs. And more. *For more details, please download our catalog or feel free to contact us.

• Other Testing Contract

Sweat and dirt are removed, leaving the skin clean. Contains argan oil, which is excellent for beauty effects, so the skin is moisturized. Free from preservatives and synthetic surfactants, it does not burden the skin. With 200 mL, it can be used generously for over two months. Contains essential oils, providing a soothing effect.

• others