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We would like to introduce examples of applications of the open architecture "xMAP Technology" in nucleic acid assays. It can be utilized for purposes such as gene expression analysis, miRNA expression analysis, genotyping, gene mutation detection, SNP analysis, CNV analysis, and pathogen detection. Our product allows for various assay formats for different analysis targets to be used in a single system based on MAP technology. 【Examples of Applications (Partial)】 ■ Gene expression analysis ■ miRNA expression analysis ■ Genotyping ■ Gene mutation detection ■ SNP analysis *For more details, please download the PDF or feel free to contact us.
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We would like to introduce examples of applications of the open architecture "xMAP technology" in protein assays. It is utilized for purposes such as epitope mapping, isotyping, enzyme-substrate studies, protein interaction analysis, phosphorylated enzymes, cytokines, and biomarkers. Our product allows for the simultaneous performance and measurement of multiple separate bioassays, as each microbead provides individual detection results. [Examples of Applications (Partial)] ■ Epitope Mapping ■ Isotyping ■ Enzyme-Substrate Studies ■ Protein Interaction Analysis ■ Phosphorylated Enzymes *For more details, please download the PDF or feel free to contact us.
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We would like to introduce examples of the application of the open architecture "xMAP technology" in clinical diagnostics. It is utilized for purposes such as HLA typing for transplantation, detection of autoantibodies, cancer marker testing, virus detection, stratified medicine, companion diagnostics, and therapeutic drug monitoring. This product enables the reduction of time, effort, and costs, as well as the simultaneous measurement of multiple biological assays (multiplexing). 【Examples of Applications (Partial)】 ■ HLA typing for transplantation ■ Detection of autoantibodies ■ Cancer marker testing ■ Virus detection ■ Stratified medicine *For more details, please download the PDF or feel free to contact us.
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Here are some examples of the application of the open architecture "xMAP technology" in drug discovery. It is utilized in compound screening, kinase inhibitor screening, serological studies, toxicity testing, drug metabolism research, receptor-ligand analysis, and vaccine development. Luminex's xMAP system has sold over 20,000 units in 81 countries worldwide and is widely used in various applications. 【Examples of Applications (Partial)】 ■ Compound Screening ■ Kinase Inhibitor Screening ■ Serological Studies ■ Toxicity Testing ■ Drug Metabolism Research *For more details, please download the PDF or feel free to contact us.
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The "xMAP technology" is an open architecture that enables the simultaneous measurement of multiple biological assays, reducing time, effort, and costs. It offers advantages such as reproducibility and allows for the mass production of xMAP microbeads per lot, which was difficult with solid-phase planar arrays, enabling assay standardization. Additionally, it allows for real-time analysis of biological interactions and accurate quantification. 【Advantages】 ■ Speed / High throughput ■ Diversity ■ Accuracy ■ Flexibility ■ Reproducibility *For more details, please download the PDF or feel free to contact us.
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The "xMAP Technology" is an open architecture that enables the simultaneous measurement of multiple biological assays, reducing time, effort, and costs. It offers advantages such as flexibility, allowing for customization to meet individual user needs, and the ability to expand the assay system by adding different microbeads later. Various assay formats for different analytes can be utilized in a single system based on MAP technology. 【Advantages】 ■ Speed / High throughput ■ Diversity ■ Accuracy ■ Flexibility ■ Reproducibility *For more details, please download the PDF or feel free to contact us.
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The "xMAP technology" is an open architecture that enables the simultaneous measurement of multiple biological assays, reducing time, effort, and costs. It offers advantages such as accuracy, allowing for real-time analysis of biological interactions and precise quantification. Additionally, since each microbead provides individual detection results, it is possible to conduct and measure multiple separate bioassays simultaneously. [Advantages] ■ Speed / High throughput ■ Diversity ■ Accuracy ■ Flexibility ■ Reproducibility *For more details, please download the PDF or feel free to contact us.
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"xMAP Technology" is an open architecture that enables the simultaneous measurement of multiple biological assays, reducing time, effort, and costs. It offers advantages such as diversity, allowing various assay formats for different analytes to be utilized in a single system based on MAP technology. In other words, it can perform analyses of nucleic acid reactions, antigen-antibody reactions, enzymes, receptor-ligand interactions, and other protein interactions all in one device. 【Advantages】 ■ Speed / High throughput ■ Diversity ■ Accuracy ■ Flexibility ■ Reproducibility *For more details, please download the PDF or feel free to contact us.
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The "xMAP technology" is an open architecture that enables the simultaneous measurement of multiple biological assays, reducing time, effort, and costs. With advantages such as speed and high throughput, each microbead provides individual detection results, allowing for the simultaneous execution and analysis of various separate bioassays. Additionally, Luminex stains microbeads with fluorescent dyes that are precisely concentration-set, offering a set of beads in up to 500 different colors. [Advantages] ■ Speed / High Throughput ■ Diversity ■ Accuracy ■ Flexibility ■ Reproducibility *For more details, please download the PDF or feel free to contact us.
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The "xMAP technology" is an open architecture that enables the simultaneous measurement of multiple biological assays, reducing time, effort, and costs. In the system used with this product, assay reactions are performed on the surface of each color-coded microbead, and the results are read individually by an analyzer. Additionally, the analyzer uses multiple wavelength lasers and LEDs along with a high-speed digital signal processor to read the reactions occurring on each microbead as results of multiplex assays. 【Advantages】 ■ Speed / High throughput ■ Diversity ■ Accuracy ■ Flexibility ■ Reproducibility *For more details, please download the PDF or feel free to contact us.
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MagPlex-Avidin Microspheres are magnetic microbeads coated with avidin on their surface. Similar to avidin-coated ELISA plates, they serve as a substrate for immunoassays by reacting with biotinylated ligands such as peptides. These beads are encoded with dye staining, and these regions are identified by the xMAP system, allowing for the detection of up to 100 different analytes from a single sample.
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MagPlex Monitoring Microspheres are magnetic polystyrene beads that help monitor the performance of assays and systems. By using MagPlex Monitoring Microspheres, you can investigate factors that affect the target fluorescence values, such as system variability and user errors. There are two types of MagPlex Monitoring Microspheres: the MagPlex RP1 Monitor, which emits fluorescence detected by the RP1 channel of all xMAP systems, and the MagPlex RP2 Monitor, which emits fluorescence detected by the RP2 channel of the xMAP INTELLIFLEX DR-SE system.
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xMAP INTELLIFLEX is a compact flow-based multiplex platform equipped with the latest features of the proven xMAP technology. It offers two models: the xMAP INTELLIFLEX system and the xMAP INTELLIFLEX DR-SE system. The xMAP INTELLIFLEX DR-SE system includes a second reporter channel, allowing for the selection of dual reporter mode. It enhances performance, strongly supports assay development, and simplifies the user experience. It combines rapid results from low to high plex, along with the capability to simultaneously acquire data for two parameters per analyte.
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Unique 24-base DNA sequence anti-TAG is covalently bonded to the surface of MagPlex-TAG microspheres. By adding a complementary TAG sequence to the primers or probes of the target nucleic acid sequence, custom bead arrays can be created. Luminex microbeads are widely used in various xMAP bioassay systems. MagPlex-TAG is prepared at a concentration of 2.5 x 10^6 beads/mL and is provided in a 1 mL volume. For other volumes, please contact Luminex.
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MicroPlex Microspheres (MicroPlex) are prepared at a concentration of 12.5 x 10^6 particles/mL and can be ordered in vial sizes of 1 mL, 4 mL, and 16 mL. For other volumes, please contact Luminex. These microbeads are the reagents necessary for building xMAP bioassays. Important: MicroPlex is not compatible with the MAGPIX system.
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MagPlex Microspheres (MagPlex) have several advantages over traditional MicroPlex Microspheres. Because MagPlex is magnetic, it can be quickly and easily separated from solutions using a magnetic separator. This improves recovery rates during dispensing and washing processes and facilitates assay automation. Additionally, MagPlex offers 500 types of regions, allowing for the construction of assays that can detect up to 500 items in a single well. MagPlex is compatible with all four types of xMAP systems. The MAGPIX system is a simple, user-friendly, and compact Luminex device, and MagPlex can be used in combination with this system. These microbeads are the necessary reagents for constructing xMAP bioassays.
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The MAGPIX system is the simplest, low-cost, and compact option within the Luminex xMAP systems. This system's compact multiplex simultaneous measurement unit can measure up to 50 analytes present in a single well's reaction solution and can read a 96-well plate in 60 minutes. The MAGPIX system features an automatic cleaning routine and is compatible with magnetic beads (MagPlex Microspheres), making it an easy-to-learn and user-friendly system. (Medical device manufacturing and sales notification number 11B1X10017000014)
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The FLEXMAP 3D system is the most advanced and versatile multiplex platform from Luminex. FLEXMAP 3D offers rapid reading performance and compatibility with both 96-well and 384-well plates, making it an ideal platform for high-throughput applications due to its ease of integration with front-end automation systems. This system can utilize both magnetic and non-magnetic microbeads, allowing for the simultaneous measurement of up to 500 types of genes or proteins from small sample volumes. With the ability to automate startup, shutdown, and cleaning routines, FLEXMAP 3D is user-friendly and requires minimal effort.
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The Luminex 100/200 system has become the standard for multiplex analysis. With over 11,000 units sold worldwide, it offers more than 50 assays that have received FDA 510(k) clearance. It is capable of measuring up to 100 items from small samples in microplates, and because it can use both magnetic beads and polystyrene beads, this system is ideal for use in labs that require flexibility. The Luminex 100/200 system can read one 96-well plate in 45 minutes, providing very high sample throughput. (Medical device manufacturing and sales notification number: 11B1X10017000005)
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