ライフィクスアナリティカル List of Products and Services

This catalog introduces the products handled by Nanion Technologies Japan, the Japanese subsidiary of a manufacturer of analysis devices for basic and drug discovery research. We offer a lineup that includes low, medium, and high-throughput automated patch clamp systems, as well as iPS-derived cardiomyocyte measurement systems. Additionally, we provide information on the target users, including pharmaceutical companies. [Contents (excerpt)] ■ Nanion Technologies Japan ■ Automated Patch Clamp Systems ■ Target Users ■ Automated Patch Clamp and Manual Patch Clamp ■ Port-a-Patch mini *For more details, please refer to the PDF document or feel free to contact us.

"UNAGI" is a completely hands-free benchtop buffer exchange solution. Simply place 1 to 8 samples into the dedicated sample container "Una" and set it in the holder to complete the preparation. It can handle samples ranging from 0.5 to 8 mL each. The software for this product is very easy to operate. Once the operation starts, you can leave the product and check the status at your convenience. 【Features】 ■ Completely hands-free, no need to stay in the laboratory ■ Simultaneous processing of up to 8 samples ■ Achieves a recovery rate of over 96% ■ Capable of concentrating samples within a usable range ■ Records everything that happens during operation and can generate detailed reports *For more details, please refer to the PDF materials or feel free to contact us.

Are you spending a lot of time and effort on buffer exchange and concentration tasks? 'UNAGI' adopts a complete Walk-Away system. Setup takes only 15 minutes, and it is a device that can simultaneously process the exchange and concentration of 8 samples. We also offer the high-throughput model "Big Tuna," which is capable of automation, so please feel free to contact us. 【Features】 ■ Complete Walk-Away system ■ Setup takes only 15 minutes ■ Simultaneous processing of exchange and concentration for 8 samples ■ Fully automatic buffer exchange and concentration device ■ Simple and easy-to-understand screen operation *For more details, please refer to the PDF document or feel free to contact us.

This catalog introduces the "Electrophysiology Experimental Equipment" from Nanion Technologies Japan, Inc. We proudly present the Auto Patch Clamp System, which boasts data quality from Gigaseal and enables simultaneous measurement of 384 cells, along with lipid bilayer experimental devices that make recording single-channel currents easy. Additionally, we offer liposome production devices and iPS-derived cardiomyocyte measurement devices. Please make use of this information for your product selection. [Contents] ■ Auto Patch Clamp System ■ Lipid Bilayer Experimental Device ■ Liposome Production Device ■ Transporter Activity Measurement Device ■ iPS-Derived Cardiomyocyte Measurement Device *For more details, please refer to the PDF materials or feel free to contact us.

"WELLJET" is designed to provide an excellent user experience and flexibility for applications that require low-cost and accurate reagent dispensing. Both models feature a groundbreaking dispensing cassette (EasySnap), which keeps running costs low and is easy to handle. They enable high-speed microplate dispensing to improve laboratory throughput. The user interface, equipped with a high-resolution large touchscreen, allows for intuitive and easy programming. 【WELLJET Dispenser Features】 ■ Dispensing cassette technology keeps running costs low and installation is very simple ■ Capable of dispensing into plates with up to 1536 wells or deep well plates ■ Large display facilitates easy programming and operation ■ Intuitive user interface ■ Small footprint, effectively utilizing valuable workspace *For more details, please refer to the PDF document or feel free to contact us.

The powder friction charge measurement device "GRANUCHARGE" automatically and accurately measures the amount of charge generated in powders as they move in contact with selected equipment materials (such as SUS). This product measures the charged and falling powder using a Faraday cup as it passes through a vibrating cylinder. By understanding the charging characteristics of the powder, you can confirm the effectiveness of countermeasures. We will be exhibiting at the "International Powder Technology Exhibition Tokyo 2022," which will be held from December 7, 2022 (Wednesday)! *The exhibits are expected to include the dynamic angle of repose measurement device "GRANUDRUM" and the powder flowability analysis device powder rheometer "FT4." ■Venue: Tokyo Big Sight, East Hall 1 ■Booth Number: 1A-08 For more details, please refer to the PDF document or feel free to contact us. We look forward to seeing you at the exhibition.

"Big Tuna" is a product that automates the buffer exchange for the formulation, concentration, and residue treatment of gene therapy vectors such as proteins, AAV, LNP, and VLP, with a setup time of just 30 minutes. We offer two types of plate-based filters that can simultaneously exchange and concentrate 24 or 96 samples. The Unfilter 96 can exchange a minimum volume of up to 100μL with a maximum of 96 samples at a time. Additionally, the Unfilter 24 accommodates larger volumes, allowing for the exchange of up to 8mL with a maximum of 24 samples. Various options for molecular weight cut-off are also available, enabling the use of the most suitable Unfilter for your work. 【Features】 ■ Frees you from manual buffer exchange ■ Supports a wide range of sample numbers and volumes ■ Processes at an appropriate buffer exchange rate ■ Easy to set conditions *For more details, please refer to the PDF document or feel free to contact us.

The "Honeybun" we handle is a high-speed viscometer that can output data almost simultaneously with processing. Regardless of whether the number of samples is 1 or 10, it uses a few microliters of each sample through a microchannel and reads viscosity in the range of 0.5-150 cP within a few minutes. You can either input all the details of the samples according to your preference or have all the information automatically entered into the product's software with a simple input for measurement. Setting up the experiment can be completed in just three clicks, allowing you to collect data immediately. 【Features】 - Accelerated viscosity data - Can measure up to 150 cP - Measurement in 1 minute (for values below 10 cP) - Applicable under various conditions - Can measure at various temperatures *For more details, please refer to the PDF document or feel free to contact us.

"Lunatic" is a product that allows for the easy simultaneous quantification of proteins, DNA, and RNA, measuring up to 96 samples in just 10 minutes. It is possible to measure high-concentration samples without dilution. Accurate UV/Vis quantification of biopharmaceuticals and genomic products can be performed every time. No sample pretreatment or cleaning is required, and there is no need to worry about cross-contamination or evaporation, as samples remain stable for up to 2 hours. 【Features】 ■ No cumbersome workflow required ■ Maximizes the use of biopharmaceuticals ■ Exceptionally superior data ■ Overwhelming accuracy ■ Compatible with downstream processes ■ Comprehensive audit trail *For more details, please refer to the PDF document or feel free to contact us.

"Stunner" is a system that allows simultaneous acquisition of UV/Vis concentration, dynamic light scattering (DLS), and static light scattering (SLS) data from a 2μL identical sample. It enables detailed investigation of AAV to measure total capsid titer and Empty/Full ratio, as well as to obtain payload concentration and size data for any nanoparticles all at once. It is possible to analyze concentration, hydrodynamic size, polydispersity, and the presence of aggregates collectively, allowing for the assessment of protein quality, and you can instantly determine whether your AAV, nanoparticles, or proteins are suitable for your purposes. 【Features】 ■ More information from a small amount of sample ■ Detailed analysis of AAV ■ Supports large-scale nanoparticle size measurements ■ Remarkably excellent data ■ Compatible with downstream applications *For more details, please refer to the PDF document or feel free to contact us.

"Leprechaun" is a system that allows for the examination of viral titer by checking whether the lentivirus particles are of the correct size and structure. By capturing the surface proteins of exosomes and measuring their size, and confirming with fluorescence, the concentration of exosomes can be quickly measured, ensuring the presence of the correct proteins. Additionally, depending on the situation, it is possible to customize the assay using the Flex kit with unique capture antibodies or detection antibodies. 【Features】 ■ Can reveal the characteristics of vectors such as lentiviruses and exosomes for up to 16 samples at once. ■ Captures vectors in a sample tray, Luni, from 1 to 25 μL, measures their size, and then identifies the structure of each particle using immunofluorescence measurement. ■ Results can be obtained in just a few hours. *For more details, please refer to the PDF document or feel free to contact us.

The 『heliX』 is a high-sensitivity molecular interaction analysis device based on the switchSENSE principle. It accurately detects slow dissociation in high-affinity interactions and fast dissociation in weak interactions. Stable and accurate data acquisition is possible even during prolonged dissociation. Additionally, it can accurately evaluate the cooperativity of binding to two targets, such as bispecific antibodies and PROTACs. Please feel free to contact us if you have any inquiries. 【Features】 ■ Detection of up to 4 signals at 2 spots ■ Flexible control of ligand density ■ High-sensitivity molecular interaction analysis ■ Accurate detection of very rapid signal changes ■ Analysis of dual specificity molecular interactions *For more details, please refer to the PDF document or feel free to contact us.

"heliXcyto" enables the automatic analysis of binding constants (affinity, avidity) while maintaining the complexity of biological systems by directly measuring the kinetics of molecular binding and dissociation on the cell surface. The newly designed cellTRAP biochip, equipped with a cage made of biocompatible polymer, allows for the capture of various types of single cells on the chip and enables real-time interaction measurement (RT-IC) on the cell surface. 【Features】 ■ Fully automated workflow ■ Compatible with various cells (live cells and fixed cells) ■ Supports various complex media ■ Analysis of single cells and multiple cells ■ Analysis at low membrane protein expression levels ■ Ultra-high sensitivity fluorescence detection *For more details, please refer to the PDF document or feel free to contact us.

"NanoLab 3D" is a compact and user-friendly dynamic light scattering (DLS) measurement device. It accurately measures particle size distribution even in high-concentration samples. The modulated three-dimensional cross-correlation technology efficiently suppresses multiple scattering. Sample dilution is unnecessary even for highly turbid samples. It offers the highest level of measurement resolution and sensitivity among commercially available DLS devices, thanks to research-grade photonic technology and advanced CORENN algorithms. [Features] ■ Minimum 4μL ■ Measurement within 30 seconds ■ Fully automated workflow ■ Support from a team of experts *For more details, please refer to the PDF document or feel free to contact us.

"Prevelex AP1" is a product with a unique hydrophilic polymer that can be coated onto various substrates. It achieves a high adsorption suppression effect against biomaterials such as antibodies, peptides, and viruses. It suppresses nonspecific adsorption of low-concentration samples to plastic containers, thereby improving analytical accuracy. Additionally, we can provide custom coating for the experimental equipment used by your company. 【Product Lineup】 ■ Microtubes ■ Screw vials ■ LC-MS vials ■ Tube plates *For more details, please refer to the PDF document or feel free to contact us.

"Prevelex AP2" is a product with a unique hydrophilic polymer that can be coated onto various substrates. It achieves a high adsorption suppression effect against biomaterials such as antibodies, peptides, and viruses. Additionally, it has been confirmed to reduce elution and has organic solvent resistance through proprietary technology. We also offer custom coating for the experimental equipment used by your company. Please feel free to contact us when needed. 【Product Lineup】 ■ Microtubes ■ Screw vials ■ LC-MS vials ■ Tube plates *For more details, please refer to the PDF materials or feel free to contact us.

The microscopic Raman spectroscopy sensor "Raman EYE" is designed to be attached to an upright microscope, where it uses a laser to illuminate a sample and examines the state and type of the material from the resulting Raman scattered light. It is used for non-contact and non-destructive evaluations, such as crystallinity assessment, molecular structure analysis, and residual stress analysis. It is expected to be utilized as software for proposing new material development and for plant full automation. 【Features】 ■ Easy attachment to the microscope in one minute ■ Remote operation using a smartphone is possible ■ Achieves one of the smallest sizes in the world ■ Automatic analysis using generative AI ■ Material development can be conducted starting from around 3 million yen *For more details, please refer to the PDF document or feel free to contact us.

The flagship charge photometry "illumionONE" is a technology that directly measures the process in which individual particles exhibit their functions during charging and discharging through imaging. It visualizes the electrodes during battery operation, allowing for the capture of localized changes in charging state and morphology at the resolution of single particles! It is possible to observe how much material is activated, where performance is lost, and to discover factors that limit charging performance at the active particle level, making it applicable to lithium-ion and other chemical substances. 【Features】 ■ Direct observation of particles during charging and discharging using an optical microscope ■ Benchtop design allows for measurements in the laboratory ■ Fully integrated electrochemical control *For more details, please download the PDF or contact us directly.