日本ビュッヒ List of Products and Services

The "NIRFlex N-500" is a near-infrared analyzer that employs the same optical system with excellent stability. It is well-suited for use in laboratories and offers various measurement options. With its highly expandable modular design, measurement options can be added at any time as needed. 【Features】 ■ Certified model by the Ministry of Agriculture, Forestry and Fisheries ■ Ideal for use in laboratories and quality control rooms ■ Highly expandable modular design ■ Measurement modules can be easily exchanged ■ Each module is automatically recognized by the software and can be used immediately after replacement *For more details, please refer to the PDF document or feel free to contact us.

Spray drying is an ideal drying process that transforms liquid materials (aqueous solutions, emulsions, slurries, pastes, molten liquids) into dry powder in a single step. The sample liquid is sprayed from a nozzle into high-temperature drying gas. It is widely used in fields such as pharmaceuticals, healthcare, nutrition, and biotherapy, with representative applications including "powder for treating lung diseases," "microencapsulation," and "spray drying of heat-sensitive vaccines." ■ For more details, please refer to the catalog. If you would like more detailed data, please contact us.

Spray drying is an attractive continuous process that transforms liquids (solutions, emulsions, slurries, pastes, or melts) into micron-sized particles, allowing for adjustments in spray volume, shape, porosity, concentration, and chemical composition. It is widely used in fields such as materials, chemicals, food, and pharmaceuticals. Typical applications include: ■ Coatings (titania, alumina, zirconia, yttria coatings) ■ Advanced ceramics (such as new superconducting ceramics) ■ Toners and magnetic tapes ■ Inhalable dry powders ■ Nanoparticle drugs, among others. *For more details, please refer to the catalog or contact us.

Spray drying is an attractive continuous process that transforms liquids (solutions, emulsions, suspensions, slurries, pastes, or melts) into micron-sized particles, allowing for adjustments in spray volume, shape, porosity, concentration, and chemical composition. It is used in fields such as food, pharmaceuticals, chemicals, and materials. Typical applications include: - Encapsulation of oils - Efficient use of pharmaceuticals - Protecting sensitive products by encapsulating them in a carrier - Encapsulating expensive products in inexpensive carriers to facilitate handling and formulation, among others. *For more details, please refer to the catalog.

What is needed for innovation is to realize a vision. Büchi has demonstrated this concept over the past few decades through innovative products in the field of evaporation and separation. As a result of the continuous development of experimental methods and technologies, we have been able to complete this revised edition of the "Laboratory Assistant." This book will help provide a broader and deeper understanding of widely used laboratory equipment such as rotary evaporators, vacuum pumps, and melting point measurement devices. All the equipment illustrated in this book is Büchi's products. Each chapter of this book is written using general expressions to apply as much as possible to products from other companies. We hope that readers will find the content of the "Laboratory Assistant" interesting and that it will help solve challenging issues in the laboratory. We encourage you to have this book at hand.

The Kjeldaire Decomposer K-446/K-449 reduces processing time by up to 2 hours and meets the highest safety requirements. Combined with the KjelMaster (Kelsampler) system, an all-automatic distillation device featuring Bühler's original sample transfer structure, further efficiency can be achieved. The exhaust unit is magnetically fixed for exceptional ease of use, and the drip tray extends the lifespan of the heating block and accessories. The latest sealing system enables efficient steam suction. 【Features】 ○ High efficiency ○ Reduces processing time by up to 2 hours ○ Easy to handle and safe ○ Proven high performance: compliant with many official methods For more details, please contact us.

The Kjeldaahl Digester K-439 (IR type) is an IR digester equipped with a temperature controller that allows for precise temperature settings. It can be programmed for temperature gradients and time, with the ability to save data in a database. It features an easy-to-read LCD display that allows you to monitor the progress of the digestion. Acidic vapors, reactive gases, and odors generated during the Kjeldaahl analysis process can be safely handled by the Scrubber B-414. Additionally, it prevents corrosion from drafts caused by acids. 【Features】 - Efficient operation - Accurate and stable temperature control - Easy-to-read LCD display - Selectable sample test tubes - Prevention of acidic vapor leaks For more details, please contact us.

The B-440 is a wet ashing device composed of a wet decomposer and a scrubber. It allows for easy and efficient ashing treatment tests, such as the determination of residue by incineration in the pharmaceutical field and pretreatment for heavy metal measurement in the food sector. Each program can be set with up to five stages of time and temperature, and it uses halogen lamps, allowing it to quickly reach the set temperature and begin heating. 【Features】 - Quick temperature rise due to the use of halogen lamps - Ability to set 9 different programs - Each program can have up to five stages of time and temperature settings - Reduction of bumping - Visual observation of the sample condition through a glass hood *For more details, please refer to the PDF document or feel free to contact us.

The "Multi Vapor P-6/P-12" is a multi-sample parallel evaporator that can process up to 12 samples simultaneously. It can utilize the vacuum system and solvent recovery apparatus of your existing rotary evaporator. Depending on your application, you can choose between the Multi Vapor and the rotary evaporator. You can select either the "6-sample type" or the "12-sample type" based on the sample volume and container size. 【Features】 ■ Enables fast evaporation without hassle ■ The installation space required is only 27×40 cm, making it space-saving ■ No need to transfer samples ■ Significantly improves work efficiency ■ Safely recovers vaporized solvents through cooling condensation *For more details, please refer to the PDF document or feel free to contact us.

◆◇◆ Lineup ◆◇◆ ◆M-560 Basic type model for visual measurement - A model dedicated to visual measurement of melting and boiling points, an attractive priced melting point measurement device - Suitable for laboratories that require only visual measurement and have a relatively small number of sample specimens - Equipped with a bright and large magnifying lens - Visual measurement of melting and boiling points - Frequency display for boiling point measurement - Temperature calibration SOP function included (calibration with 4 types of reference materials) - Fast heating and cooling rates - Wide temperature range from room temperature to 400°C - Simultaneous measurement of 3 samples possible - Supports IQ/OQ/validation/tracability (optional) - Complies with the Japanese Pharmacopoeia General Rule 13, and adheres to pharmacopoeias such as EP (European Pharmacopoeia) and USP (United States Pharmacopeia)

Products with groundbreaking features are emerging one after another, such as yogurt containing beneficial bacteria that reach the intestines, fabric softeners that release a stronger fragrance when moved, facial cleansers infused with anti-aging ingredients, and oral medications with long-lasting effects. The technology of "microencapsulation" plays a significant role in this development. The 'B-390/B-395 Pro' is a device that instantly produces uniform, spherical capsules ranging from 0.15 to 2 mm, using materials such as alginates, gelatin, and fats as membranes. Inside the capsules, various components such as enzymes, drugs, cells, microorganisms, flavors, fragrances, oils, and vitamins are encapsulated, allowing for efficient development research to control dissolution time and locations. It is used for adjusting the components and functions of pharmaceuticals, foods, cosmetics, and more. ★ Currently, we are offering a free explanation of encapsulation technology and a collection of application examples for various industries! 【Applications】 - <Pharmaceuticals> Drug delivery systems that deliver active ingredients to specific locations - <Food> Enhancing the value of food materials by mixing multiple components - <Biological Research> Cell transplantation through the encapsulation of animal cells - <Cosmetics> Encapsulation of odor components, etc.

The "B390/B395 Pro" is a encapsulation device that uses polymers such as gelatin, pectin, and alginates to create extremely small capsules ranging from 0.15 to 2 mm. The capsules can encapsulate various components such as enzymes, drugs, cells, microorganisms, flavors, aromas, oils, and vitamins, allowing for stabilization and protection of the ingredients. Through controlled release, it is also possible to manage the dissolution time and release points of the components. It can produce up to 6000 capsules per second and is used for adjusting the components and functions of pharmaceuticals, food, cosmetics, and more. 【Applications】 - <Pharmaceuticals> Drug delivery systems that deliver components to specific locations - <Food> Enhancing the value of food materials by mixing multiple components - <Biological Research> Cell transplantation through the encapsulation of animal cells - <Cosmetics> Encapsulation of fragrance components and more *For more details, please download the catalog or contact us.

The "R-220 Pro" is a large-capacity evaporator packed with user-friendly features suitable for pilot plants and kilo labs. The sample introduction valve allows for easy sample introduction without removing the flask. If the sample volume exceeds what can fit in the flask at once, additional samples can be easily introduced during distillation. Furthermore, it features an easy-to-use large-screen touch panel. It includes a database function that allows for easy setting of optimal vacuum levels for each solvent, as well as the ability to check operational status remotely via mobile devices, making it a model focused on usability. 【Features】 ■ Easy-to-read large screen / Touch panel operation ■ Database function for easily setting optimal vacuum levels for each solvent ■ Ability to check operational status remotely via mobile devices ■ Push notifications to the device in case of errors ■ Programmable time settings for rotation speed, bath temperature, and vacuum level ■ Capability to save operational status to an SD card for process management ■ Leak test function *For more details, please refer to the PDF materials or feel free to contact us.

The B-585 is a compact drying device designed with a space-saving design that pursues diverse possibilities in the lab. It is suitable for drying very small to small samples and quickly transitioning to reproducible analysis. With optional units, it can perform drying, distillation, sublimation, and freeze-drying all in one device. 【Features】 - Compact space-saving design - Capable of drying, distillation, sublimation, and freeze-drying in one unit - Transparent structure allows for visual confirmation of samples - Fast heating rate - Three-step program settings based on temperature and time (control of the vacuum pump's power On/Off is also possible) *For more details, please refer to the PDF document or feel free to contact us.

The "E-800" is a multi-sock extraction device designed to perfectly meet any customer's requirements. Each of the six units can be set with individual extraction conditions and methods. By adopting a high-speed heater and combining it with advanced extraction process control functions, we have achieved high-precision reproducibility. 【Features】 ■ Suitable sample amount ■ High-performance condenser ■ Complete visualization ■ Extract protection sensor ■ Flexible applications *For more details, please refer to the PDF materials or feel free to contact us.

The "FlashPure Series" is a cartridge column for flash purification that meets various needs with a rich lineup. We offer a wide range from low-cost types to high-end types focused on separation capability, with various sizes, stationary phases, particle sizes, and packing material types available. ★ A campaign is currently underway until March 2024! Be sure to take advantage of this opportunity♪ 【Campaign Target Products (Excerpt)】 ■ High-performance flash cartridges ▶ FlashPure EcoFlex Silica 12g x 18 pieces ▶ FlashPure EcoFlex Silica 25g x 12 pieces ■ Economical flash cartridges ▶ Flash Pure Select Silica 12g x 18 pieces ▶ Flash Pure Select Silica 25g x 12 pieces

Introducing the "Soxhlet Extraction Device" handled by Nippon Buech. This device achieves extraction tailored to the sample through program settings. It shortens the time for one cycle using a solvent light sensor and solenoid valve. Additionally, it can operate automatically until drying is complete. 【Features】 ■ Fast, easy, and reliable ■ Achieves time reduction for one cycle with solvent light sensor and solenoid valve ■ Realizes extraction according to the sample through program settings ■ Capable of automatic operation until drying is complete ■ Equipped with safety features such as prevention of solvent drying and detection of solvent leakage *For more details, please refer to the PDF document or feel free to contact us.

This document introduces application examples using the tabletop freeze dryer "Lyovapor L-200 series" for laboratories. It includes procedures, results, and discussions on freeze-drying foods such as bananas and truffles, mannitol used in pharmaceuticals, and traditional Chinese herbal decoctions. Photos of the appearance before and after freeze-drying, as well as tables of moisture content, are also included. 【Benefits of Freeze-Drying】 ■ Preserves nutrients sensitive to odor, taste, and temperature changes ■ Avoids surface hardening ■ Can be stored for long periods at room temperature ■ Easily reversible through rehydration ■ No need to add additives during the process *You can view an excerpt of the document from the "PDF Download." If you would like the complete version, please feel free to contact us.

This poster introduces tips on how to shorten the working time involved in "freeze-drying" while ensuring it is done "reliably." It includes topics such as "the freeze-drying process," "effective process control," "requirements for vacuum pumps," and "detection of the end point of drying." We encourage you to take a look. 【Contents (partial)】 ■ Shortening experimental work time through optimization of process parameters ■ Effective process control ■ Cooling condenser ■ Requirements for vacuum pumps ■ Correlation between temperature and vapor pressure of ice *For more details, please refer to the PDF document or feel free to contact us.

Related Device: Fractionation Chromatography System Pure C-815 Cholesterol and its esters, which are components of biological membranes, are utilized as industrial raw materials in cosmetics, pharmaceuticals, and liquid crystals. When performing gradient fractionation purification for compounds that are difficult to detect with UV detectors, methods are selected using low wavelength UV detection such as 210 nm or ELSD (Evaporative Light Scattering Detector). ELSD is a fractionation purification method that overcomes the disadvantages of UV-triggered fractionation due to the absence of baseline drift and T0 peaks. By adopting ELSD & UV double triggering, it enables complementary fractionation purification using both ELSD and UV. 【Issues with Low Wavelength UV Triggered Fractionation】 ■ The baseline drifts due to the solvent's own absorption used in the mobile phase, making it difficult to detect sample peaks. ■ Baseline rises consistently during gradient steps, leading to the baseline being recognized as a peak, which significantly increases purification time and fraction volume. *For more details, please refer to the PDF document or feel free to contact us.

Related Products: Fractionation Chromatography System Pure C-815 To achieve high-purity precision purification of mid-sized compounds such as peptides, reverse phase LC is commonly applied, and simple rough purification after synthesis or extraction is generally performed using methods like SPE (solid-phase extraction). In rough purification using SPE, adjusting the pH of the solvent allows for easy separation of anions, cations, and non-ions, but separating components of the same ionic type is challenging. Rough purification by flash chromatography enables selective and rapid separation and purification of target compounds through optimization of mobile phase and gradient conditions. 【Mechanism of Rough Purification by SPE】 ■ Easy separation of anions, cations, and non-ions ■ Difficult separation of components of the same ionic type (anions, cations, non-ions) *For more details, please refer to the PDF document or feel free to contact us.

There are many available distillation systems. You may be unsure which one is suitable for achieving your goals. This free guide we provide will help you find a system that fits your samples, applications, and needs. Should you choose an industrial or lab evaporator, a multi-sample parallel evaporator, or a glass tube oven? Refer to the guide to determine which is appropriate for the following applications: - Research and development, production, bars & restaurants, natural product exploration, or contract labs - Various batch sizes and flask sizes - Foaming samples or light-sensitive samples - Options for automation or digitalization Make sure you are using a system that is suitable for your methods to enhance the efficiency and safety of your lab. *For more details, please refer to the PDF materials or feel free to contact us.*

In the compound feed industry, various products with different ingredient formulations are produced, and even a single factory manufactures a wide range of products for different types of animals and pets, as well as custom formulations. In the production process of compound feed, maximizing profits is a significant challenge, particularly due to factors such as narrow profit margins, pressure from delivery times and costs, variability in raw material quality, and high quality demands. This document outlines five steps to achieve a compound feed process line that maximizes profits. We encourage you to read it. 【Contents】 ■ Problem Recognition ■ Analysis of the Production Process ■ Pursuit of Optimization ■ Discovery of Solutions ■ Implementation of Real-Time Process Control with NIR-Online Sensors *For more details, please refer to the PDF document or feel free to contact us.

The "Kjeldahl method" is a rapid and highly accurate and reproducible method for analyzing nitrogen and protein. Büchi offers systems tailored to various needs of Kjeldahl analysis, ranging from simple distillation units to advanced distillation and titration analysis equipment. Our devices are designed to operate in accordance with methods such as AOAC, EPA, ISO, and DIN, and accommodate various anticipated applications, including the Devalta method and accessories for Kjeldahl digestion that allow for the addition of hydrogen peroxide. [Key elements of Büchi's solutions using the Kjeldahl method] ■ A package that integrates the workflow ■ A wide range of products ■ Accessories tailored to specific applications ■ Support and technical expertise *For more details, please refer to the PDF materials or feel free to contact us.

This pocket guide explains the basic knowledge of the Kjeldahl method, incorporating theory and tips. • Are you familiar with the reaction equation of the Kjeldahl method? • How do you determine the measurement conditions? • Are you aware of different techniques such as boric acid titration and back titration? Additionally, it covers all steps of nitrogen and protein analysis, summarizing key points concisely. Please make use of it in your lab! 【Contents (partial)】 ■ Overview of the Kjeldahl process ■ Sample pretreatment - Overview ■ Sample pretreatment ■ Digestion - Overview ■ Digestion - Carbonization *For more details, please refer to the PDF document or feel free to contact us.

This free guidebook explains the equipment and procedures used for matrix analysis of soil, sludge, sediments, waste, wastewater, and air. It can be utilized for tips to improve workflow, productivity, and quality in the lab. Please refer to it for the detection of common contaminants such as PAHs, PCBs, TPHs, phthalates, and pesticides. [Contents] ■ Outstanding solutions capable of handling a wide variety of matrices ■ Dedicated solutions tailored to the value chain ■ Suitable solutions customized to specific needs ■ Workflow for contaminant analysis *For more details, please refer to the PDF document or feel free to contact us.

The Pure series is a space-saving, smartly designed preparative chromatography system. Some models are equipped with an ELSD that does not miss peaks even with samples that have no UV absorption. Standard features include mobile phase residual, waste liquid, and solvent leak sensors. *Excluding C-805. The operation is simple, allowing for separation condition settings, control, and monitoring on a single screen. Parameters can be changed even during preparative purification. 【Features】 ■ Space-saving design ■ By using a solvent container stand, the mobile phase can be positioned at the top of the device ■ High safety ■ The fraction collector's door and ventilation system prevent exposure to solvent vapors ■ Simple operability *For more details, please download the PDF or feel free to contact us.

The "Pure C-900" is an entry-level preparative chromatography model suitable for first-time flash chromatography. The connected devices are automatically recognized due to its modular design, allowing for flexible combinations of peripheral equipment based on application and budget. The time required for preparative purification is about 1/5 that of using an open column, saving both effort and time. Would you like to significantly improve the efficiency of your preparative purification? 【Features】 ■ Easy connection ■ Convenient pre-packed cartridges ■ Reduces consumption and exposure to organic solvents ■ Increased speed and reproducibility with pump-driven liquid delivery and two-solvent gradient elution ■ Powerful pump with a maximum flow rate of 300 mL/min and pressure resistance of 50 bar (5 MPa) ■ UV (254, 275, 325, 365 nm fixed four wavelengths) trigger detects peak elution and automatically collects fractions *For more details, please download the PDF or feel free to contact us.

We offer cartridge-type columns suitable for flash chromatography. In addition to the FlashPure series filled with silica, C18, as well as amino and diol stationary phases, we have newly started selling Pure+Flash. Furthermore, our PrepPure columns for preparative HPLC and SFC feature unique selectivity for polar and non-polar, chiral and achiral compounds, with chemically bonded silica, as well as a lineup of coated or immobilized polysaccharides. 【Product Lineup】 ■ Cartridge columns for flash chromatography ・Pure+Flash ・FlashPure ■ Columns for preparative HPLC and SFC ・General-purpose columns ・Chiral separation columns *For more details, please download the PDF or feel free to contact us.

"NIR-Online" is a process-type near-infrared (NIR) analyzer that measures the parameters necessary for product quality and manufacturing management in real time. It can output quantitative values for various parameters, from component content to physical property values, non-contact and non-destructively, at intervals of a few seconds for the manufactured products. It is adaptable to a wide range of industrial fields such as food, feed, and chemicals, allowing for continuous monitoring of all processes from raw material acceptance to final product shipment. For example, it can quickly implement feedback necessary for manufacturing management, such as "confirming changes in product quality" or "determining the start and end of processes." 【Features】 ● Compatible with various manufactured products such as powders, granules, ground materials, pastes, and liquids ● Continuously measures multiple quality control items in real time ● Supports various installation forms such as piping and conveyors ● Automatically detects the manufactured product and starts measurement ● Equipped with temperature control functions to handle high-temperature environments *For more details, please download the PDF or feel free to contact us.

Büchi Japan Co., Ltd. will be exhibiting at "JASIS Kansai 2025," held at Grand Cube Osaka. We plan to showcase five products: "Kjeldahl Distillation Unit K-365Pro," "Melting Point Measurement Device M-565," "Near Infrared Analyzer NIRFlexN-500," "Near Infrared Analyzer for Manufacturing Processes NIR-Online," and "Rotary Evaporator R-300." We kindly invite you to visit our booth. 【Event Overview】 ■ Dates: January 29 (Wed) to January 31 (Fri), 2025, 10:00 AM to 5:00 PM ■ Venue: Grand Cube Osaka (Osaka International Convention Center) ■ Büchi Japan Booth: D-03 *For more details, please download the PDF or feel free to contact us.

Büchi Japan Co., Ltd. will hold the "Near Infrared Analysis Seminar in Osaka" at the NLC Shin-Osaka Building. The near-infrared (NIR) analysis method allows for rapid component analysis without sample pretreatment and is being adopted in a wide range of fields, including food, chemicals, and pharmaceuticals. This seminar will cover the basic principles of near-infrared analysis, as well as workshops on creating calibration curves and measurements using actual equipment. We hope you will join us. 【Seminar Overview】 ■ Date: May 29, 2025 (Thursday) 13:00 - 16:30 (Doors open at 12:30) ■ Venue: NLC Shin-Osaka Building, Basement 1 Conference Room ■ Address: 5-9-5 Nishinakajima, Yodogawa-ku, Osaka City, 532-0011 ■ Capacity: 30 people (Registration will close once capacity is reached) ■ Participation Fee: Free