[End] Innovation Forum 2023 "Simplification of pDNA|mRNA Manufacturing Process by Sartorius"

New standards for integrity testing machines that comply with the latest data integrity and QRM.

The Zaltcheck series is the most widely used in the pharmaceutical industry and has gained the trust of many users as a proven integrity testing device. The Zaltcheck 5 Plus is the latest model in the series, released in 2019. With new technology, we have further enhanced usability, compliance with the latest regulations, and error detection capabilities. It sets a new standard for integrity testing devices that meets the needs of customers seeking higher levels of testing. 【Main Features of the Product】 ■ Specifications that exceed QRM legal requirements - Automatic detection of test setting errors and abnormal test conditions ■ Highest level of data integrity - Customized Linux OS - Data encryption and dual data backup ■ Intuitive and excellent operability - Large touchscreen with a clear viewing angle and intuitive user interface - First in the series to support Japanese display ■ Achievement of Health, Safety, and Environment (HSE) - Explosion-proof specifications (ATEX IECEx & FM certified) that allow safe testing of alcohol-wetted filters *For more details, please contact us or download the PDF materials.

• others

Bioreactor system for cell line development and process optimization.

The Ambr1515 Generation 2 is a high-throughput "automated micro-scale bioreactor system" that reproduces the performance of laboratory-scale bioreactors. The system consists of single-use vessels, an automated workstation, and enhanced convenience software. It is designed to be installed in a standard biosafety cabinet for aseptic operations, allowing for parallel monitoring and control of 24 or 48 micro-bioreactor cultures. As the manufacturing processes for biopharmaceuticals become more complex and the density of cultures increases, scientists around the world are facing an unprecedented challenge in developing "clone, medium, and process" that meet new demands. The Ambr15 Generation 2 system enhances equipment performance that influences the success of cultures, improves flexibility, and incorporates new features that reflect user feedback. It helps address the aforementioned challenges and supports the acceleration of research by scientists.

• others

Introducing options and accessories that can be added to the Ambr 15 Generation 2.

You can find the following information in this catalog: ▪ System specifications ▪ Compatible at-line analyzers ▪ Expandable options ▪ Accessories ▪ Ambr 15 microbioreactor (culture vessel) ▪ Plates and chips

• Other physicochemical equipment
• others

Single-use culture equipment that meets the requirements of the microbial culture process.

【Advantages】 ▪ Specifications designed to accommodate all microbial culture processes ▪ Production of plasmid DNA ▪ Microbial culture bags that have undergone qualification for GMP manufacturing ▪ Improved productivity and user-friendly ▪ Refined process control proven in cell culture

• others

Rapid at-line analysis chromatography solution

【Features】 ▪ High-speed, high-resolution HPLC analysis for pDNA processes ▪ Acceleration of PD and stabilization of manufacturing and quality through at-line monitoring ▪ Ability to obtain a lot of important information in a short time, with low effort and low cost ▪ Unique monolithic column for CIMac pDNA analysis ▪ User guide, dedicated validated methods, SOPs, and standard materials included

• others

Fully automated tangential flow filtration system using a closed-loop single-use system suitable for process development to pilot-scale manufacturing.

**Features** - Single-use TFF specifically designed for 1 to 20L scale, providing cost-effective solutions from process development to pilot. - Ready-to-use and closed system, resulting in low bio-burden risk. **Characteristics in ADC Manufacturing** - Automation of three processes: ADC synthesis, precipitate removal, and TFF within a single system. - Reduction of funding, labor, installation space, and process risks, enabling a seamless transition from process development to small-scale commercial ADC manufacturing. - Flexible process sequence control allows for compatibility with various ADC manufacturing protocols. - Stirring optimized for minimal capacity with temperature control.

• others

Technology for clarification of cell cultures and removal of impurities: Sartoclear Depth Filter

The Zaltclear Depth Filter product family is a cellulose-based filter that contains diatomaceous earth. It is used in the biotechnology and pharmaceutical industries, where high solid removal capabilities are required to meet strict standards. In a dual-layer (DL) format, it can filter cell culture media with a cell density of less than 15×10⁶/mL from the process development stage to the commercial production stage.

• others

Please check the Japanese version catalog for a significant increase in operability and stirring power!

A high-speed, flexible, and intelligent single-use mixer that accommodates all stirring processes in cGMP-compliant bioprocessing. In mixing processes within the bioprocess environment, quality and efficiency are critically important, and the choice of mixing equipment has a dramatic impact on both. A high-speed, flexible single-use mixer enhances manufacturers' competitiveness and improves productivity.

• others

A robust, complete, and scalable solution for frozen storage and frozen transportation.

Based on over 15 years of experience in the design of single-use freezing and thawing solutions, we have established Celsius pre-design solutions (PDS) for all processes requiring frozen storage and frozen transport, at both lab scale and manufacturing scale. Celsius PDS separates the downstream process and is equipped with the necessary functions for the safe transport of active pharmaceutical ingredients to pharmaceutical manufacturing facilities.

• others

Smart condition setting, a genuine end-to-end integrated freeze-thaw system.

A robust, complete, and scalable solution for frozen storage and frozen transport. Sartorius offers lab-scale Celsius solutions for smarter and earlier process decisions in the management of frozen active pharmaceutical ingredients. The Celsius Lab-scale Platform enables the characterization of freezing and thawing within single-use bags of 30 mL to 100 mL, featuring complete scalability up to the commercial-scale Celsius Platform (CFT, FFT, and FFTP).

• Other physicochemical equipment
• others

Freeze-thaw solutions for seamless scalability to commercial production.

Sartorius, with over 15 years of experience in the design of freeze-thaw solutions, offers lab-scale and manufacturing-scale solutions for all steps of processes requiring frozen storage and frozen transport. This enables biopharmaceutical manufacturers to effectively decouple downstream processes and safely transport active pharmaceutical ingredients to drug manufacturing facilities. The Celsius Platform, equipped with options for blast freezers, horizontal freezers, and vertical plate freezers, provides an end-to-end integrated approach that enables monitoring and control to broadly ensure product quality and integrity.

• Other physicochemical equipment
• others

[Exhibition Display] Demonstration of pineapple adhesion dynamics using collaborative robots Dynamic display using collaborative robots and tool changers for gripping Static display of a 5kg dual-sided gripper Comparison of ejector compressed air consumption Various suction pads Foam gripper, etc. We recommend visiting on the first or second day when you can view the exhibits with relative ease. *The third day (Friday) is expected to be very crowded. 【Gripper Sale Event】 We will be selling the following two products at a discounted price at the exhibition booth. Please inquire about the special prices at the venue. ■ 'KENOS Gripper KVGL.400.100, N214.FR6.S2' URL: https://www.youtube.com/watch?v=HsNRwrDtjW0 ■ 'Collaborative Robot Hand KCS.Q110.N301.110.FR6.SX422.V1.X.X' URL: https://www.youtube.com/watch?v=GFKg3blZzdQ These products are ideal not only for actual applications but also for use as test machines. How about taking this opportunity?

[Speaker] Innovation Analyst Andy Kondo [Key Lecture Content] *The latest content will be added as appropriate based on on-site research at CES. The following may change depending on the event status.* CES has now become "the world's largest mobility exhibition," comparable to an auto show. The focus for 2026 will be on the social implementation of autonomous driving, the rise of Software-Defined Vehicles (SDV), the proliferation of AI-equipped vehicles, and the rapid growth of Chinese OEMs, all of which are converging to rewrite the industrial structure. In this lecture, from the perspective of an analyst who has been on-site for over 10 years, we will interpret where the global mobility industry is headed based on the "real scene of CES 2026." Furthermore, we will discuss how these changes will impact and create opportunities in the Japanese market, which is finally beginning to embrace electrification, while aligning with the latest international trends.

[Speaker] Representative of Infonavi Instructor at Business Breakthrough University, Ms. Yoshie Ueno [Lecture Topics] 1. What is a document? - The role of "documents" 2. The success or failure of document creation lies at the entrance - There are procedures for information research - Planning the research 3. Thinking about document creation with a framework - Preventing omissions and eliminating waste - Examples of framework utilization 4. Considering from information sources - There are different types of information - Main information sources for business research 5. How to read and assess documents - Criteria for evaluating information 6. How to create effective documents - Enhancing persuasiveness and trustworthiness 7. Q&A / Business card exchange

Toshiba Electronic Devices & Storage Corporation will exhibit at the "Expo Reborn Challenge Business Expo." The highlight this time is the air-conditioned clothing utilizing the Peltier element, which became a hot topic at the expo! We are currently advancing its development, allowing for precise control of cooling and heating to significantly enhance the comfort of the working environment. Additionally, we will have the popular "Temperature Sensation Game" using the Peltier element that was a hit at the expo! Please experience the technology that garnered attention at the expo at our booth. Furthermore, we will showcase our brushless motor driver, which offers the flexibility to operate three motors from other manufacturers with a single controller, and development is smooth when controlled with a Raspberry Pi! We will also display the screen printing machine "T-Shirt-kun," which was well-received at the Push Activity EXPO, along with trading company products related to T-shirt printing, proposing possibilities for creating original goods. We invite you to experience the latest technology and new business models at our booth.

A free seminar that breaks down the development procedures of system engineers into creating scenarios with WinActor in an easy-to-understand manner! We will introduce hints on the engineer's mindset that can help solve your problems! Even those with no programming experience can become professionals in WinActor. Rest assured. Let us support you in confidently creating your scenarios! <Agenda> - Introduction: The five processes of system development - Requirements Definition: What kind of scenario will you create? Three perspectives - Design: How to create a scenario? - Development: Scenario creation! Things to be careful about are ○○ and ○○! - Testing: After completing the scenario, check ○○! - Release and Maintenance: Before starting to use the scenario, let's do ○○ = For details and registration, click here = ~ Until March 31, 2026 (Tuesday) https://www.nttd-bb.com/event/smn20251202.html?utm_source=ipros&utm_medium=other&utm_campaign=20251205_sales