Fully automated tangential flow filtration system using a closed-loop single-use system suitable for process development to pilot-scale manufacturing.
**Features** - Single-use TFF specifically designed for 1 to 20L scale, providing cost-effective solutions from process development to pilot. - Ready-to-use and closed system, resulting in low bio-burden risk. **Characteristics in ADC Manufacturing** - Automation of three processes: ADC synthesis, precipitate removal, and TFF within a single system. - Reduction of funding, labor, installation space, and process risks, enabling a seamless transition from process development to small-scale commercial ADC manufacturing. - Flexible process sequence control allows for compatibility with various ADC manufacturing protocols. - Stirring optimized for minimal capacity with temperature control.
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basic information
Sartoflow Expert SU is a single-use TFF system that allows for configuration selection to accommodate various applications. In addition to cutting-edge TFF steps, processes such as 0.2 μm filtration and temperature-controlled mixing are incorporated into a single system. The ability to operate multiple processes together is extremely useful in the manufacturing of mRNA, pDNA, and ADC.
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Company information
Sartorius Stedim, established in 2007 through the merger of the German company Sartorius, founded in 1870, and the French company Stedim, is a pioneer in "Single-Use Technology (SUT)." As a company capable of providing comprehensive technical support to the pharmaceutical and biotechnology industries, its cutting-edge technology is highly regarded worldwide in the fields of scientific instruments and biotechnology.