July 4th Process Modeling and Simulation Seminar "From Continuous Production Process of Solid Dosage Forms to Oral Absorption" *The day before the Interfaces event

Visualize the manufacturing process for pharmaceuticals and food! For improving quality and reviewing production costs in active ingredient manufacturing and formulation processes. *Demo tests are currently being conducted.

This is a modeling tool developed in collaboration with a U.S. mega-pharma company. Recently, the pharmaceutical industry has been transitioning from batch to continuous production, and it is being used for process design and control system considerations. It is a model library of gPROMS FormulatedProducts. In continuous production processes, advanced quality management (PAT, QbD, RTRT) and the ability to accommodate small-batch, diverse production become possible, but at the same time, high-precision process modeling technology becomes essential. If you want to "reduce plant construction costs," "increase production volume at existing plants," or "improve product quality (particle size distribution)," please feel free to contact us! You can watch the video on YouTube: https://youtu.be/AJZcgI-r2Ik

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• Analysis Services

Pre-testing in simulations allows for risk avoidance in scaling up. We offer consulting services. Monthly contracts available.

The spray dryer allows for the consideration of product quality variation control and equipment scale-up (enlargement) by simulating factors that influence particle size control, moisture content control, and particle shape during the manufacturing process. In modeling, the particle size distribution is calculated based on the Population Balance equation, and the drying process of the particles is also taken into account. Additionally, representing adhesion to the walls is an important requirement in the simulation. With the integration of Siemens' STAR-CCM+, it is possible to analyze the actual gas flow in detail, which can be used for considerations of scale-up and operational improvements. This is an optional feature of gPROMS FormulatedProducts. *For more details, please download the catalog or contact us.

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• Contract Analysis
• Analysis Services

For increasing production volume, optimizing operations, scale-up design, cost reduction, energy saving, etc.!

<gPROMS FormulatedProducts Crystallization Process Library> It can be used for various considerations and decision-making in production volume enhancement, operational improvement, and process optimization. To build efficient procedures (recipes) in the crystallization process, we will efficiently carry out operations in the following flow and achieve these within a short period (approximately 1 to 2 months). Modeling → Experiment → Model Verification (Parameter Estimation, Validation) → Process Optimization Consideration → Scale-Up Consideration The ability to automatically perform parameter estimation with the tool is a significant factor in reducing the consideration period. Additionally, since it is a kinetic model (expressing mechanisms in mathematical formulas), the number of parameters is kept to a necessary minimum. Furthermore, tools that automatically optimize cooling temperature reduction methods and patterns, the amount and timing of seed crystals, evaporation rates, and heating patterns are powerful, and scale-up may be conducted in conjunction with CFD (Computational Fluid Dynamics) simulations when necessary.

• Contract Analysis

For the pharmaceutical industry and university pharmacy departments: Materials are currently being provided for the simulation of "continuous production" and the optimization of new drug development.

gPROMS Formulated Products is a modeling tool for solid and powder processes. In cases applied to pharmaceutical processes, it enables consistent performance analysis of the entire system, from active pharmaceutical ingredient (API) manufacturing through formulation processes to risk analysis of oral absorption. Our software has already been implemented by major pharmaceutical companies in Europe, the United States, and Japan. We will send you three simulation materials related to API manufacturing, crystallization, formulation, and oral absorption (Technical Information Association, separate print) by mail (free of charge). 1. Optimal design of API manufacturing and formulation processes using modeling tools 2. Optimization of crystallization processes using simulation and modeling tools 3. Correlation between process parameters and quality characteristics using AI We hope this will be useful as part of further efficiency improvements in "continuous production" and new drug development. If you are interested, please contact us by writing "Request for Process Modeling Materials" in the "Inquiry" section.

• simulator
• Analysis Services

Visualize continuous processes! For improving quality and reviewing production costs in active pharmaceutical ingredient manufacturing and formulation processes. *We provide support from demo tests to utilization follow-up.

This is a modeling tool developed in collaboration with a U.S. mega-pharma company. Recently, the pharmaceutical industry has been transitioning from batch production to continuous production, and it is being used for process design and control system considerations. It is a model library of gPROMS FormulatedProducts. In continuous production processes, advanced quality management (PAT, QbD, RTRT) becomes possible, as well as the ability to handle small-batch, multi-product production, but at the same time, high-precision process modeling technology becomes essential. If you have any inquiries such as "I want to reduce plant construction costs," "I want to increase production volume at existing plants," or "I want to improve product quality (particle size distribution)," please feel free to contact us! 【Features】 ■ Capable of steady-state and dynamic (dynamic) simulation ■ Easily handles multiple recycle streams ■ Allows for optimization considerations of plant design and operation methods ■ Can identify and estimate process equipment performance from test data ■ Provides graphical representation of batch plant operating procedures ■ Can be linked with crystallization process analysis libraries ■ Can be linked with oral absorption analysis libraries *For more details about the product, please download the PDF from the link below.

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• Other analyses
• Analysis Services

[Speaker] Jun Ishikawa, Professor at the Graduate School of Business Administration, Rikkyo University, and Vice President of Rikkyo University [Key Lecture Content] This lecture will provide a clear explanation of the most effective leadership in the VUCA era, focusing on shared leadership based on the latest research. Specifically, it will discuss how everyone can exhibit effective leadership to improve workplace and team outcomes, and how anyone can develop effective leadership skills through training. Additionally, it will explain what is necessary to foster shared leadership in workplaces and teams from both individual and organizational perspectives. To continue achieving results in the VUCA era, let’s challenge traditional views of leadership and explore new leadership concepts. [Lecture Items] 1. Characteristics of the VUCA Era 2. What is Shared Leadership? 3. Effects of Shared Leadership 4. Effectiveness of Personal Leadership Theories 5. How to Foster Shared Leadership in Workplaces and Teams 6. Q&A *This seminar will be held via Zoom meeting.*

[Speaker] PwC Advisory LLC Senior Manager Toshiya Nakamura [Key Lecture Content] The expected roles of smart meters (AMI) and DER (Distributed Energy Resources) in power systems are increasing both domestically and internationally. The DISTRIBUTECH conference, one of North America's largest exhibitions and conferences for transmission, distribution, and energy-related technologies, will be held in early February 2026 in San Diego, North America. Numerous power companies and manufacturers introduced the latest trends regarding the next-generation smart meter systems AMI 2.0 and the utilization of DER. In this lecture, I will share the latest trends in the utilization of smart meters and DER in the decentralization of power systems gained through participation in DISTRIBUTECH. [Lecture Items] 1. Overview of DISTRIBUTECH 2. Latest trends in AMI 2.0 3. Latest trends in DER utilization 4. Considerations for the utilization of smart meters and DER 5. Q&A / Business card exchange

[Speaker] Mr. Li Qiangfu, Senior Researcher, Planning and Research Department, Fourin Inc. [Lecture Topics] 1. Tesla Master Plan: Progress of Existing and New Businesses 2. Strategy as a Technology Trendsetter 3. Initiatives in Purchasing and Supply Chain 4. Efforts as an IT Service Platform Provider 5. Competition with Chinese Companies and Strategies to Differentiate 6. Q&A / Business Card Exchange

We will be exhibiting at the "55th ASM OSAKA 2026" held at Intex Osaka. At this exhibition, you can see demonstrations of our layered automatic cutting machine (NC cutting machine) <P-CAM R>, which offers improved cutting accuracy and productivity with excellent cost performance, as well as the automatic fabric spreading machine <P-SPR2L>, which can spread fabric in an optimal state for cutting. We will also introduce our apparel CAD (design CAD) software <APEXFiz PGM>, which achieves excellent efficiency and operability through enhanced integration with cutting machines, from pattern design to size development, and our design software <APEXFiz Design>, which allows for everything from planning and design to color consideration, realistic fabric simulation, and 3D virtual sampling of products. Booth No.: 1 Exhibition Contents: P-CAM R P-SPR2L P-CAM120C SWG091N2 APEXFiz PGM SDS KnitPaint-Online APEXFiz Design Cutting Samples Knit Samples <Contact Information> Cutting Solutions Division, Moriuchi, TEL: 073-474-8239

The goal is to understand the roles and functions of lithium-ion batteries and protection ICs, learn the basics of lithium-ion batteries and protection ICs, and provide fundamental information that can assist in the selection of protection ICs and subsequent circuit design. ● Target Participants - New employees and young designers at companies developing products related to lithium-ion batteries - Those who want to revisit the study of lithium-ion protection ICs - Those who are about to engage in circuit design related to lithium-ion batteries ● Agenda 1. What is a lithium-ion battery? 2. Types of lithium-ion secondary batteries (LIB) 3. Major manufacturers of LIB (Cell Maker) 4. LIB Supply Chain 5. Why is protection for LIB necessary? 6. Methods of LIB protection 7. Basic operation of protection circuits 8. Product lineup of Nisshinbo Micro Devices 9. Chip cross-section (process structure) 10. Rules for product names 11. Trends and considerations for secondary batteries (to be added in 2026) 12. Q&A