Notice of Participation in the "Japan Biomaterials Society" Exhibition from November 6 (Monday) to November 7 (Tuesday), 2023.

There are numerous research examples, including skin models and models of various organs (heart, liver, kidneys, etc.)!

We would like to introduce our bio 3D printer, the "BIO X Series." We offer the "BIO X" and "BIO X6," which allow for flexible use according to research purposes. As an application example, in "cell and molecule encapsulation," cells, drugs, proteins, spheroids, and more can be embedded within hydrogel beads. Additionally, it is possible to print multiple cells and materials using up to six print heads. 【Flexible Use According to Research Purposes】 ■ Utilize multiple print heads ■ Continuously print models ■ Create flexible 3D models ■ Dispense materials like Matrigel *For more details, please refer to the PDF document or feel free to contact us.

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Compatible with a wide range of materials. Ensures high cleanliness with UV-C lamps and HEPA filters. Also focuses on ease of use.

The "BIO X" is a desktop bio 3D printer equipped with an intelligent print head (iPH) that can accommodate a wide range of materials. It features two high-output fans at the top of the device, which pressurize the cavity with clean air filtered through HEPA filters and other means. Additionally, it is equipped with UV-C lamps that maintain a clean printing environment through an automatic cycle. 【Features】 ■ Compatible with temperature-sensitive materials such as collagen and gelatin ■ A wide lineup of high-performance print heads ■ Easy replacement of print heads ■ Suitable for a wide range of applications *For more details, please refer to the materials. Feel free to contact us with any inquiries.

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Highly flexible 3D bioprinting! Featuring a bio 3D printer with cell ink.

Cell culture, which is essential in fields such as regenerative medicine, oncology using stem cells, drug discovery, and toxicity evaluation, is still predominantly conducted in two-dimensional cultures. However, some may wonder if conducting experiments in three dimensions, similar to the cells themselves and the surrounding environment in vivo, would allow for a more faithful study of cell behavior. In this document, we introduce the importance of three-dimensional culture and our company's 3D bioprinting technology, as discussed with our application specialists. We encourage you to read it. [Contents (partial)] - Highly flexible 3D bioprinting - Usable even by beginners, allowing for plenty of trial and error - Extrusion printer BIO X - Light-curing bioprinting LUMEN X+ *For more details, please refer to the PDF document or feel free to contact us.

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Cells are suspended in a gelatin-based biomaterial and shaped using a bioprinter. Subsequently, bone formation differentiation is induced and evaluated during culture.

We are introducing application examples utilizing the BIO X series 3D bioprinter. This product allows for flexible use tailored to research purposes across a variety of applications. There are numerous research cases, including skin models, various organ models (such as heart, liver, kidney, etc.), and cancer disease models. [Contents] - Bioprinting of primary human mesenchymal stem cells and vascular endothelial cells - Multilayer tissue models using multiple cells and materials - Encapsulation of cells and molecules - High-precision automatic dispensing of Matrigel *For more details, please refer to the PDF materials or feel free to contact us.

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Developed a bio-ink composed of human endothelial cells, human pericytes, and animal collagen, and printed the structure.

Current artificial skin graft products promote wound healing, but they ultimately detach because they do not integrate with the patient's skin tissue. The lack of a functional vascular system in artificial grafts poses a significant barrier. We have developed a bioink composed of human endothelial cells, human pericytes, and animal collagen, allowing us to print these structures using the "CELLINK BIO X" and a temperature-controlled print head. This combination of critical elements enables cells to initiate communication and begin forming vascular structures with characteristics similar to biological blood vessels within weeks. Once the vessels are formed, they can exchange nutrients and waste, sustaining the survival of the graft. [Overview] ■ Institution: Rensselaer Polytechnic Institute ■ Challenge: The lack of a functional vascular system in artificial grafts is a significant barrier ■ Solution: Using CELLINK BIO X and a temperature-controlled print head ■ Results - Begin forming vascular structures with characteristics similar to biological blood vessels within weeks - Once vessels are formed, they can exchange nutrients and waste, maintaining the survival of the graft *For more details, please refer to the related links or feel free to contact us.

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Introducing bio-printing technology for 3D heart models designed for personalized medicine and transplantation.

In Dr. Carmine Gentile's laboratory in Sydney, research is being conducted to develop bio-printed heart tissue using patient-specific cells to minimize the risk of transplant rejection. In a 2020 study, mouse cells were bio-printed using alginate-gelatin hydrogel with CELLINK's "BIO X." The bio-printed heart cells were cultured for 7 to 14 days until they developed into pulsating patches of heart tissue. During open-heart surgery on mice from which the cells were derived, the vascularized heart patches were transplanted into the damaged areas of the heart. The transplantation aimed to test the safety of the bio-printed patches and confirm their positive effects on heart function, both of which were validated. [Summary] - Facility: Dr. Carmine Gentile's laboratory in Sydney - Challenge: Development of bio-printed heart tissue - Results: - Safety of the bio-printed patches - Positive effects on heart function *For more details, please refer to the related links or feel free to contact us.*

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Pursuing ease of use! Enables high-resolution printing using living cells.

The "BIONOVA X" is a type of bio 3D printer that cures hydrogels using DLP light crosslinking. It has a high resolution of about 10μm and also supports grayscale printing (changing the illumination according to the pixel intensity in the model image). Developed in the lab of Dr. Shaochen Chen at UCSD, this device accommodates a variety of applications and can be applied to the development of axonal guides for spinal injury treatment. 【Features】 ■ Can print directly onto well plates with up to 24 wells ■ Provides an ideal environment for high-throughput applications ■ Capable of easily modeling tiny structures and complex shapes such as vascular systems ■ Patented continuous printing technology ■ Achieves overwhelming speed without sacrificing print fidelity *For more details, please refer to the related links or feel free to contact us.

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Nitto Kohki will hold the "2025 Attack Fair in Meiko" for two days from July 23 (Wednesday) to July 24 (Thursday), 2025, at the "Kowa Seminar Plaza 2F Training Room NO.12 (inside Kowa Sports Land)." The Attack Fair is an exhibition where you can actually "see, touch, and operate" Nitto Kohki's products. Additionally, there will be wonderful souvenirs for attendees and many fun activities planned. We look forward to welcoming everyone!

We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will showcase a variety of products, including new ones. We sincerely apologize for the inconvenience during your busy schedule, but we would like to invite you to attend this event. 【 Exhibition Name 】 27th INTERPHEX Week Tokyo https://www.interphex.jp/tokyo/ja-jp.html 【 Dates 】 July 9 (Wednesday) - 11 (Friday), 2025 10:00 AM - 5:00 PM 【 Venue 】 Tokyo Big Sight (3-11-1 Ariake, Koto-ku, Tokyo 135-0063)

On February 13 (Friday), we will be exhibiting a corporate panel at the Interphex Conference in Toyama. We sincerely look forward to your visit. Event Name: Interphex Conference Toyama 2026 Date: February 13, 2026 (Friday) Venue: Toyama International Conference Center Panel Content: New Proposals for Tablet Pressing Issues (TL Business: PVD Coating Processing)

We will be exhibiting at the "23rd Japan Yarn Fair" held at the Ichii Shinkin Arena on February 19 (Thursday) and 20 (Friday), 2026. We will showcase a variety of knitted samples, including pullovers and one-pieces made with our computer-controlled flat knitting machines, apparel knit products for sports and outdoor activities, knitted accessories and goods such as socks, gloves, hats, scarves, leggings, and bags, as well as knitted interior products like chairs, cushions, and rugs. Additionally, we will present industrial knitted materials for wearable mobility. We will also introduce our design software, APEXFiz Design, and our web service platform, SHIMA SEIKI Online Services. Booth No.: Sen-1 Exhibition Contents: Knitted Samples APEXFiz Design (Design Software) SDS KnitPaint-Online (Knitting Software) yarnbank (Comprehensive Web Service for Yarn Information) SHIMA Datamall (Digital Content Web Service) <Contact Information> Nishi-Nihon Branch, Kodama, TEL: 0725-31-0511

[Lecturer] Koichi Iwama, Professor, Faculty of Economics and Management, Wako University / Chairman, Resource Economics Committee, Petroleum Technology Association [Key Lecture Content] The latest trends surrounding hydrogen and ammonia, including household fuel cells, fuel cell vehicles, fuel cell trucks, fuel cell buses, hydrogen stations, hydrogen power generation, hydrogen engines, hydrogen-reduced steelmaking, and ammonia ships. The lecture will clearly explain the optimal business strategies for Japanese companies towards a hydrogen and ammonia society by 2030, in the context of the headwinds from the Trump administration and the fierce competition from Western countries and China.