Notice of Participation in the "Japan Biomaterials Society" Exhibition from November 6 (Monday) to November 7 (Tuesday), 2023.

There are numerous research examples, including skin models and models of various organs (heart, liver, kidneys, etc.)!

We would like to introduce our bio 3D printer, the "BIO X Series." We offer the "BIO X" and "BIO X6," which allow for flexible use according to research purposes. As an application example, in "cell and molecule encapsulation," cells, drugs, proteins, spheroids, and more can be embedded within hydrogel beads. Additionally, it is possible to print multiple cells and materials using up to six print heads. 【Flexible Use According to Research Purposes】 ■ Utilize multiple print heads ■ Continuously print models ■ Create flexible 3D models ■ Dispense materials like Matrigel *For more details, please refer to the PDF document or feel free to contact us.

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Compatible with a wide range of materials. Ensures high cleanliness with UV-C lamps and HEPA filters. Also focuses on ease of use.

The "BIO X" is a desktop bio 3D printer equipped with an intelligent print head (iPH) that can accommodate a wide range of materials. It features two high-output fans at the top of the device, which pressurize the cavity with clean air filtered through HEPA filters and other means. Additionally, it is equipped with UV-C lamps that maintain a clean printing environment through an automatic cycle. 【Features】 ■ Compatible with temperature-sensitive materials such as collagen and gelatin ■ A wide lineup of high-performance print heads ■ Easy replacement of print heads ■ Suitable for a wide range of applications *For more details, please refer to the materials. Feel free to contact us with any inquiries.

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Highly flexible 3D bioprinting! Featuring a bio 3D printer with cell ink.

Cell culture, which is essential in fields such as regenerative medicine, oncology using stem cells, drug discovery, and toxicity evaluation, is still predominantly conducted in two-dimensional cultures. However, some may wonder if conducting experiments in three dimensions, similar to the cells themselves and the surrounding environment in vivo, would allow for a more faithful study of cell behavior. In this document, we introduce the importance of three-dimensional culture and our company's 3D bioprinting technology, as discussed with our application specialists. We encourage you to read it. [Contents (partial)] - Highly flexible 3D bioprinting - Usable even by beginners, allowing for plenty of trial and error - Extrusion printer BIO X - Light-curing bioprinting LUMEN X+ *For more details, please refer to the PDF document or feel free to contact us.

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Cells are suspended in a gelatin-based biomaterial and shaped using a bioprinter. Subsequently, bone formation differentiation is induced and evaluated during culture.

We are introducing application examples utilizing the BIO X series 3D bioprinter. This product allows for flexible use tailored to research purposes across a variety of applications. There are numerous research cases, including skin models, various organ models (such as heart, liver, kidney, etc.), and cancer disease models. [Contents] - Bioprinting of primary human mesenchymal stem cells and vascular endothelial cells - Multilayer tissue models using multiple cells and materials - Encapsulation of cells and molecules - High-precision automatic dispensing of Matrigel *For more details, please refer to the PDF materials or feel free to contact us.

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Developed a bio-ink composed of human endothelial cells, human pericytes, and animal collagen, and printed the structure.

Current artificial skin graft products promote wound healing, but they ultimately detach because they do not integrate with the patient's skin tissue. The lack of a functional vascular system in artificial grafts poses a significant barrier. We have developed a bioink composed of human endothelial cells, human pericytes, and animal collagen, allowing us to print these structures using the "CELLINK BIO X" and a temperature-controlled print head. This combination of critical elements enables cells to initiate communication and begin forming vascular structures with characteristics similar to biological blood vessels within weeks. Once the vessels are formed, they can exchange nutrients and waste, sustaining the survival of the graft. [Overview] ■ Institution: Rensselaer Polytechnic Institute ■ Challenge: The lack of a functional vascular system in artificial grafts is a significant barrier ■ Solution: Using CELLINK BIO X and a temperature-controlled print head ■ Results - Begin forming vascular structures with characteristics similar to biological blood vessels within weeks - Once vessels are formed, they can exchange nutrients and waste, maintaining the survival of the graft *For more details, please refer to the related links or feel free to contact us.

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Introducing bio-printing technology for 3D heart models designed for personalized medicine and transplantation.

In Dr. Carmine Gentile's laboratory in Sydney, research is being conducted to develop bio-printed heart tissue using patient-specific cells to minimize the risk of transplant rejection. In a 2020 study, mouse cells were bio-printed using alginate-gelatin hydrogel with CELLINK's "BIO X." The bio-printed heart cells were cultured for 7 to 14 days until they developed into pulsating patches of heart tissue. During open-heart surgery on mice from which the cells were derived, the vascularized heart patches were transplanted into the damaged areas of the heart. The transplantation aimed to test the safety of the bio-printed patches and confirm their positive effects on heart function, both of which were validated. [Summary] - Facility: Dr. Carmine Gentile's laboratory in Sydney - Challenge: Development of bio-printed heart tissue - Results: - Safety of the bio-printed patches - Positive effects on heart function *For more details, please refer to the related links or feel free to contact us.*

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Pursuing ease of use! Enables high-resolution printing using living cells.

The "BIONOVA X" is a type of bio 3D printer that cures hydrogels using DLP light crosslinking. It has a high resolution of about 10μm and also supports grayscale printing (changing the illumination according to the pixel intensity in the model image). Developed in the lab of Dr. Shaochen Chen at UCSD, this device accommodates a variety of applications and can be applied to the development of axonal guides for spinal injury treatment. 【Features】 ■ Can print directly onto well plates with up to 24 wells ■ Provides an ideal environment for high-throughput applications ■ Capable of easily modeling tiny structures and complex shapes such as vascular systems ■ Patented continuous printing technology ■ Achieves overwhelming speed without sacrificing print fidelity *For more details, please refer to the related links or feel free to contact us.

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This course is designed to meet the requests of many customers and expands and enriches the content of the previously popular course "Organic Structure Analysis" by including applied topics such as 2D-NMR analysis and chemical decomposition analysis. It is an ideal course for those who have taken the beginner course and want to deepen their understanding of organic structure analysis to aid in research and development.

We would like to inform you about the upcoming semiconductor fundamentals course hosted by Nisshinbo Micro Devices, which has received positive feedback and participation from many attendees each time. This time, we will be presenting "Introduction to Power IC Linear Regulators." The difficulty level is beginner, so we encourage everyone, from those who want to start learning about analog ICs to those facing challenges, to participate actively. With recorded lectures and live chat Q&A with our technical engineers, even busy engineers can learn efficiently. ● Target Participants - New employees and young designers - Those who want to refresh their knowledge of analog ICs - Those preparing for circuit design ● Agenda 1. What is a Power IC? 2. Linear Regulators - Shunt Regulators - Series Regulators 3. Key Characteristics 4. Main Functions 5. External Components 6. Thermal Characteristics We look forward to your participation.

In the world, there are more information systems than there are companies, but the number of systems that truly "help with a company's business operations" in a meaningful way is limited. To address this challenge, our company has developed and evolved our unique supply chain solutions, the "Φ-Conductor Series" and "Φ-Pilot Series." Since our establishment, we have upheld the philosophy of "together with our customers, for our customers," and, unlike many IT vendors, we have consistently focused on the effectiveness of our implementations, steadily building our track record. Therefore, on the occasion of our 25th anniversary, we have decided to hold an event where customers who have implemented our solutions will share their experiences regarding the effectiveness of the implementation and any challenges they faced. The companies presenting will include a diverse range of six user companies, primarily from the food industry. Additionally, at the concurrently held exhibition, we will showcase our original lineup, the "Φ-Pilot Series" and "Φ-Conductor Series," along with add-on features and optional products related to φ-Pilot that our partner companies are working on. We warmly invite you to attend this event.

[Speaker] Ministry of Economy, Trade and Industry, Manufacturing Industries Bureau, Automotive Division Deputy Director Toshiki Okabayashi [Key Lecture Content] Japan's basic policy is the "Multi-Passthway Strategy," which pursues various options such as EVs, PHEVs, hydrogen, and synthetic fuels to achieve carbon neutrality in the automotive sector. This lecture will introduce the direction of automotive policy while considering global electrification trends, policy trends in major countries, and changes in domestic and international market structures. [Lecture Items] 1. Current Situation Surrounding the Automotive Industry - Policy trends in major countries - Market trends in major countries 2. GX-related Initiatives - Electrification - Utilization of hydrogen in the mobility sector - Expansion of synthetic fuel introduction 3. Q&A / Business Card Exchange

Attention those using open columns for purification and tired of checking TLC after separation! "We're still using open columns? It's not just about automation; let's explore the benefits of flash chromatography." We will be hosting a webinar. - How much time and solvent can be saved by introducing flash chromatography? - What impact does it have on separation? - Tricks that cannot be applied to open columns. Let's consider the advantages of flash chromatography that go beyond just making things easier! 【Target Audience】 - Those using open columns - Those interested in flash chromatography - Those considering the introduction of flash chromatography - Those who want to know the benefits of flash chromatography We look forward to your participation. *Please note that participation from competing companies is not allowed.