Notice of Participation in the "Japan Biomaterials Society" Exhibition from November 6 (Monday) to November 7 (Tuesday), 2023.

There are numerous research examples, including skin models and models of various organs (heart, liver, kidneys, etc.)!

We would like to introduce our bio 3D printer, the "BIO X Series." We offer the "BIO X" and "BIO X6," which allow for flexible use according to research purposes. As an application example, in "cell and molecule encapsulation," cells, drugs, proteins, spheroids, and more can be embedded within hydrogel beads. Additionally, it is possible to print multiple cells and materials using up to six print heads. 【Flexible Use According to Research Purposes】 ■ Utilize multiple print heads ■ Continuously print models ■ Create flexible 3D models ■ Dispense materials like Matrigel *For more details, please refer to the PDF document or feel free to contact us.

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Compatible with a wide range of materials. Ensures high cleanliness with UV-C lamps and HEPA filters. Also focuses on ease of use.

The "BIO X" is a desktop bio 3D printer equipped with an intelligent print head (iPH) that can accommodate a wide range of materials. It features two high-output fans at the top of the device, which pressurize the cavity with clean air filtered through HEPA filters and other means. Additionally, it is equipped with UV-C lamps that maintain a clean printing environment through an automatic cycle. 【Features】 ■ Compatible with temperature-sensitive materials such as collagen and gelatin ■ A wide lineup of high-performance print heads ■ Easy replacement of print heads ■ Suitable for a wide range of applications *For more details, please refer to the materials. Feel free to contact us with any inquiries.

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Highly flexible 3D bioprinting! Featuring a bio 3D printer with cell ink.

Cell culture, which is essential in fields such as regenerative medicine, oncology using stem cells, drug discovery, and toxicity evaluation, is still predominantly conducted in two-dimensional cultures. However, some may wonder if conducting experiments in three dimensions, similar to the cells themselves and the surrounding environment in vivo, would allow for a more faithful study of cell behavior. In this document, we introduce the importance of three-dimensional culture and our company's 3D bioprinting technology, as discussed with our application specialists. We encourage you to read it. [Contents (partial)] - Highly flexible 3D bioprinting - Usable even by beginners, allowing for plenty of trial and error - Extrusion printer BIO X - Light-curing bioprinting LUMEN X+ *For more details, please refer to the PDF document or feel free to contact us.

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Cells are suspended in a gelatin-based biomaterial and shaped using a bioprinter. Subsequently, bone formation differentiation is induced and evaluated during culture.

We are introducing application examples utilizing the BIO X series 3D bioprinter. This product allows for flexible use tailored to research purposes across a variety of applications. There are numerous research cases, including skin models, various organ models (such as heart, liver, kidney, etc.), and cancer disease models. [Contents] - Bioprinting of primary human mesenchymal stem cells and vascular endothelial cells - Multilayer tissue models using multiple cells and materials - Encapsulation of cells and molecules - High-precision automatic dispensing of Matrigel *For more details, please refer to the PDF materials or feel free to contact us.

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Developed a bio-ink composed of human endothelial cells, human pericytes, and animal collagen, and printed the structure.

Current artificial skin graft products promote wound healing, but they ultimately detach because they do not integrate with the patient's skin tissue. The lack of a functional vascular system in artificial grafts poses a significant barrier. We have developed a bioink composed of human endothelial cells, human pericytes, and animal collagen, allowing us to print these structures using the "CELLINK BIO X" and a temperature-controlled print head. This combination of critical elements enables cells to initiate communication and begin forming vascular structures with characteristics similar to biological blood vessels within weeks. Once the vessels are formed, they can exchange nutrients and waste, sustaining the survival of the graft. [Overview] ■ Institution: Rensselaer Polytechnic Institute ■ Challenge: The lack of a functional vascular system in artificial grafts is a significant barrier ■ Solution: Using CELLINK BIO X and a temperature-controlled print head ■ Results - Begin forming vascular structures with characteristics similar to biological blood vessels within weeks - Once vessels are formed, they can exchange nutrients and waste, maintaining the survival of the graft *For more details, please refer to the related links or feel free to contact us.

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Introducing bio-printing technology for 3D heart models designed for personalized medicine and transplantation.

In Dr. Carmine Gentile's laboratory in Sydney, research is being conducted to develop bio-printed heart tissue using patient-specific cells to minimize the risk of transplant rejection. In a 2020 study, mouse cells were bio-printed using alginate-gelatin hydrogel with CELLINK's "BIO X." The bio-printed heart cells were cultured for 7 to 14 days until they developed into pulsating patches of heart tissue. During open-heart surgery on mice from which the cells were derived, the vascularized heart patches were transplanted into the damaged areas of the heart. The transplantation aimed to test the safety of the bio-printed patches and confirm their positive effects on heart function, both of which were validated. [Summary] - Facility: Dr. Carmine Gentile's laboratory in Sydney - Challenge: Development of bio-printed heart tissue - Results: - Safety of the bio-printed patches - Positive effects on heart function *For more details, please refer to the related links or feel free to contact us.*

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Pursuing ease of use! Enables high-resolution printing using living cells.

The "BIONOVA X" is a type of bio 3D printer that cures hydrogels using DLP light crosslinking. It has a high resolution of about 10μm and also supports grayscale printing (changing the illumination according to the pixel intensity in the model image). Developed in the lab of Dr. Shaochen Chen at UCSD, this device accommodates a variety of applications and can be applied to the development of axonal guides for spinal injury treatment. 【Features】 ■ Can print directly onto well plates with up to 24 wells ■ Provides an ideal environment for high-throughput applications ■ Capable of easily modeling tiny structures and complex shapes such as vascular systems ■ Patented continuous printing technology ■ Achieves overwhelming speed without sacrificing print fidelity *For more details, please refer to the related links or feel free to contact us.

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[Speaker] Representative Director of KKR Consulting Co., Ltd. Director of Yamada Junya Tax Accountant Office, Tax Accountant Junya Yamada Tax Accountant Mika Ikeda [Lecture Items] ● Explanation of recent renewable energy installation methods, subsidy systems, and tax incentives ● Regarding subsidy systems, explanation of local government subsidies mainly in the Kanto region 【1】Latest renewable energy schemes 【2】Explanation of renewable energy-related subsidies 1. National subsidies 2. Local government subsidies mainly in the Kanto region Tokyo, Kanagawa, Chiba, Saitama, Tochigi, Ibaraki, Gunma, etc. 【3】Explanation of tax systems related to renewable energy generation equipment and storage batteries 1. Immediate depreciation under the Small and Medium-sized Enterprise Management Enhancement Tax System 2. Carbon Neutral Tax System (applicable to large enterprises) 3. Reduction system under the Advanced Equipment Introduction Plan 4. Newly established in FY2026: Productivity Improvement Equipment Investment Promotion Tax System 【4】Q&A / Business card exchange

[Lecturer] Shinsuke Tsutsui, Senior Partner, A.T. Kearney, Inc. Energy Practice [Key Lecture Content] Japan's electricity and energy market is facing significant changes, but the impact of these changes is not necessarily definitive and continues to increase future uncertainties. Against the backdrop of the recent rapid expansion of generative AI and data centers, the previously assumed scenarios for electricity demand suppression are being significantly reassessed, though opinions on this are not uniform. Additionally, on the supply side, the business environment is becoming increasingly challenging due to rising costs and increased risks associated with renewable energy, raising doubts about the assumption of continued expansion, including offshore wind power. The energy basic plan, approved by the Cabinet in February 2025, is not functioning adequately as a foundation for management and business strategies in light of this background. Furthermore, with the introduction of new markets and systems such as real-time markets, supply capacity obligations, medium- to long-term markets, and GX-ETS on the horizon, the ability to respond to regulations has become a key factor in the competitiveness of electricity and energy businesses. In this lecture, we will consider the changes in demand and supply structures, the impact of new markets/systems, and the influence of political and international situations, exploring the key points that companies should focus on in their strategic considerations post-2025 from multiple perspectives.

We are pleased to announce that our company will be exhibiting at the "35th UOS Kansai IT POWER UP Fair 2025," which will be held on Wednesday, October 29, 2025. ▼ Event Overview This exhibition will showcase the latest IT tools from the Kansai region, featuring a total of 27 solutions. We will be presenting "Smartsheet." Date: Wednesday, October 29, 2025, from 11:00 AM to 5:30 PM (Registration starts at 10:45 AM) Location: Osaka Industry Creation Center, 3rd and 4th Floors, 1-4-5 Honmachi, Chuo Ward, Osaka City, Osaka Prefecture Organizer: UOS Group Kansai Branch Participation Method: Pre-registration (free) To register, click here Official website: https://fair.uos.gr.jp/form/kansai2025/ ✔ Those interested in IT ✔ Those facing challenges in project management ✔ Those interested in Professor Fujii's lecture, etc. If you have any interest at all, we would be delighted to see you there! We look forward to welcoming you!

The popular training conducted by ISO certification bodies, which has been held 500 times nationwide over approximately 20 years, has now become an online seminar. This online training can be taken safely from your workplace or home. With no burden of traveling to a venue, the efficient online seminar is now the preferred choice! While many training courses typically last two days, this course has carefully selected key points and is designed to be mastered efficiently in one day. We have received numerous positive comments about having a fulfilling day. Unlike many training sessions that consist of just listening to lectures, our program incorporates engaging elements such as practical group exercises and targeted training, along with explanations based on abundant audit examples and easy-to-understand texts that are also helpful for review. This has led to its adoption in regular training sessions by major manufacturers and global companies. [Feedback from participants] - The specific examples explained were easy to understand. - The text clearly summarized the important points of the standards. - The lecture content was not too formal, which was nice. - The explanations were thorough, allowing us to learn the key points even in a short time. - I enjoyed the group workshops even in the online seminar.

The popular training conducted by ISO certification bodies, which has been held 500 times nationwide over the past 20 years, has now become an online seminar. This online training can be taken safely from your workplace or home. With no burden of traveling to a venue, the efficient online seminar is now the preferred choice! While many training courses typically last two days, this course has carefully selected key points to be efficiently mastered in one day. We have received numerous positive comments about having a fulfilling day. Unlike many training sessions that involve just listening to lectures, our program incorporates engaging elements such as pointed training and practical group exercises, along with clear explanations based on abundant case studies, and easy-to-understand texts that are helpful for review. This has led to its adoption in regular training sessions by major manufacturers and global companies. [Feedback from participants] - The explanation of specific examples was easy to understand. - The text summarized the important points of the standards clearly. - The lecture content was not too formal, which was good. - The explanations were thorough, allowing us to learn the key points even in a short time. - I enjoyed the group workshops even in the online seminar.