Derivatization for GC/MS analysis

Proposals tailored to the purpose of analysis and the target object! GC/MS analysis of derivatized samples.

This document introduces a pretreatment method to enable the analysis of substances that are difficult to analyze using GC/MS. The pretreatment that converts difficult-to-analyze substances into analyzable substances is called "derivatization." Methods such as esterification, acylation, and silylation are used selectively according to the type and characteristics of the difficult-to-analyze substances. GC/MS measurements were conducted on citric acid solutions and citric acid solutions after esterification. It was found that citric acid, being a carboxylic acid, could not be effectively detected without derivatization, but after esterification, trimethyl citrate was detected, confirming the presence of citric acid. By performing appropriate derivatization, more accurate analysis becomes possible. [Analyzable Substances] ■ High volatility ■ High thermal stability ■ Low polarity *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

Introducing a new device! We present an analytical method aimed at the qualitative and quantitative analysis of components contained in samples.

We have introduced the "GC-MS Gas Chromatograph Mass Spectrometer" manufactured by Shimadzu Corporation. This is one of the analytical methods aimed at qualitative and quantitative analysis of components contained in samples, used for the qualitative and quantitative analysis of volatile organic compounds such as parts, materials, residual solvents, and additives. It is necessary for the measurement target to be gasified (with a boiling point below 300°C), but it is suitable for component analysis of mixtures due to its higher sensitivity compared to IR and RAMAN, as well as the ability to separate components in the GC section. 【Overview of GC-MS Equipment】 ■ GC-MS Main Unit: GC-2030, GCMS-QP2020 NX ■ Headspace Sampler: HS-20 ■ Pyrolysis Analyzer: Multi-Shot Pyrolyzer Py-3030 ■ Specifications ・Detection Limit: Several ppm (varies depending on the measurement target) ・Headspace: 40–300°C, Sample Size 13mm x 40mm or smaller ・Pyrolysis Analyzer: 50–1050°C (EGA measurement compatible), Sample Size up to 4mm *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices
• Contract Analysis

What is the reason for this discoloration on the surface? Why are there cracks in such places? These issues will be resolved from the perspectives of electrons, atoms, molecules, and chemical reaction mechanisms!

Many defects occur during the manufacturing process of products and during their use. Among these, there are challenges related to material properties, and for those who are wondering, "It’s probably due to the material, but what should I do about it?", we propose solutions from the perspectives of electronics, atoms, molecules, and chemical reaction mechanisms. ■Examples of Challenges - What is causing this discoloration? - Why did it crack so quickly? - Why does it break immediately when subjected to a tensile test? *For more details, please refer to the PDF document or feel free to contact us.

• Processing Contract
• Other environmental analysis equipment
• others

By adding a special reagent to the sample and heating it, it becomes possible to detect substances that are usually difficult to detect!

In a typical thermal decomposition GCMS, samples are heated to detect volatile components; however, analyzing components that do not volatilize upon heating or those with low detection sensitivity is challenging. Therefore, by adding a special reagent to the sample and heating it, it becomes possible to detect substances that are usually difficult to identify. For example, in the analysis of polymers, thermal decomposition of the polymer results in the detection of a large number of decomposition products, and in some cases, peaks may overlap with other additives, making analysis difficult. However, by performing reactive thermal decomposition GCMS, it is possible to detect the methyl esters of monomers and to separate and analyze them from the additives. Thus, even when the target analytes are difficult to detect using conventional analysis, reactive thermal decomposition GCMS allows for sensitive detection by selecting appropriate reagents for the analytes. [Examples] - Analysis of phthalate esters (DIDP) - Analysis of polymers (polyethylene terephthalate) - Analysis of copper corrosion inhibitors (BTA) *For more details, please refer to the PDF document or feel free to contact us.

• Contract Analysis
• Analysis Services

For material evaluation and defect analysis! We will discuss the applied load and degradation mechanisms based on the differences in decomposition products.

Polycarbonate is a material that excels in impact resistance, weather resistance, and transparency, making it widely used in everything from industrial materials to everyday products. However, even polymers with excellent properties can undergo chemical changes, commonly referred to as degradation, due to the usage environment and the passage of time. This document presents examples of degradation analysis of polycarbonate materials subjected to UV irradiation and constant temperature and humidity testing. [Contents] ■ Thermal decomposition GC-MS analysis of polycarbonate *For more details, please refer to the PDF document or feel free to contact us.*

• Contract Analysis

Introducing the sample introduction device and the types of analytical samples and analysis content that each device specializes in!

GC-MS analysis is a method commonly used for the analysis of organic components and organic structure analysis. With auxiliary devices, it is capable of a wide range of analyses, from low molecular substances like solvents to high molecular substances like plastics. In this document, we will introduce the sample introduction devices owned by Aites, as well as the types of analysis samples and analysis content that each device specializes in. We invite you to read it. 【Contents】 ■ Overview ■ Conditions ■ Samples ■ Data Obtained ■ Analysis Examples *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

I will introduce examples of comparing the components of color developers contained in thermal paper using solvent extraction!

As a pre-treatment for GC-MS analysis, solvent extraction can sometimes allow for highly sensitive analysis of target substances. This document introduces examples of component comparison of dirt wiped with a cloth and component comparison of color developers contained in thermal paper using solvent extraction. In addition to solvent extraction, we can propose suitable methods from various pre-treatment techniques tailored to your samples and analysis targets, so please feel free to contact us. [Contents] ■ Comparative analysis of dirt components and surrounding materials ■ Component comparison of color developers contained in thermal paper *For more details, please refer to the PDF document or feel free to contact us.

• Contract Analysis
• Contract measurement
• Other contract services

Fukuda Co., Ltd. has been pursuing leak detection for 60 years and is committed to advancing the future of leak testing. 【 Supporting Various Leak Tests: Air Leak Test / Gas Leak Test (Hydrogen Gas, Helium Gas) 】 We develop, manufacture, and sell leak testing equipment to inspect airtightness and sealing properties. We will propose the appropriate testers and devices for each inspection target. 【 Target Industries and Examples of Inspection Targets 】 - Automotive Industry: Engines, FC components, valves and piping, various parts - Electronic Components Industry: Smartphones, keyless switches, various small sensors - Pharmaceuticals / Food / Cosmetics Industry: Bottle containers, syringes, vials, eye drop containers, pillow packaging, PTP packaging We will propose the most suitable leak testers for each industry. 【 ISO Certification 】JIS Q 9001:2015 (ISO 9001:2015)

We have launched a "Display Item Search Page" that allows you to search for unit houses currently on display at exhibition halls nationwide, which was made available on January 6, 2026. There are over 800 items listed on the website. You can filter by area, price range, size, purpose, product type, color, and more. You can also check exterior and interior photos, prices, facilities, and drawings/specifications online. If you're interested in a display item, you can directly inquire, make a reservation to visit, or consult via LINE. This is a convenient service that allows you to efficiently progress from comparison to detailed consideration. Please take a look!

A co-authored paper by Shin Otsuki from the Data Science Department and another author has been published in Oxford Open Materials Science. 【Paper Summary】 Title: The Exploration of Enhanced Methods in Data Science and Applications in Materials Science Authors: Raymond Wu, Shin Otsuki

"With high-precision dimming settings of 256/1000 gradations, you can achieve your desired results." The new 1-channel dedicated model LLBLM-A maximizes the performance of high-brightness LEDs. It offers high light stability through constant current control and flexibly accommodates a wide range of inspection and lighting applications with three types of interfaces: parallel, RS232C, and LAN. In addition to intuitive operation via the front panel, it supports high-precision dimming with 256/1000 gradations (256 gradations in parallel mode). The available emission colors are G (green) and B (blue). This new model balances stable light output with ease of use. For more details, please feel free to contact us.

Last month, we held a winter safety conference organized by our company. We have compiled the details and atmosphere of the day, as well as information on winter labor accidents, into a PDF. We would appreciate it if you could take a moment to read it.