[End] Speaker at the Cell Culture Medium Symposium hosted by Shonan I-Park.

Supporting the development of advanced therapies at every stage, from research and development to application in humans.

Features and Benefits ■ Hydrophobic, forms a monolayer on the water surface, reducing surface adsorption ■ Prevents aggregation and minimizes instability by dispersing uniformly in solution ■ Scavenges free radicals and protects against oxidative stress ■ Functions as a pH buffer and nutrient source, supporting an optimal microenvironment for sustained cell survival ■ Supports cell viability during and after freeze preservation ■ A completely non-human and non-animal derived product, reducing logistical challenges

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Maximization of cell quality characteristics, assurance of reproducible results, reduction of development time.

You can check the following Sartorius culture solutions from this catalog: ■ Stem cell culture media, supplements, and reagents ■ Immune cell culture media ■ Recombinant human albumin and biopreservation ■ Other media and reagents ■ Growth factors and cytokines ■ HEK293 media portfolio ■ Services

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For protein production using CHO cell lines.

■ A wide range of products to accelerate media development ■ Sartorius' global manufacturing network that ensures supply ■ 100% known chemical composition, animal component-free, serum-free, and free of hydrolysates with high reproducibility ■ In addition to ready-to-use catalog products, customizable and highly flexible ■ Highly filterable and soluble media and feeds

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Introducing a medium system for protein production using the CHO system!

The starter kit for the culture system "4Cell XtraCHO" includes all the necessary culture components for cell acclimatization and fed-batch culture at a 3L capacity. When progressing to larger-scale cultures, all individual culture components are available in various forms, both liquid and powder. Using production media and feed media offers benefits such as "eliminating process variability and contamination risks." 【Customer Benefits】 ■ Production Efficiency: Ideal efficiency from bench scale to manufacturing scale ■ Compliance with Regulatory Guidelines: Eliminates process variability and contamination risks ■ Reduces Process Complexity: Facilitates purification *For more details, please refer to the PDF materials or feel free to contact us.

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Next-generation chemical components known to support Vero cell proliferation and virus production.

【Features】 ■ Effective for production: Achieves high cell proliferation and virus production in media with known chemical components ■ Efficient operation: Simplifies filtration and purification in downstream processes, improving virus productivity ■ Safety and regulatory compliance: Reduces variability between processes and minimizes contamination risks

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Excellent results and flexibility with xenofree serum-free medium for lymphocyte culture!

Cell-based immunotherapy is at the forefront of cancer treatment. The most common type of cell-based immunotherapy to date is T-cell therapy (with CAR-T and TIL being the mainstream). The cells used in immunotherapy are generally cultured in a medium supplemented with human serum. The use of serum introduces variability in the process due to individual differences among donors, leading to inconsistencies in cell growth and characteristics. By removing this serum and simplifying the process, regulatory risks are reduced, and the associated logistical burdens are alleviated. Nutri-T eliminates the need for serum by replacing its essential components with specific proteins, lipids, and other small molecules. <Product Overview> ■ Xeno-free ■ Serum-free, no serum supplementation required ■ Compliant with ISO13408 ■ For research use only ■ Developed using cells from actual cancer patients ■ Excellent results with PBMC, TIL, and CAR-T ■ Outstanding results at low initial seeding density

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Xeno-free serum-free medium for hES cells and hiPS cells

NutriStem hPSC XF will be registered with the U.S. FDA Drug Master File (DMF)! NutriStem hPSC XF medium is a xeno-free (XF) medium optimized for the culture of human iPS/ES cells. It contains no animal-derived components and is composed entirely of human-derived proteins. NutriStem hPSC XF Medium has the capability to culture human pluripotent cells without the need for high concentrations of bFGF or other stimulatory growth factors or cytokines, enabling long-term culture while maintaining undifferentiated potential under both feeder-free (Matrigel coated) and on-feeder (MEF, HFF) conditions.

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Redefining the excellence of stem cells and advancing clinical applications: a complete xenofree serum-free system for the proliferation and expansion of hMSCs.

MSC NutriStem XF medium is a xeno-free medium for human mesenchymal stem cells (MSC) derived from various tissues such as bone marrow, fat, and Wharton's jelly. It supports the long-term culture of human MSC while maintaining the fibroblast-like morphology, self-renewal ability, and multipotency observed in normal MSC. MSC Attachment Solution - Xeno-free, purified human fibronectin/fibrinogen - Optimized for serum-free culture - For the proliferation and differentiation of hMSC MSC Dissociation Solution - Ready-to-use, known chemical composition - Recombinant trypsin solution NutriFreez D10 Cryopreservation Solution - Known chemical composition, animal-derived component-free, protein-free - Excellent cell adhesion and viability

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Completely serum-free xenofree medium enables advanced adipogenesis, osteogenesis, and chondrogenesis from hMSCs.

MSCgo Xeno-Free Chondrogenic Differentiation Medium is an innovative xeno-free (free of animal-derived components) and serum-free medium designed to directly induce the differentiation of human mesenchymal stem cells (hMSC) from various sources into chondrocytes. A complete medium is prepared from a basic medium and a supplement mix that includes all the growth factors and supplements necessary for differentiation. Additionally, hMSC isolated and expanded with MSC NutriStemXF can be efficiently induced to differentiate into various cell types (fat, bone, cartilage).

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A cost-effective and efficient standardized supplement designed to adhere human mesenchymal stem cells under serum-free and xeno-free culture conditions.

NutriCoat Attachment Solution is a cell adhesion substrate designed for human mesenchymal stem cells (hMSC) based on human fibrinogen, suitable for serum-free and xeno-free culture. It is optimized for human MSC derived from various tissues cultured in MSC NutriStem XF Medium. Additionally, it supports long-term culture of hMSC and the results of colony-forming unit-fibroblast (CFU-F) assays under serum-free and xeno-free culture conditions. This product is a ready-to-use solution that can be stored at room temperature, making it ideal for experiments in cell therapy research.

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Serum-free, animal-derived component-free, protein-free short-term refrigerated (2-8 °C) cell preservation solution.

The cells stored in this solution demonstrate high recovery rates, normal cell characteristics, and excellent performance due to components that provide pH buffer, osmotic support, energy substrates, and ion concentration. ■ Ready-to-use ■ Known chemical composition, free from animal-derived components, serum-free, and protein-free ■ Provides maximum safety during low-temperature storage (2 - 8°C) ■ Ensures high survival and recovery rates after low-temperature storage ■ Ensures the safety of cells during transport ■ Suppresses necrosis and apoptosis after storage ■ Ideal for a wide range of applications ■ DMF preparation in progress ■ Surpasses competitors in the market

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An all-in-one solution designed for freezing and thawing cells, with a known chemical composition, particularly for cell therapy and clinical applications.

NutriFreez D5 Salt Based Cryopreservation Solution provides an environment that can protect cells even at ultra-low temperatures (-196°C), ensuring high survival rates, recovery rates, and performance for very delicate cells. It is manufactured under current GMP conditions and demonstrates industry-leading performance. This product is optimally formulated, containing 5% DMSO, and does not include antibiotics, antifungals, hormones, growth factors, serum, or proteins.

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Powerful cryopreservation medium optimized for various cells and tissues.

NutriFreez D10 freezing preservation medium is a ready-to-use cell freezing solution that is optimized for multiple cell lines, free of animal-derived components, serum-free, and protein-free. When culturing cells in a serum-free environment, it is important to maintain serum-free conditions during cell freezing and preservation. This product has been shown to have high efficiency in cell viability, proliferation, adhesion (in relevant cell lines), and physiological activity/expression even after freezing and thawing. It has demonstrated superior results compared to serum-containing freezing media and other serum-free products, making it an ideal product for both serum-containing and serum-free applications.

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High-quality raw materials for gene cell therapy manufacturing.

■ A smooth transition from the early development stage to the clinical stage with consistent quality and performance ■ Optimal cell proliferation and differentiation ensured by excellent batch-to-batch consistency ■ Regulatory support related to GMP products manufactured in compliance with applicable GMP guidelines

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Next, making cell research and manufacturing easier.

When using cells for large-scale high-quality production, the Sartorius SoloHill microcarriers offer many advantages: ■ Proven track record: Used for over 30 years in the pharmaceutical and healthcare industries for animals and humans. ■ Streamlined solution: Ready to use immediately after sterilization, no prior hydrophilization is required. ■ Ready for immediate use: Sterilized products have a Sterility Assurance Level (SAL) of 10-6, eliminating the need for sterility validation and shortening the manufacturing process.

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We are pleased to announce that JP Generators Co., Ltd. will be exhibiting at the 47th Joint Disaster Prevention Drill of the Nine Prefectures and Cities, which will be held on September 1, 2026 (Tuesday) at the Kanagawa venue, titled "Big Rescue Kanagawa." About Big Rescue Kanagawa: Big Rescue Kanagawa is a practical comprehensive disaster prevention drill focused on medical rescue activities, conducted in collaboration with medical institutions and disaster prevention organizations by Kanagawa Prefecture and Atsugi City at the Kanagawa venue of the Joint Disaster Prevention Drill of the Nine Prefectures and Cities. In addition to rescue training, we have prepared many enjoyable areas where you can learn about disaster prevention, including exhibition and experience corners. Our company will also be exhibiting at this comprehensive disaster prevention drill. ▼ The exhibited product will be the "Vehicle-mounted Generator | G-STREAM." We sincerely look forward to your visit.

[Instructor] Paulstar Communications Inc. Representative Director Koji Kita [Key Lecture Content] Have you ever felt that, despite entrusting work to Generation Z and young employees, they "don't seem to get started," "don't lead to the expected results," or "it's ultimately faster to do it myself"? Behind these situations are various factors, including the recognition gap between supervisors and young employees regarding "entrusting and being entrusted," how to communicate the purpose of the work, the approach, and the scope of discretion, as well as how to follow up after delegating tasks. In this seminar, we will practically explain "how to delegate work" to elicit proactive behavior, taking into account the perspectives and behavioral characteristics of Generation Z and young employees. We will share specific management techniques to help supervisors break free from the burden of work, encourage the autonomy and growth of young employees, and steadily lead to results.

[Speaker] Yoichiro Okuyama, Senior Researcher, Research Department, Hamagin Research Institute, Inc. [Key Lecture Content] In China, the operation of autonomous taxis began in 2021, and now fully unmanned robo-taxis are running in cities like Beijing and Shenzhen. Experiencing a ride reveals the evolution of technology through natural acceleration, smooth steering, and seamless deceleration. Currently, there are several thousand vehicles in operation, but projections suggest that by 2030, this number could exceed one million, accounting for 70% of the global total. What are the underlying factors driving the social implementation of robo-taxis in China? By incorporating local test ride experiences, we will analyze the revenue situation of robo-taxi operating companies and the outlook for market expansion based on data, exploring their future potential. [Lecture Items] 1. Personal experiences of test riding robo-taxis in China 2. Trends in the market size of robo-taxis in China and globally 3. Background of the advancing social implementation of robo-taxis in China 4. Public acceptance and actual usage 5. Performance and challenges of major robo-taxi companies 6. Will robo-taxis become widespread in Japan as well? 7. Q&A / Business card exchange

Daitō Shikō Co., Ltd. will exhibit at the "102nd Tokyo International Gift Show Autumn 2026," which will be held at Tokyo Big Sight from September 2 (Wednesday). At the exhibition venue, we plan to showcase new products including the A7 binder, popular foil-stamped goods, stationery, clear files, and more. If you are looking for SP tools, promotional items, or novelties, please be sure to visit our booth.

JIMTOF2026 JAPAN INTERNATIONAL MACHINE TOOL FAIR (33rd Japan International Machine Tool Exhibition) October 26 (Monday) to October 31 (Saturday), 2026, for six days Venue: Tokyo Big Sight (International Exhibition Center) Opening Hours: [West and South Exhibition Halls] 10:00 AM to 5:00 PM (until 4:00 PM on the last day) Booth Number: W4010-1 in the West Exhibition Hall Exhibitor Name: VARNALCO (our original brand name for automatic lathe tool holders) Our Exhibited Items: Tool holders for Swiss-type automatic lathes (rotating tools) *Spindle extension rods (for Nomura DS automatic lathes, can be attached to some models with guide bushes, can be modified to have equivalent functions to guide bushless models). More details will be explained at our booth.