[End] Speaker at the Cell Culture Medium Symposium hosted by Shonan I-Park.

Supporting the development of advanced therapies at every stage, from research and development to application in humans.

Features and Benefits ■ Hydrophobic, forms a monolayer on the water surface, reducing surface adsorption ■ Prevents aggregation and minimizes instability by dispersing uniformly in solution ■ Scavenges free radicals and protects against oxidative stress ■ Functions as a pH buffer and nutrient source, supporting an optimal microenvironment for sustained cell survival ■ Supports cell viability during and after freeze preservation ■ A completely non-human and non-animal derived product, reducing logistical challenges

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Maximization of cell quality characteristics, assurance of reproducible results, reduction of development time.

You can check the following Sartorius culture solutions from this catalog: ■ Stem cell culture media, supplements, and reagents ■ Immune cell culture media ■ Recombinant human albumin and biopreservation ■ Other media and reagents ■ Growth factors and cytokines ■ HEK293 media portfolio ■ Services

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For protein production using CHO cell lines.

■ A wide range of products to accelerate media development ■ Sartorius' global manufacturing network that ensures supply ■ 100% known chemical composition, animal component-free, serum-free, and free of hydrolysates with high reproducibility ■ In addition to ready-to-use catalog products, customizable and highly flexible ■ Highly filterable and soluble media and feeds

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Introducing a medium system for protein production using the CHO system!

The starter kit for the culture system "4Cell XtraCHO" includes all the necessary culture components for cell acclimatization and fed-batch culture at a 3L capacity. When progressing to larger-scale cultures, all individual culture components are available in various forms, both liquid and powder. Using production media and feed media offers benefits such as "eliminating process variability and contamination risks." 【Customer Benefits】 ■ Production Efficiency: Ideal efficiency from bench scale to manufacturing scale ■ Compliance with Regulatory Guidelines: Eliminates process variability and contamination risks ■ Reduces Process Complexity: Facilitates purification *For more details, please refer to the PDF materials or feel free to contact us.

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Next-generation chemical components known to support Vero cell proliferation and virus production.

【Features】 ■ Effective for production: Achieves high cell proliferation and virus production in media with known chemical components ■ Efficient operation: Simplifies filtration and purification in downstream processes, improving virus productivity ■ Safety and regulatory compliance: Reduces variability between processes and minimizes contamination risks

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Excellent results and flexibility with xenofree serum-free medium for lymphocyte culture!

Cell-based immunotherapy is at the forefront of cancer treatment. The most common type of cell-based immunotherapy to date is T-cell therapy (with CAR-T and TIL being the mainstream). The cells used in immunotherapy are generally cultured in a medium supplemented with human serum. The use of serum introduces variability in the process due to individual differences among donors, leading to inconsistencies in cell growth and characteristics. By removing this serum and simplifying the process, regulatory risks are reduced, and the associated logistical burdens are alleviated. Nutri-T eliminates the need for serum by replacing its essential components with specific proteins, lipids, and other small molecules. <Product Overview> ■ Xeno-free ■ Serum-free, no serum supplementation required ■ Compliant with ISO13408 ■ For research use only ■ Developed using cells from actual cancer patients ■ Excellent results with PBMC, TIL, and CAR-T ■ Outstanding results at low initial seeding density

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Xeno-free serum-free medium for hES cells and hiPS cells

NutriStem hPSC XF will be registered with the U.S. FDA Drug Master File (DMF)! NutriStem hPSC XF medium is a xeno-free (XF) medium optimized for the culture of human iPS/ES cells. It contains no animal-derived components and is composed entirely of human-derived proteins. NutriStem hPSC XF Medium has the capability to culture human pluripotent cells without the need for high concentrations of bFGF or other stimulatory growth factors or cytokines, enabling long-term culture while maintaining undifferentiated potential under both feeder-free (Matrigel coated) and on-feeder (MEF, HFF) conditions.

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Redefining the excellence of stem cells and advancing clinical applications: a complete xenofree serum-free system for the proliferation and expansion of hMSCs.

MSC NutriStem XF medium is a xeno-free medium for human mesenchymal stem cells (MSC) derived from various tissues such as bone marrow, fat, and Wharton's jelly. It supports the long-term culture of human MSC while maintaining the fibroblast-like morphology, self-renewal ability, and multipotency observed in normal MSC. MSC Attachment Solution - Xeno-free, purified human fibronectin/fibrinogen - Optimized for serum-free culture - For the proliferation and differentiation of hMSC MSC Dissociation Solution - Ready-to-use, known chemical composition - Recombinant trypsin solution NutriFreez D10 Cryopreservation Solution - Known chemical composition, animal-derived component-free, protein-free - Excellent cell adhesion and viability

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Completely serum-free xenofree medium enables advanced adipogenesis, osteogenesis, and chondrogenesis from hMSCs.

MSCgo Xeno-Free Chondrogenic Differentiation Medium is an innovative xeno-free (free of animal-derived components) and serum-free medium designed to directly induce the differentiation of human mesenchymal stem cells (hMSC) from various sources into chondrocytes. A complete medium is prepared from a basic medium and a supplement mix that includes all the growth factors and supplements necessary for differentiation. Additionally, hMSC isolated and expanded with MSC NutriStemXF can be efficiently induced to differentiate into various cell types (fat, bone, cartilage).

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A cost-effective and efficient standardized supplement designed to adhere human mesenchymal stem cells under serum-free and xeno-free culture conditions.

NutriCoat Attachment Solution is a cell adhesion substrate designed for human mesenchymal stem cells (hMSC) based on human fibrinogen, suitable for serum-free and xeno-free culture. It is optimized for human MSC derived from various tissues cultured in MSC NutriStem XF Medium. Additionally, it supports long-term culture of hMSC and the results of colony-forming unit-fibroblast (CFU-F) assays under serum-free and xeno-free culture conditions. This product is a ready-to-use solution that can be stored at room temperature, making it ideal for experiments in cell therapy research.

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Serum-free, animal-derived component-free, protein-free short-term refrigerated (2-8 °C) cell preservation solution.

The cells stored in this solution demonstrate high recovery rates, normal cell characteristics, and excellent performance due to components that provide pH buffer, osmotic support, energy substrates, and ion concentration. ■ Ready-to-use ■ Known chemical composition, free from animal-derived components, serum-free, and protein-free ■ Provides maximum safety during low-temperature storage (2 - 8°C) ■ Ensures high survival and recovery rates after low-temperature storage ■ Ensures the safety of cells during transport ■ Suppresses necrosis and apoptosis after storage ■ Ideal for a wide range of applications ■ DMF preparation in progress ■ Surpasses competitors in the market

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An all-in-one solution designed for freezing and thawing cells, with a known chemical composition, particularly for cell therapy and clinical applications.

NutriFreez D5 Salt Based Cryopreservation Solution provides an environment that can protect cells even at ultra-low temperatures (-196°C), ensuring high survival rates, recovery rates, and performance for very delicate cells. It is manufactured under current GMP conditions and demonstrates industry-leading performance. This product is optimally formulated, containing 5% DMSO, and does not include antibiotics, antifungals, hormones, growth factors, serum, or proteins.

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Powerful cryopreservation medium optimized for various cells and tissues.

NutriFreez D10 freezing preservation medium is a ready-to-use cell freezing solution that is optimized for multiple cell lines, free of animal-derived components, serum-free, and protein-free. When culturing cells in a serum-free environment, it is important to maintain serum-free conditions during cell freezing and preservation. This product has been shown to have high efficiency in cell viability, proliferation, adhesion (in relevant cell lines), and physiological activity/expression even after freezing and thawing. It has demonstrated superior results compared to serum-containing freezing media and other serum-free products, making it an ideal product for both serum-containing and serum-free applications.

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High-quality raw materials for gene cell therapy manufacturing.

■ A smooth transition from the early development stage to the clinical stage with consistent quality and performance ■ Optimal cell proliferation and differentiation ensured by excellent batch-to-batch consistency ■ Regulatory support related to GMP products manufactured in compliance with applicable GMP guidelines

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Next, making cell research and manufacturing easier.

When using cells for large-scale high-quality production, the Sartorius SoloHill microcarriers offer many advantages: ■ Proven track record: Used for over 30 years in the pharmaceutical and healthcare industries for animals and humans. ■ Streamlined solution: Ready to use immediately after sterilization, no prior hydrophilization is required. ■ Ready for immediate use: Sterilized products have a Sterility Assurance Level (SAL) of 10-6, eliminating the need for sterility validation and shortening the manufacturing process.

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We would like to express our congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will be showcasing a number of products, including our new product, the Packaging Container Air Leak Test (Pin Hole Inspection) Device | MSQ-2003 series. We sincerely apologize for the inconvenience during your busy schedule, but we would like to cordially invite you to attend this event. 【 Trade Show Name 】 【 Dates 】 【 Venue/Booth Number 】

Yazaki Energy System will be exhibiting at the "14th Agricultural WEEK (commonly known as J-AGRI)" held at Makuhari Messe. In response to challenges surrounding agriculture, such as record heat and soaring energy prices, our company proposes an agricultural system that utilizes surplus solar heat and waste heat from factories during the summer to support stable cultivation throughout the year, from winter heating to summer cooling. ■ Exhibition Details (Booth Number: 25-47) <Closed-type Agricultural House> Results from the second season and initiatives for the third season <Localized Cooling in Solar-Powered Agricultural Houses> Mechanism of substrate cooling, comparison of energy consumption with spatial cooling, growth conditions this summer <Cooling and Heating with Solar Heat> Examples of crown heating and house cooling, utilization of surplus heat in summer <Cooling of Crops and Workers with Well Water> Exhibition of a prototype well water cooler and proposals for the use of cooling jackets When you visit, please be sure to stop by our booth.

We would like to inform you about the autumn and winter internship opportunities for the 2028 graduates. 1. Open Company Dates: October 23, 2026 (Friday), November 11, 2026 (Wednesday), December 10, 2026 (Thursday), January 21, 2027 (Thursday) Time: 13:30 - 15:30 Location: Online (Microsoft Teams) 2. 1-Day Job Experience Dates: November 17, 2026 (Tuesday), December 16, 2026 (Wednesday) January 15, 2027 (Friday), January 27, 2027 (Wednesday), February 4, 2027 (Thursday), February 10, 2027 (Wednesday), February 18, 2027 (Thursday) Time: 10:00 - 17:30 (tentative) Location: Takaya Corporation Headquarters (661-1 Ibara-cho, Ibara City, Okayama Prefecture)

Notice of participation in the "FOOD Expo 2026." 【Date and Time】 　November 11 (Wednesday) - 13 (Friday), 2026 　Opening hours: 10:00 AM - 5:00 PM 【Venue】 　Tokyo Big Sight 　East Hall 2, Booth Number B-36 【Exhibits】 　Cardboard insulated boxes 　Craft cooler cubes 　Vacuum insulated panel 　Pallet cubes

[Lecture Topics] 1. Co-creation Strategy to Deliver AI to the Field - Business Development and Joint Ventures in the Era of Generative AI and Physical AI Mr. Haruto Suzuki, Industrial and Regional Research Department, Development Bank of Japan 1. The Mechanism of Generative AI and Its Current Utilization by Companies 2. Expansion of the Generative AI Market and AI Infrastructure 3. Transition from Generative AI to Physical AI 4. Bottlenecks in Social Implementation and Solutions through Joint Ventures 5. Formation of an Implementation Ecosystem through Policy and Finance 6. Q&A / Business Card Exchange 2. Needs, Development Trends, Future Possibilities, and Challenges of Physical AI Mr. Kazushi Asama, Senior Researcher, Next-Generation Robot Research Organization, Waseda University / Emeritus Professor, University of Tokyo 1. What Physical AI Means 2. Needs for Physical AI and the Technological Trends of Generative AI Behind It 3. Development Trends of Physical AI 4. Future Possibilities and Challenges of Physical AI 5. Q&A / Business Card Exchange