Notice of participation in the 24th Annual Meeting of the Japanese Society for Regenerative Medicine from March 20 (Thursday) to March 22 (Saturday), 2025.

Reduce the risk of inflow and outflow of pollutants. Comprehensive support for facility development.

The "Room Pressure Control System" is our patented system (Patent No. 6773364) that allows for the sealing of decontamination rooms without disrupting the pressure balance with adjacent rooms in the same air conditioning system. By implementing this system, it is no longer necessary to stop the entire air conditioning system every time decontamination occurs, even in highly airtight rooms like cleanrooms, which also helps reduce the risk of contamination inflow and outflow. Additionally, our company can provide comprehensive support from planning to construction and maintenance for life science facilities such as pharmaceutical manufacturing facilities. [Our Strengths] - Proposals based on advanced technology grounded in experience and achievements, considering the entire equipment system. - We can also propose facility construction in compliance with the Pharmaceuticals and Medical Devices Act and the Act on Securing Safety for Regenerative Medicine. - Flexible responses to advanced needs such as room pressure management and aseptic management. *For more information about our company, please refer to the materials. Feel free to contact us as well.

• Pressure Control

For those considering the establishment or renovation of research facilities such as pharmaceutical manufacturing and cell culture processing, please feel free to consult with us! 【*Project examples are currently available.】

Our company plans, designs, and constructs clean rooms and related facilities under various conditions, ranging from life science facilities to medical facilities. By utilizing "digital mockups," we conduct virtual walkthroughs that allow us to visualize the flow of people and materials within the facility. You can confirm the 3D image of what the building will look like upon completion. This enables us to clearly envision detailed points that may only become apparent after completion (for example, "the workspace is good, but the changing area turned out to be surprisingly small," or "it became dark due to shadows from objects," etc.). [Features] - By utilizing digital mockups, you can virtually confirm the flow and completion image. - We propose facilities that comply with GMP, from flow planning to quality assurance. - We accommodate not only new constructions but also maintenance and renovations after operation. *For more details, please download the PDF or feel free to contact us.

• Other clean room equipment and facilities

Acquisition of a patent for "room pressure control technology" for cell culture processing facilities and establishment of a model room.

Our company plans, designs, and constructs clean rooms and related facilities under various conditions, ranging from life science facilities to medical facilities. We have obtained a patent for "room pressure control technology," which allows us to seal a decontamination room while maintaining pressure balance with adjacent rooms. In the model room established at our Tsukuba Mirai Technology Center, we can conduct tests on room pressure control for bio clean rooms, such as cell culture processing facilities. Additionally, we possess advanced technology and extensive know-how for the establishment and renovation of clean rooms in pharmaceutical manufacturing facilities and cell culture processing facilities, including "digital mock-up technology," which allows for virtual confirmation of the interior before construction. Please feel free to consult with us! For more details, such as case studies of cell culture processing facilities, please download the PDF or feel free to contact us.

• Clean Room

Advantech Toyo will be exhibiting at the trade show "JASIS 2026," which will be held at Makuhari Messe International Exhibition Hall. At this exhibition, manufacturers of analytical and scientific instruments will gather to showcase cutting-edge scientific and analytical systems and solutions. At our booth, we will display filter products for microbiological testing and environmental analysis, water quality testing products, pure and ultra-pure water production equipment, and culture-related equipment. Additionally, we will also showcase analytical balances from Mettler Toledo, along with equipment from other well-regarded manufacturers in the industry. Our sales and technical staff will be available to assist with product selection, so please feel free to stop by!

[Speakers] Nomura Research Institute, Ltd. Global Manufacturing Consulting Department Group Manager Hirokazu Shimo Senior Consultant Shoki Tokugawa Senior Consultant Wataru Hashimoto Consultant Masaaki Amano Consultant Tomoya Nakamura [Presentation Items] 1. Key Development Themes of Major OEMs 2. Development Approaches of Each OEM 2-1. Toyota 2-2. Tesla 2-3. Suzuki 2-4. Nissan 2-5. Honda 3. Development Approaches of Suppliers 4. Key Points for Strengthening Development Capabilities 5. Q&A / Business Card Exchange

[Speaker] Ayaka Motomura, Consultant, Business Transformation Unit, NTT Data Management Research Institute [Key Lecture Content] With the advancement of Physical AI, telecommunications carriers have the opportunity to evolve from being "companies that provide lines" to companies that connect and control AI and the physical world in real-time. This seminar will organize the changes in communication demand brought about by Physical AI and the business opportunities for telecommunications carriers, while explaining the role of AIOps as the first step towards entry. Furthermore, it will discuss strategies for monetizing in the Physical AI market by deploying the operational intelligence accumulated through AIOps to network APIs and industry-specific services, as well as the layers that telecommunications carriers should hold. [Lecture Topics] Chapter 1: The Competitive Structure of the "Real World" Rewritten by Physical AI Chapter 2: Reasons Why Opportunities for "Reversal" Arise for Telecommunications Carriers in the Era of Physical AI Chapter 3: The First Step Towards Physical AI Chapter 4: Shifting AIOps from "Defense" to "Offense" Chapter 5: The Layers to Hold in the Era of Physical AI [Q&A / Business Card Exchange]

[Instructor] Partner Ryoji Mori, Eichi Law Office [Key Lecture Content] This lecture will explain the revised Personal Information Protection Act of 2028. The three-year review this time is a major revision, and it is essential to first understand where and how the revisions have been made, as well as the overall picture of the amendments. Next, we will explain the individual amendments that are practically important. The key points are as follows, but it is important to note that both the strengthening and relaxation of obligations are occurring simultaneously, increasing overall complexity. At the time of the lecture, it is expected that subordinate laws and guidelines will not yet be published, but we will discuss points that require attention upon publication. We will distinguish between what is necessary across businesses and what varies by industry. [Lecture Items] 1. Expansion of consent exceptions: Relaxation of the difficulty of obtaining consent and expansion of academic research institutions 2. Statistical exceptions: System content and how to read complex provisions (plus learning about acceptability from controversies) 3. Strengthening regulations on biometric information and children's information: Caution required for age verification 4. Contactable personal-related information: Changes in external transmission responses 5. Review of outsourcing regulations: Addition and removal of obligations for contractors 6. Administrative fines: Narrow target range and low amounts (not worth fearing) 7. Q&A / Business card exchange

[Instructor] Innovation Analyst Andy Kondo [Key Lecture Content] *The latest content will be added (changed) as appropriate based on the on-site survey of IAA Transportation 2026.* From September 15 to 20, 2026, the largest commercial vehicle exhibition in Europe, IAA Transportation, will be held in Hanover, Germany. It is a gathering place for manufacturers of commercial vehicles such as trucks and buses, as well as the parts, energy, and software that support them, occurring every two years. The cost structure of logistics, urban transportation and the environment, energy transition, decarbonization efforts, and a microcosm of the industry will reveal the future business environment just a step ahead. In this seminar, an innovation analyst who has been observing major global exhibitions such as CES and Hannover Messe for many years will report shortly after the event based on on-site coverage. Has autonomous driving become the main focus in commercial vehicles? Where is the energy transition for large vehicles settling in terms of batteries, hydrogen, and alternative fuels? How far have Chinese companies come? Based on photos taken at the venue and observations of actual products, the seminar will delve into the implications for Japanese companies.