[Exhibition Information] 34th Annual Meeting of the Japanese Society of Circulatory Pharmacology

A world-class patch clamp system that is easy to operate for anyone, allowing for simple data acquisition and verification.

This is a patch clamp system of the world's smallest class that can perform gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. 【Features】 ■ No need for manual patch clamp experience or difficult operations ■ No need for microscope, vibration table, manipulator, Faraday cage, or puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent, ligand-dependent, and temperature-dependent channels ■ Options available for research on channel rhodopsins and mechanosensitive channels using light stimulation ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications and enables rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips ■ Optional temperature control (10 to 50°C), capable of extracellular/intracellular perfusion ■ Can be integrated with amplifiers such as HEKA and Axon *For details, please refer to the catalog available for download in PDF.

• Other physicochemical equipment
• Analytical Equipment
• Patch clamp system

A patch clamp system that incorporates a patch clamp amplifier, achieving miniaturization and reduction of installation costs, allowing for easy data acquisition and verification.

This is a world-class patch clamp system capable of performing gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. ■ No experience with manual patch clamping or difficult operations required ■ No need for microscope/vibration isolation table/manipulator/Faraday cage/puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent and ligand-dependent channels through pipetting ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications, enabling rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips

• Other physicochemical equipment
• Analytical Equipment
• Patch clamp system

Measurement of impedance and extracellular potential of iPS-derived cardiomyocytes.

This is a hybrid cardiotoxicity screening device capable of impedance measurement and extracellular potential measurement similar to MEA. It can detect not only cardiomyocytes but also the minute contractions of cancer cells and liver cells due to the effects of compounds. ■ Simultaneous measurement of impedance and extracellular potential ■ 96-well simultaneous measurement ■ Label-free measurement ■ Long-term monitoring capability ■ Electrical pacing & optical pacing (optional) ■ Comes with an incubation system (temperature, humidity, and CO2 control) ■ Includes multifunctional and excellent data analysis and graph creation software ■ Validated human iPS cells: iCell, iCell², AXOL CM, Cardiosight-S, MiraCell Cardiomyocytes, etc. ■ Compact desktop size: W20.5 x D18 x H11.7cm / 3.5kg (main unit)

• Other physicochemical equipment
• Other Analysis

The Langeendorff method has been transformed into the latest high-throughput technology, allowing for the measurement of contractile force in cardiomyocytes under physiological conditions similar to the natural environment of cardiac tissue.

The FLEXcyte 96, which transforms the conventional Langendorff method into the latest high-throughput technology, can measure the contractile force (mN/mm²) of cardiomyocytes for cardiotoxicity and safety evaluation, as well as drug screening, under physiological conditions similar to the native cardiac tissue environment, without missing even slight responses to cytotoxicity, regardless of whether in the chronic or acute phase, simultaneously in 96 wells. ■ Simultaneous measurement in 96 wells ■ Label-free measurement ■ Long-term monitoring possible ■ Optical pacing (optional) ■ Comes with an incubation system (temperature, humidity, CO2 control) ■ Includes multifunctional excellent data analysis and graphing software ■ Validated human iPS cells: iCell, iCell², AXOL CM, Cardiosight-S, MiraCell Cardiomyocytes, etc. ■ Compact desktop size: W20.5 x D18 x H11.7cm / 3.5kg (main unit)

• Other physicochemical equipment
• Other Analysis

Under physiological conditions, it is possible to measure the actual contractile force of iPS-derived cardiomyocytes.

Measurement of Contraction Force in Cardiomyocytes Using FLEXcyte96 The FLEXcyte membrane plate features a silicon membrane with a thickness of less than 10μm at the bottom of a 96-well plate. When cardiomyocytes are seeded onto the plate, the weight of the culture medium causes the silicon membrane to deflect, and subsequently, dynamic deflection (up and down movement) occurs due to the synchronized beating of the cardiomyocytes. By measuring the changes in deflection with our proprietary Capacitive Distance Sensor, developed in collaboration with innoVitro, it is possible to calculate mechanical stress and measure the actual contraction force under physiological conditions.

• Other physicochemical equipment
• Other Analysis

[Speaker] Kazuharu Yamamoto Partner Expert, Roland Berger Co., Ltd. [Key Lecture Content] In the automotive industry, the topic of EVs is ever-present. The advancement and promotion of EVs is a significant goal for achieving carbon neutrality (CN). On the other hand, the realization of CN and the progress of EVs are inseparable topics related to the realization of a circular economy (CE). In this lecture, I will present an overview of CE and CN, discuss the mechanisms of CE progressing in Europe, and the reverse supply chain, while also addressing the expansion of EVs and charging infrastructure from a consumer perspective. [Lecture Items] 1. Overview of CE and CN in the automotive industry and EVs 2. Mechanisms for achieving CE in Europe 3. Expansion of EVs and charging infrastructure (Characteristics of Japan within the global context) 4. Q&A / Business card exchange

[Speaker] Mitsune Shirasawa, Partner Attorney at TMI General Legal Practice [Key Lecture Content] The regulations that must be complied with when implementing payment businesses are defined by various laws, and it is common for the applicable laws to change due to subtle differences in the schemes adopted. Therefore, when building a business related to payments, it is essential to have not only an understanding of individual laws but also a cross-sectional understanding of how these laws interact with each other. Additionally, recent developments such as the categorization of money transfer businesses, the introduction of regulations regarding stablecoins, the clarification of payment collection services, and the emergence of new schemes like BNPL (Buy Now Pay Later) and BPSP (Business Payment Service Provider) have led to significant advancements and complexities in payment-related businesses. Thus, this seminar will provide a comprehensive explanation of the current regulations surrounding payment businesses and their practical responses. [Lecture Topics] 1. The environment surrounding payment legislation 2. Keywords related to payment and regulatory compliance 3. The overall picture of laws and regulations surrounding payments 4. Points to consider when building a business / When to consider potential conflicts with financial regulations 5. How to obtain permits and licenses related to payments 6. Q&A / Business card exchange

[Speaker] Yusuke Saiki Executive Officer, Consulting Division Head of Strategy & Innovation Unit Ignition Point Inc. [Key Lecture Content] As marketing becomes increasingly complex, the disconnect in "information, experience, and perspectives" between organizations, departments, and customer touchpoints has become a significant barrier to business growth. The key to overcoming this "era of division" lies in "co-creative marketing," which merges AI's analytical power with human creativity and empathy. In this lecture, we will introduce strategic approaches and specific actions based on practical examples of co-creative marketing that Ignition Point has supported. [Lecture Items] 1. The irreversible changes that AI brings to the business environment and the emergence of new challenges in marketing 2. Why is business growth being hindered in the digital age? 3. What is the key to overcoming division: "Co-creative Marketing Strategy"? 4. Based on Ignition Point's examples, the practice and strategic approach of "Co-creative Marketing Strategy" 5. Three steps to start implementing "Co-creative Marketing Strategy" from tomorrow 6. Q&A / Business card exchange

[Speaker] Yusuke Saiki Executive Officer, Consulting Division Head of Strategy & Innovation Unit, Ignition Point Inc. [Key Lecture Content] This presentation is aimed at solution sales professionals who feel the limitations of traditional, person-dependent sales methods. We will provide specific thinking methods, strategies, tools, and practical action plans to strategically leverage AI and shift from "passive problem-solving" to "active opportunity creation." Participants will gain insights and techniques to build a new sales style suitable for the AI era within their own sales organizations. [Lecture Items] 1. Why are changes occurring now in the sales environments of other companies? 2. The required transformation of sales styles 3. How to utilize generative AI to transform into proactive solution sales 4. Transitioning from problem-solving solution sales to problem-posing solution sales 5. Introduction and demonstration of practical tools and skills that can be used from today 6. Q&A / Business card exchange

[Key Lecture Content] 1. Overview of the grid-scale battery business and actual operations Kenji Eda, President of RAUL Co., Ltd. Director of the Energy Information Center 1. What is the grid-scale battery business? 2. Business revenue structure / various markets / subsidies, etc. 3. Flow from consideration of introduction to start of operation / points to note 4. Case studies of grid-scale batteries / introduction of actual cases 2. Business players in the grid-scale battery sector / specific company examples / Q&A for entry Hironobu Takeuchi, Manager of the Grid-Scale Battery Business Division at RAUL Co., Ltd. 1. Introduction to the classification of business players and their roles 2. Specific company examples for each player 3. Frequently asked questions and answers from entering companies 4. Q&A session / business card exchange