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  3. ライフィクスアナリティカル
  4. Monitoring and Control of Product Temperature Using Thermal Imaging During Continuous Freeze-Drying Process of Unit Dose Formulations - Aug 2019
OTHER
  • Jun 06, 2025
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Jun 06, 2025

Monitoring and Control of Product Temperature Using Thermal Imaging During Continuous Freeze-Drying Process of Unit Dose Formulations - Aug 2019

ライフィクスアナリティカル ライフィクスアナリティカル
In recent years, the pharmaceutical industry has rapidly advanced the development of biopharmaceuticals such as therapeutic proteins and vaccines. These drugs face challenges regarding stability in aqueous solution, which is why freeze-drying has become an essential technology for long-term storage. Traditional freeze-drying is conducted in a batch process that handles multiple vials at once, resulting in long processing times and high costs. Furthermore, controlling the freezing process is difficult, leading to variations in ice crystal size among vials, which causes inconsistencies in drying rates and poses challenges for ensuring product quality uniformity. Additionally, the heat distribution within the drying chamber is uneven, raising concerns about the risk of product collapse and quality variability. To address these issues, a new manufacturing technology called "continuous freeze-drying" has emerged in recent years. This technology combines continuous supply of raw materials with continuous discharge of products, achieving shorter processing times, cost reductions, and smaller equipment. Moreover, it reduces quality differences between vials, allowing for the efficient production of uniform and stable products. This groundbreaking technology has been further commercialized by RheaVita since its introduction in 2019, and in March 2025, a GMP-compliant system was implemented at their headquarters in Belgium.
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Product Temperature Monitoring and Control via Thermal Imaging during Continuous Freeze-Drying of Pharmaceutical Unit Doses
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RheaVita Corporation RheaLyo Mono System

Reduction of time/cost in process development and improvement of quality in freeze-drying of biopharmaceuticals.

The "RheaLyo Mono Single Vial Unit" is a freeze-drying device specifically designed for research and development, based on continuous freeze-drying technology. It is well-suited for very rapid formulation, process development, and optimization with minimal material consumption. From vial-level to continuous freeze-drying production lines (GMP Flex), it enables quick and easy process development and production scale-up based on numbering up. 【Features】 ■ Spin freeze vials that allow precise control of cooling rates ■ Control of primary freezing and secondary drying using infrared ■ Rapid freeze-drying is possible due to the thin product layer and large surface area ■ Complete monitoring, control, and inspection of vials ■ Reduction of quality variation for each vial *At the 2024 CPHI, RheaVita's GMP-Flex continuous freeze-drying system received the "Manufacturing Excellence" award! *For more details, please refer to the PDF document or feel free to contact us.

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Hyper CLT flooring panel

Easy-to-handle civil engineering CLT without the need for large cranes | Hyper CLT sheets

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In civil engineering sites, there are many instances where sheet boards are used for temporary roads, access roads, heavy machinery work yards, material storage areas, and pedestrian pathways. Traditional steel plates are heavy, which can require large cranes or heavy machinery for installation and removal, increasing the workload depending on site conditions. Hyper CLT sheet boards are civil engineering materials made from wooden CLT for civil use. The 5×10 board weighs about 230 kg, and the 5×20 board weighs about 460 kg, making them lightweight and easy to handle even with small machinery, which allows for easier installation without the need for large cranes. They also contribute to reducing the burden of transportation, installation, and removal, as well as improving maneuverability on site. Recommended as a registered technology by the Ministry of Land, Infrastructure, Transport and Tourism under NETIS "TH-250021-A," it is suitable for companies considering civil engineering, civil use, and civil CLT. This material is easy to use for creative proposals in public works, such as alternatives to steel plates, common temporary structures, temporary roads, and curing for material storage areas.

Jul 02, 2026

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Fukuda's leak test, leak inspection, leak detection, leak test, integrity test.

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Fukuda Co., Ltd. has been pursuing leak detection for 60 years and is committed to advancing the future of leak testing. 【 Supporting Various Leak Tests: Air Leak Test / Gas Leak Test (Hydrogen Gas, Helium Gas) 】 We develop, manufacture, and sell leak testing equipment to inspect airtightness and sealing properties. We will propose the appropriate testers and devices for each inspection target. 【 Target Industries and Examples of Inspection Targets 】 - Automotive Industry: Engines, FC components, valves and piping, various parts - Electronic Components Industry: Smartphones, keyless switches, various small sensors - Pharmaceuticals / Food / Cosmetics Industry: Bottle containers, syringes, vials, eye drop containers, pillow packaging, PTP packaging We will propose the most suitable leak testers for each industry. 【 ISO Certification 】JIS Q 9001:2015 (ISO 9001:2015)

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Same Sky Speaker, Micro Speaker New Products | CDS, CMS Series

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Our speaker lineup has expanded with the introduction of 16 new models. This release includes the first IPX7 waterproof speaker in the standard Φ28mm size and a wideband speaker with the lowest resonance frequency of 130Hz in the 40mm size. Additionally, we have introduced enclosure boxes for acoustic testing with 15 x 11mm, 16 x 9mm, and 18 x 13mm speakers, enhancing our support system to facilitate easier design and prototyping. Size: 20 x 8 x 3 mm to 40.2 x 40.2 x 24 mm Shape: Round, rectangular, square, oval Sound pressure: 81 dB to 106 dB Impedance: 4Ω to 8Ω Resonance frequency: 130Hz to 800Hz Mounting type: 200mm lead wire, solder pad

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[New Product Announcement] Sales of "AZ GUARDⓇ 8100FR" have begun!

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Notice of Summer Vacation 2026

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Dear Sir/Madam, I hope this message finds you well and thriving. I would like to express my sincere gratitude for your continued support. We would like to inform you that our company will be closed for summer vacation during the following period: ■ Summer Vacation Period From Saturday, August 8, 2026, to Sunday, August 16, 2026. We will resume normal operations on Monday, August 17, 2026. Inquiries received during the vacation period will be addressed sequentially after the start of business. We apologize for any inconvenience this may cause and appreciate your understanding.

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