[Exhibition Information] Membrane Symposium 2025

Easily measure channel activity at the molecular level.

【Measurement Target Examples】 Ion channels (voltage-dependent, ligand-dependent, temperature-sensitive), DNA nanopores, antimicrobial peptides, toxins, etc. In experiments using artificial lipid bilayers, the formation of lipid membranes, reconstitution of membrane proteins, and measurement of single-channel currents can be easily performed. Purified target membrane proteins (such as ion channels in vivo or artificial ion channels) can be reconstituted on artificially formed lipid bilayers, allowing for the evaluation of drug effects and functional/structural analysis. ■ Simultaneous formation and measurement of 4 channels of artificial lipid bilayers is possible ■ Lipid membranes can be formed with just pipetting operations ■ No need for microscope, vibration isolation table, manipulator, or Faraday cage ■ Direct reconstitution of target membrane proteins or membrane fusion with proteoliposomes ■ Temperature control (10–50°C) available (optional) ■ Palm-sized, easy connection via USB

• Other physicochemical equipment
• Analytical Equipment

Easily measure channel activity at the molecular level.

【Measurement Target Examples】 Ion channels (voltage-dependent, ligand-dependent, temperature-sensitive), DNA nanopores, antimicrobial peptides, toxins, etc. Experiments using artificial lipid bilayers allow for easy formation of lipid membranes, reconstitution of membrane proteins, and measurement of single-channel currents. It is possible to reconstitute purified target membrane proteins (such as ion channels found in vivo or artificial ion channels) on artificially formed lipid bilayers for drug action evaluation and functional/structural analysis. By rapidly and automatically forming 16-channel artificial lipid bilayers at once and conducting fully simultaneous measurements, researchers are freed from the burdens of the painting method in experiments using artificial lipid bilayers. ■ Simultaneous formation and measurement of 16-channel artificial lipid bilayers is possible ■ Automatic lipid membrane formation using a stirrer bar ■ No need for microscope, vibration isolation table, manipulator, or Faraday cage ■ Direct reconstitution of target membrane proteins or membrane fusion with proteoliposomes ■ Temperature control available (10–50°C)

• Other physicochemical equipment
• Analytical Equipment

A patch clamp system that incorporates a patch clamp amplifier, achieving miniaturization and reduction of installation costs, allowing for easy data acquisition and verification.

This is a world-class patch clamp system capable of performing gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. ■ No experience with manual patch clamping or difficult operations required ■ No need for microscope/vibration isolation table/manipulator/Faraday cage/puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent and ligand-dependent channels through pipetting ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications, enabling rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips

• Other physicochemical equipment
• Analytical Equipment
• Patch clamp system

A world-class patch clamp system that is easy to operate for anyone, allowing for simple data acquisition and verification.

This is a patch clamp system of the world's smallest class that can perform gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. 【Features】 ■ No need for manual patch clamp experience or difficult operations ■ No need for microscope, vibration table, manipulator, Faraday cage, or puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent, ligand-dependent, and temperature-dependent channels ■ Options available for research on channel rhodopsins and mechanosensitive channels using light stimulation ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications and enables rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips ■ Optional temperature control (10 to 50°C), capable of extracellular/intracellular perfusion ■ Can be integrated with amplifiers such as HEKA and Axon *For details, please refer to the catalog available for download in PDF.

• Other physicochemical equipment
• Analytical Equipment
• Patch clamp system

Kanadebia Co., Ltd. will be exhibiting at the "9th Railway Technology Exhibition 2025 Mass-Trans Innovation Japan 2025" held at Makuhari Messe. This exhibition has been held since 2010 as a comprehensive trade fair where various railway-related technologies, including railway and transportation systems, infrastructure technology, facilities, power, transportation, operation management, vehicles, interiors, and passenger services, come together. Please be sure to check out the "Railway Camera System" offered by Kanadebia. We sincerely look forward to your visit.

On November 20, 2025 (Thursday) and December 2, 2025 (Tuesday) from 11:00 to 14:00, our representative, certified public accountant and tax accountant Koichi Yokoyama, will be speaking at a free webinar hosted by Otsuka Shokai. He will explain important points to be aware of regarding the revised Construction Industry Law. [Construction Industry Law / Public Works Appropriateness Promotion Law] - Prevention of omissions in the description of construction contracts - Obligation to notify "risk" information before the contractor's contract - Mutual exchange of original documents for construction contracts - Digitization of estimates, contracts, and order forms/acceptance letters We are entering an era where contracts must be documented in writing and stored electronically. At Paperlogic, we fully support companies that are transitioning from paper to digital. We also offer free consultations with certified public accountants and tax accountants, so please join us!

We would like to inform you that we will be exhibiting our products at the Membrane Symposium 2025. If you are planning to attend, please feel free to stop by. ❚ Products Scheduled for Exhibition - Artificial Lipid Bilayer Experimental Device | Orbit mini You can easily measure channel activity at the single-molecule level. This device allows for the formation of lipid membranes, reconstitution of membrane proteins, and single-channel measurements in experiments using artificial lipid bilayers, all performed with just a micropipette, enabling functional and structural analysis of target membrane proteins and evaluation of drug effects. - Liposome Preparation Device | Vesicle Prep Pro This is the world's first device that can produce giant unilamellar vesicles (GUVs) with diameters ranging from 1 to 30 μm without organic solvents, using the electroporation method (vibrating hydrated lipid films in an alternating electric field). - Auto Patch Clamp System | Port-a-Patch mini This compact system eliminates the need for a microscope, vibration isolation table, manipulator, and Faraday cage, which are typically required for conventional patch clamp experiments. It allows for easy data acquisition and verification without the need for specialized skills or experience.

Agilent will be exhibiting at the "VACUUM 2025 Vacuum Exhibition"! At Agilent, we offer clean and quiet IDP dry scroll pumps, high-performance and high-compression TwisTorr turbo pumps, ion pumps and controllers optimized for UHV/XHV, and robust and reliable helium leak detectors. Leveraging the technology and expertise cultivated at Varian Vacuum, we respond to our customers' vacuum needs with the value of our products and support based on extensive experience and knowledge. Agilent's pumps, systems, and components enable cutting-edge research in physics, analytical instruments, and nanotechnology, and are also ideal for industrial processes. We invite you to visit the Agilent booth! 【Exhibition Information】 Date: December 3 (Wed) - 5 (Fri), 2025, 10:00 - 17:00 Venue: Tokyo Big Sight, South Hall 2 Booth Number: V-36

＼ Make electrical design easier with comprehensive electrical design CAD Eplan! ／ At this exhibition, under the theme "Data collaboration from design to manufacturing! Significant reduction of lead time in control panel manufacturing through digitalization," we will introduce how Eplan and Rittal can enhance the efficiency of electrical design and control panel manufacturing. We will provide information that can assist you in all processes from design to manufacturing, including the efficiency and automation of electrical design and the manufacturing process of control panels utilizing digital twins. If you are struggling with electrical design or considering the introduction of electrical design CAD, please visit the Eplan and Rittal booth. Date: November 19 (Wed) to November 21 (Fri), 2025, 10:00 AM to 5:00 PM Venue: Tokyo Big Sight, East Hall 4, 4-05 Attendance at "IIFES 2025" requires complete advance registration, so please apply on the official exhibition website. "IIFES 2025" official website: https://iifes.jp/