Notice of Participation in COSME Week 2026 / 16th Cosmetics Development Exhibition

Natural anionic surfactant upcycled from coffee by-products.

To produce 1 kilogram of coffee, 20 kilograms of CO2 are required. However, only 1% of the coffee beans are used in the production process, while 99% is discarded. Cafe Bueno has achieved zero waste by utilizing this residue as a cosmetic ingredient. KLEANSTANT is a natural anionic surfactant upcycled from coffee by-products, containing potassium palmitate, linoleic acid, polyphenols, tocopherols, and diterpene esters. In addition to its cleansing properties, foaming ability, and antioxidant effects, it also has moisturizing benefits. KLEANSTANT exhibits high foaming performance when the original pH is lowered through neutralization treatment. It shows the best performance at a pH of 5 to 6, and citric acid also contributes to the removal of residues and improvement of emulsification. However, at a pH of 4, foaming ability may decrease.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

A scrub made from upcycled coffee beans. It has a mild texture due to particle size being below 150μm. It can be used for coloring formulations.

It is said that 20 kilograms of CO2 are needed to produce 1 kilogram of coffee. However, only 1% of the coffee beans are used in production, while 99% is discarded. Cafe Bueno has achieved zero waste by using this residue as a cosmetic ingredient. KAFFIBRE is a natural scrub expected to be a substitute for microplastics. It features a particle size of less than 150μm, making it easy to incorporate into formulations.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

An extract containing melanoidin. It has UV absorption effects and suppresses the production of glycation substances. Anti-aging effects (improvement of spots and wrinkles).

To produce 1 kilogram of coffee, 20 kilograms of CO2 are required. However, only 1% of the coffee beans are used in production, while 99% is discarded. Cafe Bueno has achieved zero waste by using this residue as a cosmetic ingredient. KAFFEAGE is a powdered extract product that has powdered the water-soluble active ingredients contained in coffee residue. It contains polyphenols and melanoidins. Efficacy: UV Protection: Confirmed absorption in the UV range, suppresses the production of glycation substances caused by UV. SPF Boost: +73.9% (1.8% added) Crow's Feet Wrinkles: -12% Elasticity Improvement: +12.2% Moisturizing Effect: +16.37%

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

A lipid-soluble hyaluronic acid sodium derivative with caprylic acid introduced. It can be used in oil products for hair care, skin care, and lip care.

<About Contipro> It is a biotechnology company and a global manufacturer that has been producing active ingredients used in the pharmaceutical and cosmetic industries for nearly 30 years. We offer a range of products including sodium hyaluronate and its derivatives produced by fermentation, as well as distinctive peptides and natural polysaccharides. <Product Introduction> This is an oil-soluble sodium hyaluronate derivative with caprylic acid. It can be used in oil phases for lip products, balms, hair oils, nail care, and more. <Efficacy> - Stimulates hair growth - Improves cuticles - Increases lip volume - Improves elasticity - Reduces wrinkles: 35% - Shrinks pores: 30% - Smoothing effect - Reduces erythema: over 10% and more.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

Hyaluronic Acid Na for Whitening that Maximizes the Function of Alpha-Linolenic Acid

HyWhite is a sodium hyaluronate with whitening (brightening) properties manufactured by Contipro in the Czech Republic. HyWhite is a product that has high whitening (brightening) effects, made by partially replacing low molecular weight sodium hyaluronate with alpha-linolenic acid, which has high permeability to the skin. Alpha-linolenic acid is widely known for its strong melanin production suppression effects, and in in-vitro results, it has been confirmed to have a higher suppression effect than kojic acid. On the other hand, it is also known as a component that is difficult to formulate due to its low skin permeability and instability. This product promotes the absorption of alpha-linolenic acid, which has been a problem in the past, by replacing part of the low molecular weight hyaluronate with alpha-linolenic acid, thereby improving stability and maximizing the effects of alpha-linolenic acid. *In addition to HyWhite, Contipro also manufactures sodium hyaluronate, hydrolyzed sodium hyaluronate, and other hyaluronate derivatives.

• Other additives
• Cosmetic materials and raw materials

It is a porous silica micro powder derived from bamboo. It has improved usability, sebum absorption effects, shine suppression, and deodorizing effects.

This is silica derived from bamboo originating in the forests of India. Properties: White powder Particle size: ≦15μm Silica content: ≦87% Mechanism of action: The porous particles of fine micro powder absorb excess sebum and sweat, reducing shine and drying sweat. Effectiveness: - Reduces skin oiliness and controls shine, improving makeup longevity. - Absorbs sweat and keeps the skin dry, thus reducing odor. In Vitro: Artificial sebum absorption capacity: Twice its own weight In Vivo: Antiperspirant effect: -26% (after 4 hours) Odor suppression: -40% (after 4 hours)

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

Ginger root extract containing gingerol, which has whitening effects, longevity effects, stress resistance, antioxidant properties, and calming effects.

This is an oil extract made from ginger roots sourced from Madagascar, extracted with triheptanoin. LUMILYS suppresses lipofuscin and melanin, the root causes of age-related spots, through both traditional and new mechanisms of action. Old mechanism: It suppresses the production of lipofuscin and melanin through antioxidant and anti-inflammatory effects. New mechanism: By inhibiting growth factor SCF and nerve factor RGMB, it directly acts on melanocytes to fundamentally control melanin production. *RGMB is a factor secreted from nerves when they interact with melanocytes (LUMILYS acts on the nerves). Active ingredients: • Gingerol: >32%/dry weight *A component that possesses whitening effects, longevity effects, stress resistance, antioxidant effects, and calming effects (6-gingerol: >20%, 8-gingerol: >4%, 10-gingerol: >4%) Efficacy: Antioxidant: EC50: 0.25% IL8: -46% Reactive oxygen species: -46.5% Growth factor SCF: -27% Nerve factor RGMB: -12% Lipofuscin accumulation: -26% Melanin production: -46% Currently conducting In Vivo studies.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

Extreme environment microorganisms, long-lasting moisture, UV protection, Langerhans cell protection, anti-pollution, anti-aging, fermentation, hair care.

<Ectoin Natural Features> Ectoin is a type of cyclic amino acid produced by extremophilic microorganisms (Halomonas) that inhabit salt lakes and deserts. It has 4 moles of bound water per 1 mole of Ectoin, exhibiting cosmotropic properties. This characteristic contributes to the stabilization of interactions between water molecules, forming a hydrocomplex. This hydrocomplex helps stabilize biological structures (such as cells, proteins, enzymes, and nucleic acids) against environmental stresses like temperature changes, high salt concentrations, strong UV radiation, and dehydration. ― About Effectiveness ― Moisturizing Persistence (In-Vivo): Lasts for 1 week. Skin Barrier Function and Protection of Langerhans Cells (In-Vivo): 100% protection. Promotion of Heat Shock Protein Production (In-Vitro), Anti-Pollution Effect (Ex-Vivo), Protection against Blue Light, UV-A, UV-B, IR-A, and Heat, Anti-Aging Effects (In-Vivo): Improvement in Skin Roughness (86% improvement), Wrinkle Depth (32% improvement), Elasticity (82% improvement), Smoothness (61% improvement), Whitening Effect (In-Vivo): Improvement in Skin Pigmentation (25% improvement).

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

We will be exhibiting at the "Food Industry Creation Exhibition '25" scheduled to be held from May 14 (Wednesday) to May 16 (Friday) at Marine Messe Fukuoka. We will showcase measuring instruments ideal for food quality and hygiene management, such as fryer oil deterioration testers and food thermometers. Our instruments can connect to the mobile app testo Smart, allowing you to save measurement values in the app and document them in PDF format, supporting the efficiency of daily fryer oil and temperature management tasks!

The Pharmaceutical and Cosmetic Manufacturing Exhibition is the largest international exhibition in Japan for the pharmaceutical and cosmetic manufacturing sector, featuring 900 companies from both domestic and international markets and attracting 34,000 attendees. A wide range of products and services supporting the pharmaceutical and cosmetic manufacturing processes will be showcased, including manufacturing and packaging, plant engineering, CMO/CDMO, measurement and inspection, sterilization and cleaning, logistics and distribution. We will be waiting for you with a wide selection of environmental monitoring systems, including testo Saveris 1 and data loggers.

In the field of powder technology that supports cutting-edge technology, it is essential to efficiently stir and degas slurry materials that exhibit complex flow behavior and dispersion characteristics, as well as to understand their flow and dispersion properties in the original liquid state. This seminar aims to teach the latest technologies of the "Awatori Nentaro," a mixer renowned for stirring and degassing high-concentration and high-viscosity materials, and the "MCR Rheometer," which allows for the evaluation of complex flow and dispersion characteristics of slurry materials without dilution, while also providing hands-on experience with the actual equipment. Additionally, we will hold a consultation session regarding any troubles or evaluation methods you may currently be facing. We look forward to your participation. Target Audience: Customers currently using Anton Paar Japan and Shinki products, as well as those considering their introduction. Customers interested in stirring, degassing, and rheological measurement.

[Key Lecture Content] 1. Initiatives to Promote the Introduction of Next-Generation Fuels Ministry of Economy, Trade and Industry Agency for Natural Resources and Energy Resource and Fuel Department Fuel Supply Infrastructure Division Assistant Manager Kaori Higashitani 1. The Necessity of Carbon-Neutral Fuels 2. Synthetic Fuels and Biofuels 3. Current Status and Challenges of Introducing Bioethanol into Gasoline 4. Initiatives for Expanding the Introduction of Bioethanol into Gasoline 5. Q&A / Business Card Exchange 2. Decarbonization of Automotive Fuels - Directions and Challenges for Decarbonizing Gasoline Vehicles - Professor, Aichi Institute of Technology Member, Subcommittee on Decarbonized Fuel Policy, Ministry of Economy, Trade and Industry Member, Carbon Management Subcommittee, etc. Motohiro Kondo 1. Direction of Automotive Powertrains 2. Effects of Bioethanol Blended Gasoline - Adoption Status and Future Outlook in Other Countries - Market for Bioethanol Blended Gasoline 3. Response Measures and Challenges for Vehicles and Infrastructure - Vehicle Adaptation - Supply Chain Response - Standards and Regulatory Compliance 4. Technological Trends in Decarbonized Fuels 5. Summary 6. Q&A / Business Card Exchange

[Speaker] Ryōhei Nomoto, Director, GLOBIS Capital Partners, Inc. [Key Lecture Content] This lecture will dismantle the myth that new businesses and innovations are "creations from scratch" and will elucidate the mechanisms of "value transfer," which is a source of immense wealth. The essence of excellent business lies in mediating resources that are undervalued in one place to another place where they are highly valued, thereby generating profit. Through practical frameworks such as "separation of ecosystems," "redefinition of resources," and "building checkpoints," this presentation will comprehensively analyze everything from large global corporations to domestic startups, offering key insights on how to build "strong" businesses in the AI era and beyond. [Lecture Items] 1. The trap of "zero-one faith" and the assumptions of business "common sense" 2. The mechanisms and theoretical background of "value transfer" 3. The "three pillars" that establish "value transfer" 4. Three tools for building "checkpoints" 5. Dissection of modern business (case studies) 6. The "side effects" of value transfer and future frontiers 7. Q&A / Business card exchange