Notice of Participation in COSME Week 2026 / 16th Cosmetics Development Exhibition

Natural anionic surfactant upcycled from coffee by-products.

To produce 1 kilogram of coffee, 20 kilograms of CO2 are required. However, only 1% of the coffee beans are used in the production process, while 99% is discarded. Cafe Bueno has achieved zero waste by utilizing this residue as a cosmetic ingredient. KLEANSTANT is a natural anionic surfactant upcycled from coffee by-products, containing potassium palmitate, linoleic acid, polyphenols, tocopherols, and diterpene esters. In addition to its cleansing properties, foaming ability, and antioxidant effects, it also has moisturizing benefits. KLEANSTANT exhibits high foaming performance when the original pH is lowered through neutralization treatment. It shows the best performance at a pH of 5 to 6, and citric acid also contributes to the removal of residues and improvement of emulsification. However, at a pH of 4, foaming ability may decrease.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

A scrub made from upcycled coffee beans. It has a mild texture due to particle size being below 150μm. It can be used for coloring formulations.

It is said that 20 kilograms of CO2 are needed to produce 1 kilogram of coffee. However, only 1% of the coffee beans are used in production, while 99% is discarded. Cafe Bueno has achieved zero waste by using this residue as a cosmetic ingredient. KAFFIBRE is a natural scrub expected to be a substitute for microplastics. It features a particle size of less than 150μm, making it easy to incorporate into formulations.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

An extract containing melanoidin. It has UV absorption effects and suppresses the production of glycation substances. Anti-aging effects (improvement of spots and wrinkles).

To produce 1 kilogram of coffee, 20 kilograms of CO2 are required. However, only 1% of the coffee beans are used in production, while 99% is discarded. Cafe Bueno has achieved zero waste by using this residue as a cosmetic ingredient. KAFFEAGE is a powdered extract product that has powdered the water-soluble active ingredients contained in coffee residue. It contains polyphenols and melanoidins. Efficacy: UV Protection: Confirmed absorption in the UV range, suppresses the production of glycation substances caused by UV. SPF Boost: +73.9% (1.8% added) Crow's Feet Wrinkles: -12% Elasticity Improvement: +12.2% Moisturizing Effect: +16.37%

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

A lipid-soluble hyaluronic acid sodium derivative with caprylic acid introduced. It can be used in oil products for hair care, skin care, and lip care.

<About Contipro> It is a biotechnology company and a global manufacturer that has been producing active ingredients used in the pharmaceutical and cosmetic industries for nearly 30 years. We offer a range of products including sodium hyaluronate and its derivatives produced by fermentation, as well as distinctive peptides and natural polysaccharides. <Product Introduction> This is an oil-soluble sodium hyaluronate derivative with caprylic acid. It can be used in oil phases for lip products, balms, hair oils, nail care, and more. <Efficacy> - Stimulates hair growth - Improves cuticles - Increases lip volume - Improves elasticity - Reduces wrinkles: 35% - Shrinks pores: 30% - Smoothing effect - Reduces erythema: over 10% and more.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

Hyaluronic Acid Na for Whitening that Maximizes the Function of Alpha-Linolenic Acid

HyWhite is a sodium hyaluronate with whitening (brightening) properties manufactured by Contipro in the Czech Republic. HyWhite is a product that has high whitening (brightening) effects, made by partially replacing low molecular weight sodium hyaluronate with alpha-linolenic acid, which has high permeability to the skin. Alpha-linolenic acid is widely known for its strong melanin production suppression effects, and in in-vitro results, it has been confirmed to have a higher suppression effect than kojic acid. On the other hand, it is also known as a component that is difficult to formulate due to its low skin permeability and instability. This product promotes the absorption of alpha-linolenic acid, which has been a problem in the past, by replacing part of the low molecular weight hyaluronate with alpha-linolenic acid, thereby improving stability and maximizing the effects of alpha-linolenic acid. *In addition to HyWhite, Contipro also manufactures sodium hyaluronate, hydrolyzed sodium hyaluronate, and other hyaluronate derivatives.

• Other additives
• Cosmetic materials and raw materials

It is a porous silica micro powder derived from bamboo. It has improved usability, sebum absorption effects, shine suppression, and deodorizing effects.

This is silica derived from bamboo originating in the forests of India. Properties: White powder Particle size: ≦15μm Silica content: ≦87% Mechanism of action: The porous particles of fine micro powder absorb excess sebum and sweat, reducing shine and drying sweat. Effectiveness: - Reduces skin oiliness and controls shine, improving makeup longevity. - Absorbs sweat and keeps the skin dry, thus reducing odor. In Vitro: Artificial sebum absorption capacity: Twice its own weight In Vivo: Antiperspirant effect: -26% (after 4 hours) Odor suppression: -40% (after 4 hours)

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

Ginger root extract containing gingerol, which has whitening effects, longevity effects, stress resistance, antioxidant properties, and calming effects.

This is an oil extract made from ginger roots sourced from Madagascar, extracted with triheptanoin. LUMILYS suppresses lipofuscin and melanin, the root causes of age-related spots, through both traditional and new mechanisms of action. Old mechanism: It suppresses the production of lipofuscin and melanin through antioxidant and anti-inflammatory effects. New mechanism: By inhibiting growth factor SCF and nerve factor RGMB, it directly acts on melanocytes to fundamentally control melanin production. *RGMB is a factor secreted from nerves when they interact with melanocytes (LUMILYS acts on the nerves). Active ingredients: • Gingerol: >32%/dry weight *A component that possesses whitening effects, longevity effects, stress resistance, antioxidant effects, and calming effects (6-gingerol: >20%, 8-gingerol: >4%, 10-gingerol: >4%) Efficacy: Antioxidant: EC50: 0.25% IL8: -46% Reactive oxygen species: -46.5% Growth factor SCF: -27% Nerve factor RGMB: -12% Lipofuscin accumulation: -26% Melanin production: -46% Currently conducting In Vivo studies.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

Extreme environment microorganisms, long-lasting moisture, UV protection, Langerhans cell protection, anti-pollution, anti-aging, fermentation, hair care.

<Ectoin Natural Features> Ectoin is a type of cyclic amino acid produced by extremophilic microorganisms (Halomonas) that inhabit salt lakes and deserts. It has 4 moles of bound water per 1 mole of Ectoin, exhibiting cosmotropic properties. This characteristic contributes to the stabilization of interactions between water molecules, forming a hydrocomplex. This hydrocomplex helps stabilize biological structures (such as cells, proteins, enzymes, and nucleic acids) against environmental stresses like temperature changes, high salt concentrations, strong UV radiation, and dehydration. ― About Effectiveness ― Moisturizing Persistence (In-Vivo): Lasts for 1 week. Skin Barrier Function and Protection of Langerhans Cells (In-Vivo): 100% protection. Promotion of Heat Shock Protein Production (In-Vitro), Anti-Pollution Effect (Ex-Vivo), Protection against Blue Light, UV-A, UV-B, IR-A, and Heat, Anti-Aging Effects (In-Vivo): Improvement in Skin Roughness (86% improvement), Wrinkle Depth (32% improvement), Elasticity (82% improvement), Smoothness (61% improvement), Whitening Effect (In-Vivo): Improvement in Skin Pigmentation (25% improvement).

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

When we look around us, we see various areas such as housing, home appliances, automobiles, miscellaneous goods, and sports equipment filled with many plastic materials like synthetic fibers, films, bottles, and resin products. However, the concept of modern polymer materials, specifically the idea of polymers (macromolecules) connected by covalent bonds, was not established just 100 years ago. Therefore, it can be said that in less than a century, numerous plastic materials with various characteristics have been developed and rapidly integrated into our lives. Due to the short history and the diversity of materials, there are various challenges encountered when dealing with plastic materials, and the role of analytical technicians in solving these issues is significant. In this course, we will explain important and fundamental points over two sessions, focusing on the field of resin materials, not only for analytical technicians but also for engineers who create products using plastic materials and those who use plastic products to deepen their understanding. In the first session, which serves as a foundational overview, we will discuss the characteristics of representative plastic materials, including molecular structure and physical properties, characteristics and applications, and manufacturing methods, to aid in the understanding of plastic materials.

When we look around us, we see that various areas such as housing, home appliances, automobiles, miscellaneous goods, and sports equipment are overflowing with many plastic materials like synthetic fibers, films, bottles, and resin products. However, 100 years ago, the concept of modern polymer materials, specifically the idea of polymers (macromolecules) connected by covalent bonds, had not yet been established. Therefore, it can be said that in just under a century, numerous plastic materials with various characteristics have been developed and rapidly integrated into our lives. Due to the short history and the diversity of materials, there are various challenges encountered when handling plastic materials, but the role of analytical technicians in solving these issues is significant. Following the previous foundational edition, this second application edition will explain polymer multiphase materials (such as polymer alloys, compounds, and resin composites) and molding techniques, as well as environmental issues surrounding plastic materials, in order to enhance the practical value of plastic materials.

[Instructor] Yosuke Okada, President of Activation Consulting Co., Ltd. [Key Lecture Content] As work styles diversify, the difficulty of personnel evaluation is increasing. While there is an effort to motivate subordinates, it is often heard that repeated meetings without proper "evaluation techniques" can lead to increased dissatisfaction. This course will convey the "evaluation techniques" practiced by effective managers for those struggling with the evaluation and development of their subordinates. By learning "evaluation techniques," participants will understand eye-opening "ways of thinking" to gain the trust of their subordinates and will be able to motivate them to carve out their own careers. The instructor has guided over 100 companies as a "personnel evaluation consultant." Many have noted that his book "The Techniques to Become a Valued Employee" articulates the true feelings of managers. [Lecture Items] 1. Essential "evaluation techniques" for future managers 2. The essence of personnel evaluation that no one teaches 3. Methods to motivate subordinates to carve out their own careers 4. Immediately usable personnel evaluation techniques 5. Q&A

Our company will be exhibiting at the 23rd Annual Meeting of the Japanese Society of Reproductive Psychology, which will be held at the Urban Center Hotel. The event will take place in person. We sincerely look forward to the participation of many attendees.

We will be exhibiting at the 47th Kinki Academic Conference of the Japan Hospital Pharmacists Association held at Grand Cube Osaka. The conference will be held in person. We sincerely look forward to the participation of many attendees.