[Exhibition Information] 103rd Annual Meeting of the Japanese Physiological Society

A patch clamp system that incorporates a patch clamp amplifier, achieving miniaturization and reduction of installation costs, allowing for easy data acquisition and verification.

This is a world-class patch clamp system capable of performing gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. ■ No experience with manual patch clamping or difficult operations required ■ No need for microscope/vibration isolation table/manipulator/Faraday cage/puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent and ligand-dependent channels through pipetting ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications, enabling rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips

• Other physicochemical equipment
• Analytical Equipment
• Patch clamp system

A world-class patch clamp system that is easy to operate for anyone, allowing for simple data acquisition and verification.

This is a patch clamp system of the world's smallest class that can perform gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. 【Features】 ■ No need for manual patch clamp experience or difficult operations ■ No need for microscope, vibration table, manipulator, Faraday cage, or puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent, ligand-dependent, and temperature-dependent channels ■ Options available for research on channel rhodopsins and mechanosensitive channels using light stimulation ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications and enables rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips ■ Optional temperature control (10 to 50°C), capable of extracellular/intracellular perfusion ■ Can be integrated with amplifiers such as HEKA and Axon *For details, please refer to the catalog available for download in PDF.

• Other physicochemical equipment
• Analytical Equipment
• Patch clamp system

Easily measure channel activity at the molecular level.

【Measurement Target Examples】 Ion channels (voltage-dependent, ligand-dependent, temperature-sensitive), DNA nanopores, antimicrobial peptides, toxins, etc. In experiments using artificial lipid bilayers, the formation of lipid membranes, reconstitution of membrane proteins, and measurement of single-channel currents can be easily performed. Purified target membrane proteins (such as ion channels in vivo or artificial ion channels) can be reconstituted on artificially formed lipid bilayers, allowing for the evaluation of drug effects and functional/structural analysis. ■ Simultaneous formation and measurement of 4 channels of artificial lipid bilayers is possible ■ Lipid membranes can be formed with just pipetting operations ■ No need for microscope, vibration isolation table, manipulator, or Faraday cage ■ Direct reconstitution of target membrane proteins or membrane fusion with proteoliposomes ■ Temperature control (10–50°C) available (optional) ■ Palm-sized, easy connection via USB

• Other physicochemical equipment
• Analytical Equipment

Easily measure channel activity at the molecular level.

【Measurement Target Examples】 Ion channels (voltage-dependent, ligand-dependent, temperature-sensitive), DNA nanopores, antimicrobial peptides, toxins, etc. Experiments using artificial lipid bilayers allow for easy formation of lipid membranes, reconstitution of membrane proteins, and measurement of single-channel currents. It is possible to reconstitute purified target membrane proteins (such as ion channels found in vivo or artificial ion channels) on artificially formed lipid bilayers for drug action evaluation and functional/structural analysis. By rapidly and automatically forming 16-channel artificial lipid bilayers at once and conducting fully simultaneous measurements, researchers are freed from the burdens of the painting method in experiments using artificial lipid bilayers. ■ Simultaneous formation and measurement of 16-channel artificial lipid bilayers is possible ■ Automatic lipid membrane formation using a stirrer bar ■ No need for microscope, vibration isolation table, manipulator, or Faraday cage ■ Direct reconstitution of target membrane proteins or membrane fusion with proteoliposomes ■ Temperature control available (10–50°C)

• Other physicochemical equipment
• Analytical Equipment

The "International Fermentation and Brewing Food Industry Exhibition" is Japan's only specialized exhibition that brings together ingredients, materials, research equipment, manufacturing facilities, testing equipment, and packaged products related to fermentation and brewing. In 2013, "Washoku" (Japanese cuisine) and in 2024, "Traditional Sake Brewing" were registered as UNESCO Intangible Cultural Heritage, increasing interest in Japan's fermentation and brewing industry. This exhibition will be grandly held at Tokyo Big Sight as a platform to promote the development of the industry and the richness of food culture to the world, and to spread Japan's proud fermented and brewed foods.

Gathering the wisdom of the DOWA Group towards the realization of a decarbonized society! We would like to introduce the initiatives of each DOWA Group company. We look forward to seeing you at our booth!

Heat pipes are passive heat transfer devices that utilize latent heat of vaporization in a two-phase system and do not require driving energy. Heat pipes have very high thermal conductance, with their equivalent thermal conductivity being several hundred times higher than that of a copper rod of the same size. The primary application of heat pipes is in the cooling of computers and electronic products. Recently, AI servers and data centers have gained attention; for example, nVidia's GPUs can reach heat generation of up to 1 kW, employing water-cooled cold plates and 3D vapor chambers. Air cooling is limited to 800 W, while nVidia's Ruben GPU can reach 2 kW, utilizing water-cooled microchannel cold plates, among others. In response to further increases in heat generation, vapor chamber composite cold plates, two-phase pump loop cooling, and impingement cooling have been developed. Additionally, recent cooling cases for batteries, motors, and IGBTs in electric vehicles will be discussed.

In the past, thermal design primarily focused on complex heat transfer through convection and radiation to the atmosphere. However, with the increase in surface-mounted components and power density, the heat dissipation pathways are gradually shifting to thermal conduction through substrates and enclosures. One of the key heat dissipation devices to promote heat transfer in limited spaces is TIM (Thermal Interface Material). A wide variety of TIMs have been developed in the market, and in recent years, key areas where TIMs are widely used include AI data centers and automotive equipment centered around electric vehicles (EVs). In this course, we will first explain the overview of heat dissipation design in AI data centers and automotive equipment, and in the latter half, we will provide a detailed explanation of the thermal and mechanical properties of TIMs in these two fields, as well as important considerations when selecting TIMs.

An explanation of the economic viability, technology, projects, and industry trends and outlook for thermal energy storage and thermoelectric batteries, which are attracting attention for their use in unused heat utilization, energy storage, and renewable energy load leveling. Part 1 Technological and business outlook for thermal energy storage and thermoelectric batteries both domestically and internationally Part 2 Fundamentals, components, technology, and application outlook of thermophotovoltaic (TPV) power generation systems