Notice of Participation and Luncheon Seminar at the 26th Annual Meeting of the Japanese Society for Protein Science

Accurately evaluate the FcRn-IgG binding that affects the half-life extension of antibodies! Introducing assay design and best practices.

This document is an application note summarizing the analysis method for FcRn-antibody interactions using the "Octet" biomolecular interaction analysis system. The binding of the Fc region of human IgG antibodies to the neonatal Fc receptor (FcRn) affects the biological and pharmacological properties of antibodies, such as extending the half-life. By altering this binding, it is possible to extend or shorten the serum half-life of Fc-containing therapeutics, which can impact the efficacy of the drug. It includes recommendations on the selection of biosensors, assay optimization, data collection, curve fitting, and methods for result analysis. [Contents (partial)] ■ Introduction ■ Octet platform for FcRn-antibody interaction analysis ■ Selection of biosensors and assay direction ■ Assay optimization ■ Data analysis ■ Intra-assay and inter-assay precision *For more details, please download the PDF or feel free to contact us.

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[Speaker] Yuzo Yamaguchi, Director, Mineral Division, Manufacturing Industries Bureau, Ministry of Economy, Trade and Industry [Key Lecture Content] I will explain the current situation regarding important minerals such as rare earths, which are essential for industrial activities, and the efforts being made to ensure stable supply. [Lecture Items] 1. Ensuring stable supply of important minerals such as rare earths 2. Q&A / Business card exchange

We would like to inform you that our company will be exhibiting at the 12th Liver and Diabetes/Metabolism Research Conference.

Sekiguchi Iron Works Co., Ltd. will be exhibiting at the 'AGTS Agricultural Exhibition in Aichi' held at the Aichi International Exhibition Center. This is an exhibition related to agriculture and livestock. Recently, the industry faces many challenges such as the disposal of agricultural waste, rising heavy oil prices, and regulations on open burning. Our incinerators will solve these problems. Both government officials and individuals are very welcome! We will be exhibiting in both outdoor and indoor booths. Please come visit us!

Our company will be exhibiting at the Kyushu and East Asia International Logistics Comprehensive Exhibition "INNOVATION EXPO 2026" held at Marine Messe Fukuoka. The present and future of logistics will converge in Fukuoka. A diverse range of products and services will be showcased, including transportation, sorting, picking, industrial vehicles, transport vehicles, trucks, pallets, containers, storage equipment, 3PL, consulting, carriers, packaging, logistics business support, and logistics base and facility development. We will provide valuable consultation and business negotiation opportunities for purchasing and procurement departments of logistics centers and companies in the Chubu region and surrounding areas, as well as for all those involved in logistics and supply chain across various industries. Visitors will have the opportunity to directly experience advanced logistics equipment, technologies, and systems, contributing to solving regional challenges. We sincerely look forward to your visit.

We will be exhibiting at the 26th Annual Meeting of the Japanese Society for Protein Science, which will be held from June 17 (Wednesday) to June 19 (Friday), 2026, at the Tottori Cultural Center in Tottori City, Tottori Prefecture. At this meeting, we will showcase the BLI biomolecular interaction analysis system, Octet R8e, and introduce the latest application examples and usage methods. Experience the easy setup and shutdown of Octet BLI, its high throughput, and the analysis of measurement data. We also welcome inquiries about measurement workflows, so please stop by our booth (Booth Number: Lobby [8]). Additionally, we will have a lecture by Professor Katsumi Maenaka from Hokkaido University Graduate School of Pharmaceutical Sciences on the forefront of compound screening and antibody binding analysis. [Exhibition Booth] Lobby 8 [Luncheon Seminar] Date: June 17, 2026 (Wednesday) 11:25-12:15 Theme: The Forefront of Compound Screening and Antibody Binding Analysis Location: Venue C (Small Hall) We look forward to your visit!