BIO JAPAN 2016

Technical Overview
This technology enables the three-dimensional imaging of the localization distribution of small molecular compounds whose properties change when labeled with fluorescent dyes, by identifying molecular structures through induced Raman scattering under a microscope. Unlike commercially available Raman microscopes, this system detects high-intensity induced Raman scattering light, which is advantageous for depth-direction tomography. To make the coherent Raman microscope operable by non-specialist users, the light source has been integrated, and it has been commercialized as an all-in-one measurement device.
Highlights of the Exhibition
The actual device will be used to demonstrate the measurement procedures for inhalation anesthetic molecules, steroid molecules, amino acids and amino acid derivatives, vitamins, and other samples, presented through video explanations. The panel will explain a successful case where the cornea of a mouse eye was immersed in a taurine solution, which is also included in eye drops, and the concentration distribution within the cornea was detected.
Expected Applications
- Non-destructive measurement of drug penetration into the skin and other tissues
- Measurement of the distribution of drug molecules within cells
- Tracking changes in molecular composition due to metabolism and other factors

Date and time | Wednesday, Oct 12, 2016 ~ Friday, Oct 14, 2016 10:00 AM ~ 05:00 PM |
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Capital | Pacifico Yokohama Hall C, D A-14 Inside the Japan Agency for Medical Research and Development (AMED) booth |
Entry fee | Charge Free with pre-registration. |
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