[Announcement of Webinar] Agilent Pharma / Biopharma Virtual Summit 2021

Agilent dissolution tester online UV system

The Cary 60 spectrophotometer, when combined with a pump in an online UV system, along with the sampling station 850-DS, allows for filter filtration and simultaneous sampling into test tubes or HPLC vials after filtration. **Evaluation Method for Drugs in Dissolution Testing Using Fiber Optics** Using fiber optics enables direct quantification of drugs within the vessel without the need for sampling. For example, when using fiber optics in dissolution testing for the evaluation of crystallization suppression of solid dispersions aimed at improving solubility, detailed dissolution profiles can be obtained through measurements at short intervals, as no sampling is required.

• UV/visible spectrophotometer

JP17 Bureau Reference Information: Mechanical Calibration Correspondence for Dissolution Test Apparatus

The 280-DS MQS measures the parameters of mechanical calibration of dissolution testers with high precision. Measurement is done hands-free thanks to sensor technology, taking only about 30 minutes per unit. It complies with 21 CFR Part 11. ★ Mechanical calibration has been included as reference information in the 17th edition revision. "To aim for reduced variability in test results through mechanical calibration, it is recommended to apply this reference information." (From the 17th Japanese Pharmacopoeia revision "Standard Methods for Mechanical Calibration of Dissolution Testers")

• Dissolution Tester

Corresponds to the Japanese Pharmacopoeia, USP, and EP3. The design minimizes mechanical variation factors of the device using vessels that reduce the deviation of the container's centering.

The dissolution tester 708-DS features one-touch centering with the TruAlign vessel, and its design minimizes the risk of misalignment after installation, reducing the risk of failure during mechanical calibration. It supports Japanese language, has a two-piece paddle, and significantly improves basic operability with an expanded space between the drive unit and the vessel plate. It accommodates a wide range of dosage forms for dissolution testing, including tablets, capsules, rotating cylinders, and the paddle-over-disk method.

• Dissolution Tester

It automatically performs sample suction, filtration, and collection from the dissolution tester.

■Efficiency Automation enables easy and quick sampling. It eliminates the labor involved in dissolution testing and prevents variations in sampling volume and position that would be difficult to manage manually. All functions, including the pump, filter (optional), and sampler, are integrated into a device just 39 cm wide. One filter plate used for sample filtration contains the equivalent of eight 0.45 μm filters. ■Flexibility In addition to the standard pump function, you can select filter functions according to your needs. Sampling can accommodate test tubes, HPLC vials, and well plates. ■Accuracy The rotary piston syringe pump ensures precise sampling of the specified amount at designated sampling points. Uniformity The color touch panel of the 850-DS allows for input of the dissolution test program. ■Test Results Test data can be printed using the built-in printer.

• Dissolution Tester

Management of test data, data integrity, dissolution testing software!

Since 2015, guidance on data integrity (DI) has been issued by the MHRA (UK Medicines and Healthcare products Regulatory Agency), WHO, FDA, and PIC/S, and its importance has been increasing in recent years. DI is defined as "the completeness, consistency, and accuracy of data. Data that is complete, consistent, and accurate is recorded with attributes of traceability, legibility, and contemporaneity, and is either original data or a true copy, and is accurate." It also ensures that pharmaceuticals meet the required quality standards. DWS is the optimal software for ensuring data integrity in dissolution testing. It supports access management, data tampering prevention, and backup, allowing for the management and control of dissolution testers and their peripheral devices with just this one software, making complex methods and data management easier to handle.

• Dissolution Tester

We will be exhibiting at the J AGRI (J Agri) / Agricultural Materials EXPO held at Gran Messe Kumamoto from May 22 (Wednesday) to May 24 (Friday), 2024. 【Booth Number】: B1-43 Outdoor Exhibition Area Japan's largest comprehensive exhibition for agriculture and livestock, Agricultural WEEK, will be renamed J AGRI starting in 2024. This is a place where you can actually see, touch, and compare products. At our booth, we will showcase our lightweight resin flooring boards "JULIGHT / SUPER JULIGHT / RAKURAKUBAN" along with new products. Starting with the agricultural-specific flooring board "RAKURAKUBAN," which can be easily laid in various scenes such as around greenhouses, agricultural work sites, temporary parking lots, for the movement of agricultural machinery and light trucks, and for protecting truck beds, there are various ways to use the lightweight resin flooring boards "JULIGHT / SUPER JULIGHT series." We offer a variety of sizes and protrusion shapes tailored to customer needs, and they are lightweight enough to be carried by hand, with excellent impact resistance, as well as superior water resistance, weather resistance, and durability, providing outstanding features not found in plywood or steel plates. We sincerely look forward to your visit.

Dear Sir or Madam, We hope this message finds you well and that your company continues to prosper. FUKUDA will be exhibiting at the 28th INTERPHEX Week Tokyo. At the exhibition, we will be showcasing 100% inspection equipment compliant with Container Closure Integrity Testing (CCIT) standards, as well as sampling inspection machines. We sincerely invite you to visit our booth at this opportunity and would greatly appreciate your attendance despite your busy schedule. Yours sincerely, [Dates] May 20 (Wed) - 22 (Fri), 2026 10:00-17:00 (JST) [Venue] Makuhari Messe, Japan 8 Hall Booth No. 41 - 36

Dear Sir or Madam, We hope this message finds you well and that your company continues to prosper. FUKUDA will be exhibiting at the AUTOMOTIVE ENGINEERING EXPOSITION 2026 YOKOHAMA. At this exhibition, we will be showcasing testing equipment such as Air Leak Tester for EV and Equipment Mounted Type Hydrogen Leak Detector. We sincerely hope you will take this opportunity to visit us. Yours sincerely, [Official Site] https://aee.expo-info.jsae.or.jp/en/yokohama/ [DATES] Wednesday, May 27, through Friday, May 29, 2026 10:00 a.m. - 5:00 p.m. [VENUE] PACIFICO Yokohama, Exhibition Hall, Booth No. ２７４ ※Online Exposition Website：Tuesday, May 19, through Tuesday, June 9, 2026

[Speaker] Toshio Fujimura, Ph.D. (Engineering) Representative, Touson Automotive Strategy Research Institute Automotive and Environmental Technology Strategy Analyst Visiting Professor, Aichi Institute of Technology [Former Toyota Motor Corporation] [Lecture Topics] <Chapter 1> Urgent Issue: CO2 Reduction Cannot Wait! <Chapter 2> Achieving a 48% Reduction in CO2 by 2030 Compared to 2019 is Impossible Without Carbon Neutrality in Fuels as Well as Electricity <Chapter 3> Technical Challenges in Electrification <Chapter 4> Pathways to Achieve a 48% Reduction in CO2 Emissions from Owned Vehicles by 2030 <Chapter 5> The Intentions Behind Electrification Strategies of Various Governments (Mainly in Europe, the U.S., and China) <Chapter 6> Electrification Strategies of Major Global Automakers and Sales Trends in Different Regions: Which Manufacturers Will Survive by 2030? <Chapter 7> Conclusion

[Speaker] Masayuki Sawada, Director of Sawada Masayuki Engineering Office [Lecture Topics] 1. The battle in Ukraine is the first large-scale drone war in history. 2. The battle in Iran also sees drones shifting the paradigm of strategy and tactics. 3. Efforts by major European countries (producing drones in Ukraine and collaborating with Ukrainian drone manufacturers). 4. Efforts by the United States (providing intercept drones and other support to Ukraine). 5. Efforts by Taiwan (producing drones in collaboration with U.S. manufacturers that have combat experience in Ukraine). 6. Efforts by Japan's Ministry of Defense (establishing a multi-layered coastal defense system using drones [SHIELD]). 7. Efforts by Japan's Terra Drone Corporation (collaborating with Ukrainian drone manufacturers). 8. Q&A / Business card exchange.