[Announcement of Webinar] Agilent Pharma / Biopharma Virtual Summit 2021

Agilent dissolution tester online UV system

The Cary 60 spectrophotometer, when combined with a pump in an online UV system, along with the sampling station 850-DS, allows for filter filtration and simultaneous sampling into test tubes or HPLC vials after filtration. **Evaluation Method for Drugs in Dissolution Testing Using Fiber Optics** Using fiber optics enables direct quantification of drugs within the vessel without the need for sampling. For example, when using fiber optics in dissolution testing for the evaluation of crystallization suppression of solid dispersions aimed at improving solubility, detailed dissolution profiles can be obtained through measurements at short intervals, as no sampling is required.

• UV/visible spectrophotometer

JP17 Bureau Reference Information: Mechanical Calibration Correspondence for Dissolution Test Apparatus

The 280-DS MQS measures the parameters of mechanical calibration of dissolution testers with high precision. Measurement is done hands-free thanks to sensor technology, taking only about 30 minutes per unit. It complies with 21 CFR Part 11. ★ Mechanical calibration has been included as reference information in the 17th edition revision. "To aim for reduced variability in test results through mechanical calibration, it is recommended to apply this reference information." (From the 17th Japanese Pharmacopoeia revision "Standard Methods for Mechanical Calibration of Dissolution Testers")

• Dissolution Tester

Corresponds to the Japanese Pharmacopoeia, USP, and EP3. The design minimizes mechanical variation factors of the device using vessels that reduce the deviation of the container's centering.

The dissolution tester 708-DS features one-touch centering with the TruAlign vessel, and its design minimizes the risk of misalignment after installation, reducing the risk of failure during mechanical calibration. It supports Japanese language, has a two-piece paddle, and significantly improves basic operability with an expanded space between the drive unit and the vessel plate. It accommodates a wide range of dosage forms for dissolution testing, including tablets, capsules, rotating cylinders, and the paddle-over-disk method.

• Dissolution Tester

It automatically performs sample suction, filtration, and collection from the dissolution tester.

■Efficiency Automation enables easy and quick sampling. It eliminates the labor involved in dissolution testing and prevents variations in sampling volume and position that would be difficult to manage manually. All functions, including the pump, filter (optional), and sampler, are integrated into a device just 39 cm wide. One filter plate used for sample filtration contains the equivalent of eight 0.45 μm filters. ■Flexibility In addition to the standard pump function, you can select filter functions according to your needs. Sampling can accommodate test tubes, HPLC vials, and well plates. ■Accuracy The rotary piston syringe pump ensures precise sampling of the specified amount at designated sampling points. Uniformity The color touch panel of the 850-DS allows for input of the dissolution test program. ■Test Results Test data can be printed using the built-in printer.

• Dissolution Tester

Management of test data, data integrity, dissolution testing software!

Since 2015, guidance on data integrity (DI) has been issued by the MHRA (UK Medicines and Healthcare products Regulatory Agency), WHO, FDA, and PIC/S, and its importance has been increasing in recent years. DI is defined as "the completeness, consistency, and accuracy of data. Data that is complete, consistent, and accurate is recorded with attributes of traceability, legibility, and contemporaneity, and is either original data or a true copy, and is accurate." It also ensures that pharmaceuticals meet the required quality standards. DWS is the optimal software for ensuring data integrity in dissolution testing. It supports access management, data tampering prevention, and backup, allowing for the management and control of dissolution testers and their peripheral devices with just this one software, making complex methods and data management easier to handle.

• Dissolution Tester

We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will introduce a number of products, including our new product, the Pillow Packaging Full Air Tightness Inspection Machine MSQ-2003. We sincerely apologize for the inconvenience during your busy schedule, but we would like to invite you to visit us at this opportunity. 【 Exhibition Name 】 JAPAN PACK 2025 Japan Packaging Industry Exhibition https://www.japanpack.jp/ 【 Dates 】 October 7 (Tuesday) to October 10 (Friday), 2025 *4 days 10:00 AM to 5:00 PM 【 Venue / Booth Number 】 Tokyo Big Sight / East Hall 8, Booth 8-505

Our company will be exhibiting at "POWTEX Powder Technology Exhibition Osaka 2025" held at Intex Osaka. During the event, we will showcase various products. We invite all related parties to come and visit us. 【Suppliers】 ・Hielscher

Method for determining inspection standards, standard values, and safety factors based on economic risks Practical introduction to a method of consideration that prevents profit and loss without relying on statistical distribution (loss function) 【Half-Day Intensive Seminar】 －－－－－－－－－－－－－－－－－－－－－－－－－－－－－ https://www.thplan.com/seminar/110739/ ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ We will inform you about upcoming technical seminars with discounted participation fees. If you would like to apply for each seminar with a discount, please contact ikuma.fukui@wmjplab.com. * The discount on participation fees is available to anyone. * However, we do not accept participation from technical consultants or instructors. * If you wish to have an in-house training session for the same seminar, please contact me directly. ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━

This time, Antecs will be exhibiting at the "28th Machine Element Technology Exhibition - Kansai (Osaka)" held at Intex Osaka. We will showcase our lightweight and compact swivel turntable "Raku-kka," which we designed and manufactured in-house, as well as the "Transparent Clear Model," which is the same size as an actual small swivel bearing and further visualizes its internal structure. When you visit, please feel free to "touch" and "rotate" them! We look forward to seeing you.

In aerospace, automotive, and other fields, rapid advancements in material development and manufacturing technology are being made to achieve further weight reduction aimed at improving fuel efficiency and reducing carbon dioxide emissions. This seminar will provide an easy-to-understand explanation for beginners about the development trends of new materials and various lightweight technologies, including additive manufacturing (AM) and manufacturing techniques, as well as product case studies from advanced companies energetically working towards ultra-lightweight solutions using lightweight materials such as carbon fiber, magnesium, and aluminum. We will discuss complex shapes and integrated structures that are impossible with conventional processing methods, as well as lattice/honeycomb structures, porous structures, and topology optimization through 3D printing, incorporating both success and failure stories. A recent topic of interest is magnesium alloys, which require caution for practical use due to their flammability. However, Tobata Seisakusho has newly developed a flame-retardant magnesium alloy and is currently working on layered manufacturing using metal 3D printers. We will introduce a case study of a prototype created with a lattice structure. Lightweighting of components, which is gaining attention as a next-generation candidate that can significantly differentiate itself from conventional and competitor parts, is an urgent and critical issue, with intense technological development competition occurring both domestically and internationally. Development along the lines of existing technologies is not expected. We encourage you to take on the challenge.