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  3. プロテインシンプルジャパン
  4. Targeted degradation of enhancer lysine acetyltransferases CBP and p300: Free Webinar
SEMINAR_EVENT
  • Mar 10, 2021
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Mar 10, 2021

Targeted degradation of enhancer lysine acetyltransferases CBP and p300: Free Webinar

プロテインシンプルジャパン プロテインシンプルジャパン
Chromatin regulators CBP and p300 maintain gene expression programs through lysine acetylation of chromatin and transcription regulators, as well as through scaffolding functions mediated by several protein-protein interaction domains. Using cell activity assays, including in silico modeling and capillary-based immunodetection assays (ProteinSimple, WES), we developed a chemical degrader for p300/CBP, dCBP-1. We found that dCBP-1 is highly effective at killing multiple myeloma cells and can disable enhancers that promote the expression of the MYC oncogene. As an efficient degrader of this unique class of chromatin regulators, dCBP-1 will serve as a useful tool for understanding p300/CBP activity at enhancers in both normal and diseased cells.
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Date and time Wednesday, Mar 24, 2021
01:00 AM ~ 02:00 AM
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Entry fee Free
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Fully Automatic Western "Jess"

Equipped with multiplex two-color fluorescence and automatic protein normalization function!

"Jess" is a solution that automates traditional Western blotting protein separation and immunoassay detection, eliminating labor-intensive steps that are prone to errors and mistakes. In addition to the features of Wes, it is a small high-end model equipped with multiplex two-color fluorescence and automatic protein normalization capabilities. It is a new product with fluorescence functionality. <New Feature: Capillary Reprobing> By combining the newly introduced RePlex Module with traditional reagent kits, it becomes usable! You can view examples such as "Assays for two target proteins and total protein normalization" and "Examples of signal intensity standardization based on total protein amount" from the "PDF Download." Please take a look. 【Features】 ■ Measurement with minimal sample volume (1/5 to 1/10 of the traditional amount) ■ Complete quantification, high reproducibility, and high sensitivity ■ Overwhelming processing capacity (short measurement time starting from 3 hours) ■ Elimination of human error *For more details, please refer to the PDF materials or feel free to contact us.

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Protein-related Products Product Catalog

Currently offering the 'Protein-Related Products Product Catalog'! Includes alternatives for Western blotting and total protein analysis!

This is the product catalog of Protein Simple Japan, Inc., a member of the division based on protein-related products from Bio-Techne Corporation. It features products such as the fully automated Simple Western system "Wes," which surpasses the Western blot method in every aspect, as well as "Milo," which allows for protein expression analysis at the single-cell level, and the "Total Protein Assay Kit." [Contents] ■ New alternatives to Western blot ■ Western analysis at the single-cell level ■ Revolutionizing multiplex assays ■ Biopharmaceutical development tools *For more details, please download the PDF or feel free to contact us.

  • Other physicochemical equipment

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Webinar Announcement: Automating RNA-seq Library Prep: From Rare Cells scRNA-seq to High-Throughput Bulk RNA-seq

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  • SEMINAR_EVENT

In this webinar by SPT Labtech and Alithea Genomics, we will introduce practical methods to eliminate bottlenecks in library preparation, from single-cell RNA-seq to bulk RNA-seq. - Streamlining rare cell workflows: By combining FLASH-seq and firefly, we can complete full-length scRNA-seq library preparation from low-input or FACS-sorted samples in one day. - Scaling up bulk RNA-seq: Achieve high-throughput screening compatible with 96/384 well plates using extraction-free, plate-based solutions like Total DRUG-seq. - Accelerating the process from sample to data: We will provide practical tips for reducing manual work and smoothly integrating automation. - Case studies: We will demonstrate the effectiveness through case studies and real data in various applications of RNA-seq.

Nov 04, 2025

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Webinar Announcement: Bitten by Mosquito: The Big Impact of Going Small

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Join our expert webinar to discover how SPT Labtech's mosquito liquid handler is transforming the approach to assay miniaturization. - Smartly scaling up workflows at the nanoliter scale: Learn how to optimize existing genomics, screening, and chemistry protocols for ultra-low volumes, and the new possibilities that arise from this. - Considering value beyond cost reduction: Miniaturization enables innovative applications such as single-cell omics, workflows for direct processing from cells, and optimization of parallel reactions. Real case studies: We will present examples of academic and industrial labs that have successfully scaled up their research using mosquito.

Nov 04, 2025

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【11/29・30 | Nagoya】Mediceo Medical Fair 2025 in Tokai

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Our company will be exhibiting equipment at the "Mediseo Medical Fair 2025 in Tokai." We sincerely look forward to your visit.

Nov 04, 2025

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Continuously increase high LTV "fan customers"! AI marketing implementation seminar to improve effectiveness and operations.

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  • SEMINAR_EVENT

As you advance the utilization of AI, you may face challenges such as "while certain results are achieved in validation, they do not translate into operational use," "the model has been created, but it cannot be implemented into measures, making ROI difficult to explain," and "collecting and preprocessing the data for utilization takes time." This presentation will explain a method to streamline data preparation with no-code solutions, generate key features that are essential for AI accuracy, train them using the latest algorithms, and automate the implementation up to actual marketing measures.

Nov 04, 2025

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Notice of Participation in the Surface Modification Exhibition 2025 from December 3 (Wednesday) to December 5 (Friday), 2025.

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  • SEMINAR_EVENT

Nihon Jet-On Co., Ltd. will be exhibiting at the "Surface Modification Exhibition 2025" held at Tokyo Big Sight. This exhibition is a comprehensive showcase of surface treatment technologies, introducing various techniques that achieve improved wear resistance and extended lifespan through processes such as heat treatment and plating, thereby enhancing added value and functionality. We sincerely look forward to your visit.

Nov 04, 2025

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