Report on the 9th Cosmetics Industry Technology Exhibition CITE JAPAN 2019

Tasmanian High Purity Whitening Fucoidan Polyphenol (Hibama Extract) Maritech Bright

MARINOVA is a biotechnology company established in 2003 in Tasmania, Australia. It is the manufacturer of the world's only high-purity organic fucoidan extract derived from brown algae, using its unique green chemistry technology. The company's product, MARITECH BRIGHT, is made from sustainable raw materials. =Sustainable Manufacturing Process= 1) Sustainable Sourcing: Wild seaweed is sourced from four regions around the world, employing harvesting methods that consider regeneration. 2) Zero Waste: Renewable energy (zero CO2 emissions) is used, and waste is utilized in agriculture. 3) Extraction with water, with 50% being reused. =About the Product= - Ingredients: Contains ≥90% fucoidan and polyphenols - Efficacy: 1) Anti-aging functions - Improves skin radiance - Reduces wrinkle depth - Stimulates expression of anti-aging gene SIRT1 - Inhibits glycation (50%) - Suppresses collagenase, tyrosinase, and elastase by up to 99% 2) Whitening functions - Improves pigmentation (20%) 3) Antioxidant functions - Removes free radicals - Against UVA/B: Suppresses erythema and TEWL caused by irradiation - Oxygen radical absorption capacity (twice that of VC)

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

Sodium hyaluronate derivative, retinol derivative, anti-wrinkle, elasticity improvement, pore tightening, acne improvement.

HyRetin is a product that introduces retinoids to low molecular weight sodium hyaluronate, enhancing the stability and skin permeability of retinoic acid. =In Vitro= - Anti-inflammatory effects: IL-8: -15%, IL-6: -40% - Promotion of collagen type 1 production: +40% - Promotion of fibronectin production: 1.4 times (vs control) =In Vivo= - Dermal density: +10% improvement - Number of dermal papilla cells: +48% - Improvement in skin elasticity: -34% (recovery time) - Reduction in wrinkle depth: -36% - Skin radiance: +43% - Skin moisture level: +7% - Erythema suppression effect: -6% - Sebum reduction effect: -36% - Pore size: -25% - Anti-acne effect: size: -50%, number: -68.75% and more.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients
• Other medical supplies and cosmetic manufacturing materials

Cosmetic ingredients, Tasmanian origin, high purity, anti-aging fucoidan (wakame extract), anti-pollution, virus protection, UV damage recovery.

- Ingredients: Contains Fucoidan ≧ 85% - Efficacy: 1) Anti-aging function - Wrinkle depth: -9% - Stimulation of anti-aging gene SIRT1 expression (+28%) - Glycation inhibition effect (-50%) - Inhibition of collagenase and elastase by up to 99% 2) Protection effect - Suppression of erythema after UV exposure by 45% - Antiviral effect (multiple including herpes simplex) 3) Moisturizing and smoothing - Increase in moisture by 30% after UV exposure - Increase in stimulation of skin cell expression after UV exposure - Inhibition of myeloperoxidase by up to 99%

• others
• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients

Fukuda Co., Ltd. has been pursuing leak detection for 60 years and is committed to advancing the future of leak testing. 【 Supporting Various Leak Tests: Air Leak Test / Gas Leak Test (Hydrogen Gas, Helium Gas) 】 We develop, manufacture, and sell leak testing equipment to inspect airtightness and sealing properties. We will propose the appropriate testers and devices for each inspection target. 【 Target Industries and Examples of Inspection Targets 】 - Automotive Industry: Engines, FC components, valves and piping, various parts - Electronic Components Industry: Smartphones, keyless switches, various small sensors - Pharmaceuticals / Food / Cosmetics Industry: Bottle containers, syringes, vials, eye drop containers, pillow packaging, PTP packaging We will propose the most suitable leak testers for each industry. 【 ISO Certification 】JIS Q 9001:2015 (ISO 9001:2015)

Hotron, which manufactures and sells sensors, provides bed exit sensors for hospitals, nursing, and care facilities. Hotron offers easy-to-understand video guidance on how to use the bed exit sensors wirelessly and how to set up device connections! ▼ Video Manual (YouTube) https://www.youtube.com/playlist?list=PLNVA4mTrZDqtJa6MfFRZQxwtfCSnAfxVy 【Bed Exit Sensors】 ○ Non-contact infrared sensor, simply place it - Pole-kun HB-H1 ○ Mat sensor, foldable thin mat - Mat-kun HB-UST ○ Body movement call - Ugo-kun HB-TV3 ○ Body movement call for wheelchairs - Ayumi-chan HB-WTV3 【Options】 ○ Nurse call linked wireless set - Wireless set (transmitter/receiver) HB-RS/HB-RJ ◎ For more information about the products, please contact us or download the catalog.

Fukuda's new flagship model. - Masterless type (FLA-0200 series) - General type (FLA-0201 series) Two models of air leak testers. With the mastering correction function, high-precision measurements can be achieved in a short time. Please take a look at the catalog.

● This is a leak testing device for small electronic components that does not use fluorinated inert liquids (PFAS-free). ● There is no longer a need for unstable visual confirmation through liquid immersion testing. It adopts a quantitative testing method that allows for stable pressure leak testing. ● It is a tabletop leak testing device specifically for gross leaks, with accuracy equal to or greater than that of liquid immersion testing. ● The detectable range is approximately 1×10⁻² Pa·m³/s to 1×10⁻⁶ Pa·m³/s (varies depending on the target product). ● It is suitable for sealed structures ranging from a few millimeters to a maximum of 80 × 70 mm. Please feel free to contact us for more information!

The "Mechanical Stitching Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact on the base material. Repairs can be carried out even in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.