Sodium hyaluronate derivative, retinol derivative, anti-wrinkle, elasticity improvement, pore tightening, acne improvement.
HyRetin is a product that introduces retinoids to low molecular weight sodium hyaluronate, enhancing the stability and skin permeability of retinoic acid. =In Vitro= - Anti-inflammatory effects: IL-8: -15%, IL-6: -40% - Promotion of collagen type 1 production: +40% - Promotion of fibronectin production: 1.4 times (vs control) =In Vivo= - Dermal density: +10% improvement - Number of dermal papilla cells: +48% - Improvement in skin elasticity: -34% (recovery time) - Reduction in wrinkle depth: -36% - Skin radiance: +43% - Skin moisture level: +7% - Erythema suppression effect: -6% - Sebum reduction effect: -36% - Pore size: -25% - Anti-acne effect: size: -50%, number: -68.75% and more.
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basic information
Contipro is a biotechnology company located in the Czech Republic. It is a global manufacturer that has been supplying various active ingredients, primarily sodium hyaluronate, to the pharmaceutical and cosmetic fields for about 30 years. The products are categorized into three types: sodium hyaluronate, natural polysaccharides, and peptides. HyRetin is a product that obtained its cosmetic ingredient name in 2021.
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Properties: Water-soluble powder Recommended usage amount: 0.1 - 0.01% DAY CREAMS: 0.01 - 0.05% NIGHT CREAMS: 0.02 - 0.05% LOTIONS: 0.01 - 0.05% EYE CREAMS: 0.01 - 0.02% SERUMS: 0.05 - 0.10% MASKS: 0.01 - 0.10%
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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.