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Presentation of verification materials exploring the application to the evaluation of cell quality and experimental systems!

This document is a verification report that measures parameters in the culture supernatant during the maintenance culture of iPS cells and the differentiation induction process from iPS cells to dopamine-producing neural progenitor cells, exploring applications for evaluating cell quality and experimental systems. In addition to the experimental content and the composition of reagents and media, it discusses differentiation induction and maintenance culture. 【Contents】 ■ Purpose ■ Experimental Content ■ Reagents and Media Composition - Differentiation induction into neural progenitor cells - iPS cell culture ■ Discussion *For more details, please refer to the PDF document or feel free to contact us.

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Accelerating the development of the COVID-19 vaccine - Rapid simultaneous measurement of multiple items with trace samples using the automatic analysis device for cell culture environments, FLEX2.

To prevent the spread of the novel coronavirus (COVID-19), the urgent development of vaccines is required. It is said that managing the culture environment is crucial in the process of vaccine research and development involving host cell cultures. The "BioProfile" series of cell culture environment analysis devices from Nova Biomedical is widely adopted by major pharmaceutical companies and institutions in Japan and around the world for managing culture environments in vaccine research, development, and manufacturing processes. At Nova Biomedical, we hope to contribute, albeit modestly, to the development of COVID-19 vaccines by offering flexible purchasing programs tailored to your budget. For more details, please contact us through the inquiry form, and we will respond promptly. We also have materials available for cell culture analysis using our devices. 【Features】 - Monitoring the progress of cell culture - Quantification of key components in the culture medium - Early detection of abnormalities in the culture environment through regular monitoring - Capability to measure multiple items with one device, significantly reducing measurement time by consolidating the functions of multiple devices into one - Numerical backing for the timing of medium changes - Maintenance-free and sensor card-based, reducing the workload for researchers on equipment maintenance

• Other physicochemical equipment

An automatic analysis device for cell culture environments that achieves "shortened measurement time" and "significant reduction in sample volume"! All 16 items can be measured with just a small amount of sample.

The "BioProfile FLEX2" is an analytical device that utilizes micro-sensor technology. This technology allows the "BioProfile FLEX2" to achieve "reduced maintenance related to electrodes," "shortened measurement time," and "significantly reduced sample volume," making it an automatic analysis device for cell culture environments. It can measure all 16 parameters with a minimal sample volume, completing all 16 measurements in just 4 minutes and 30 seconds, or 2 minutes for individual modules. 【Features】 ■ Monitoring the progress of cell culture ■ Quantification of key components in the culture medium ■ Early detection of abnormalities through regular monitoring ■ Capability to measure multiple parameters with one device, consolidating the functions of multiple devices into one ■ Numerical backing for the timing of medium exchange *For more details, please request documentation or view the PDF data available for download.

• Other physicochemical equipment

Presentation of verification materials for iPS cell culture: Simultaneous measurement and analysis of up to 16 items in 4 minutes and 30 seconds! Strong support for improving culture efficiency.

There is data indicating that "an appropriate culture medium environment correlates with an increase in cell numbers," which necessitates the creation and adjustment of an appropriate culture medium environment to promote efficient cell culture. Are you unable to execute this due to the "time required for measurement and analysis" being a bottleneck? The cell culture environment automatic analysis device 'BioProfile FLEX2' can analyze the components of cell culture media for up to 16 items in just 4.5 minutes. It allows for rapid quantification of culture conditions such as metabolism, proliferation, and differentiation, contributing to the establishment of a culture environment aimed at mass production. ★ We are currently offering materials that investigate the correlation between changes in medium components and cell numbers in iPS cell culture. 【Features】 ■ Simultaneous analysis of up to 16 items ■ Rapid measurement time: as short as 2 minutes, up to 4 minutes and 30 seconds (depending on measurement items) ■ Capable of measuring consumption and production rates of major metabolites ■ Compatible with multiple shapes of sample containers ■ Equipped with an auto-sampling function for continuous measurement of samples *For more details, please refer to the materials available for download in PDF format.

• Other measurement, recording and measuring instruments
• Analytical Equipment and Devices

[Speaker] Jun Ishikawa, Professor at the Graduate School of Business Administration, Rikkyo University, and Vice President of Rikkyo University [Key Lecture Content] This lecture will provide a clear explanation of the most effective leadership in the VUCA era, focusing on shared leadership based on the latest research. Specifically, it will discuss how everyone can exhibit effective leadership to improve workplace and team outcomes, and how anyone can develop effective leadership skills through training. Additionally, it will explain what is necessary to foster shared leadership in workplaces and teams from both individual and organizational perspectives. To continue achieving results in the VUCA era, let’s challenge traditional views of leadership and explore new leadership concepts. [Lecture Items] 1. Characteristics of the VUCA Era 2. What is Shared Leadership? 3. Effects of Shared Leadership 4. Effectiveness of Personal Leadership Theories 5. How to Foster Shared Leadership in Workplaces and Teams 6. Q&A *This seminar will be held via Zoom meeting.*

[Speaker] PwC Advisory LLC Senior Manager Toshiya Nakamura [Key Lecture Content] The expected roles of smart meters (AMI) and DER (Distributed Energy Resources) in power systems are increasing both domestically and internationally. The DISTRIBUTECH conference, one of North America's largest exhibitions and conferences for transmission, distribution, and energy-related technologies, will be held in early February 2026 in San Diego, North America. Numerous power companies and manufacturers introduced the latest trends regarding the next-generation smart meter systems AMI 2.0 and the utilization of DER. In this lecture, I will share the latest trends in the utilization of smart meters and DER in the decentralization of power systems gained through participation in DISTRIBUTECH. [Lecture Items] 1. Overview of DISTRIBUTECH 2. Latest trends in AMI 2.0 3. Latest trends in DER utilization 4. Considerations for the utilization of smart meters and DER 5. Q&A / Business card exchange

[Speaker] Mr. Li Qiangfu, Senior Researcher, Planning and Research Department, Fourin Inc. [Lecture Topics] 1. Tesla Master Plan: Progress of Existing and New Businesses 2. Strategy as a Technology Trendsetter 3. Initiatives in Purchasing and Supply Chain 4. Efforts as an IT Service Platform Provider 5. Competition with Chinese Companies and Strategies to Differentiate 6. Q&A / Business Card Exchange

The goal is to understand the roles and functions of lithium-ion batteries and protection ICs, learn the basics of lithium-ion batteries and protection ICs, and provide fundamental information that can assist in the selection of protection ICs and subsequent circuit design. ● Target Participants - New employees and young designers at companies developing products related to lithium-ion batteries - Those who want to revisit the study of lithium-ion protection ICs - Those who are about to engage in circuit design related to lithium-ion batteries ● Agenda 1. What is a lithium-ion battery? 2. Types of lithium-ion secondary batteries (LIB) 3. Major manufacturers of LIB (Cell Maker) 4. LIB Supply Chain 5. Why is protection for LIB necessary? 6. Methods of LIB protection 7. Basic operation of protection circuits 8. Product lineup of Nisshinbo Micro Devices 9. Chip cross-section (process structure) 10. Rules for product names 11. Trends and considerations for secondary batteries (to be added in 2026) 12. Q&A

[Speaker] Naoto Ikeda, President and CEO of Granite Co., Ltd. / Automotive Economic Commentator [Key Lecture Content] In 2025, the extreme policies of various countries to "ban internal combustion engines by a certain year" were successively retracted, and the ambitious policy to convert all cars in the world to EVs has been shattered. However, the goal of "carbon neutrality by 2050" is still being upheld. As a result, the world has arrived at a "multi-pathway" approach. This framework allows everyone in the world, with different economic, infrastructural, and usage environments, to participate in CO2 reduction that suits their circumstances by intertwining various technologies. The most significant force expected within this framework is bioethanol. We invite you to participate in this opportunity to consider how the bioethanol technologies that the world is currently working on will change our future. [Lecture Items] 1. Reasons why EVs are not breaking through 2. Basic knowledge of carbon neutrality 3. What is bioethanol? 4. Japan's technology: "Toyota Yeast" 5. Specific strategies for dissemination: Drop-in 6. Challenges and solutions for bioethanol 7. Summary 8. Q&A / Business card exchange