Notice of participation in the "24th Interphex Week Tokyo" from July 13 (Wednesday) to July 15 (Friday).

Easy with 90-degree operation! Prevents over-tightening and damage! We solve concerns like "I'm worried if it's securely tightened..."

The "BQL400NB model" is a rapid-opening and closing type handle diaphragm valve from BioClean. While the standard handle version requires about 5 turns of operation (for DN50), the rapid-opening and closing handle allows for a very simple operation of just 【opening and closing by 90 degrees】. The position of the handle makes it clear to see the valve's open and close status even from a distance. Additionally, it has achieved a lighter and more compact design compared to conventional products. Please try the easy operation and stable sealing performance of the 90-degree rotating lever handle. 【We solve the following problems!】 ■ The opening and closing torque is excessive. → It can be reduced, greatly contributing to labor savings. ■ I want to check the open and close status from a distance. → The handle position clearly shows the valve's open and close status even from afar. ■ The valve is damaged due to over-tightening. → Only the minimum necessary operation is required. This prevents damage and extends lifespan. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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Many delivery achievements for pharmaceutical and food plants, as well as high-purity chemical solutions! It can completely block corrosive fluids.

At Nippon Diaphragm Valve, we handle "clamp-connected corrosion-resistant valves" with a body made of fluororesin (ETFE) lining. These valves are suitable for countermeasures against corrosive fluids in sanitary piping, gap corrosion due to chloride ions, and metal ion elution. With the diaphragm valve's features of "air tightness" + "corrosion resistance," they can completely shut off corrosive fluids. We have many achievements not only in pharmaceutical and food plants but also in high-purity chemical lines. 【Features】 ■ Body material: SUS316L ■ Lining material: ETFE ■ Connection method: Clamp joint (ISO2852) ■ Applicable nominal diameter: 25A to 65A (1S to 2.5S) *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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No short pipe section and minimal dead leg! A compact design sample collection valve.

The "Bio-Clean Diaphragm Valve" is a dedicated valve for sample collection. Since it does not use a cheese fitting, there is no short pipe section, resulting in a smaller dead leg. Additionally, its compact design and lightweight construction help reduce the load on the piping. It can be widely used for introducing and discharging split flow, merging (mixing liquids), cleaning water, and sterilizing steam. 【Features】 ■ Does not use a cheese fitting ■ No short pipe section, resulting in a smaller dead leg ■ Compact installation due to the integrated structure of the main pipe and body ■ Average weight reduction of 23% compared to conventional products ■ Reduced load on piping due to lightweight design *For more details, please refer to the documentation. Feel free to contact us with any inquiries.

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No adhesion of tablets or powder particles, excellent cleaning properties!

We handle "valves exclusively for the discharge of tablets and powder granules." With a shape and structure that minimizes tablet residue, we offer a "damper" for safe tablet discharge, and a "butterfly valve" designed for lightweight construction, making installation and removal easy. The main components are made of stainless steel and have a buff-polished finish, ensuring no adhesion of tablets or powder granules and excellent cleanability. 【Features】 <Damper> - Structure that does not crush tablets when opening the damper - Equipped with a stopper at the opening and closing position to securely maintain the position <Butterfly Valve> - Lightweight design allows for easy installation and removal from containers and piping - Adopts a clamp method for quick assembly and disassembly, making cleaning easy *For more details, please refer to the PDF materials or feel free to contact us. (The English version of the catalog can be downloaded from the catalog page of the special website below.)

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Aiming to create environmentally friendly valves... "The entire company is united in promoting the continuous reduction of environmental impact!" "ISO 14001 certification obtained!"

Japan Diavalve Co., Ltd. aims to be a sustainable company that balances environmental activities and economic activities amid the worsening global environmental issues. Recognizing the commitment to environmental conservation as one of the important pillars of its business activities, the company obtained ISO 14001 certification in 2008 and is working together as a whole company on environmental activities. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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A product series designed with a valve body structure that is compact and free of dead spaces (such as pockets and liquid pools)!

Features 1) This product is designed with a compact structure for the valve body, eliminating dead spaces (such as pockets and liquid traps). 2) Notable examples include a self-draining type that enhances liquid trap prevention, a sampling valve for fluid sample collection, a three-way valve that allows fluid switching and mixing with a single body, and a tank bottom valve that achieves high stirring efficiency and complete discharge without residue. 【Lineup (Excerpt)】 ■ Self-draining type ■ Sampling valve: P type ■ Three-way valve: K type ■ Tank bottom valve: T type *For more details, please refer to catalog pages 17 to 21 or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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An evolved version of the bio-clean diaphragm valve. The structure eliminates liquid pooling by positioning the valve shaft horizontally. A solution for dead space!

The self-draining type is a valve body that further enhances the liquid retention prevention effect of the Bio Clean diaphragm valve series. When this valve is installed on horizontal piping, it is designed to eliminate liquid retention by positioning the valve shaft horizontally. 【Specifications (excerpt)】 ■ Stainless steel body (Applicable nominal diameter (DN): 8 to 100) ■ Lined body (Applicable nominal diameter (DN): 15 to 50) ■ The surface finish classification of the body and diaphragm specifications follow standard specifications. ■ Various drive components for manual operation valves and pneumatic ON-OFF valves can be used interchangeably. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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Tanks from approximately 10L to 10,000L are acceptable! The opening and closing are done solely by the diaphragm, allowing for smooth discharge of the tank contents with almost no residue left.

【Features】 ● The structure is directly welded to the bottom of the tank, resulting in excellent stirring efficiency. ● There are no contact parts such as gland packing, stem, seat, or gasket; the opening and closing are done solely by the diaphragm, allowing for smooth discharge of the tank contents with minimal residue. Contamination caused by valve components is extremely low, and cleaning and sterilization can be easily and reliably performed. ● The applicable nominal diameters range from DN15 to 100 (4S), making it suitable for use with small containers of about 10 liters to medium tanks of about 10,000 liters. 【Specifications (Excerpt)】 ● Main body material: SUS316L ● Applicable nominal diameter (DN): 15 to 100 ● Operation method: Manual operation and pneumatic operation methods are both applicable. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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Diverting, merging, and the introduction and discharge of cleaning water and sterilizing steam are "applicable." The internal structure of the valve has no dead space, making it ideal for preventing liquid accumulation.

**Features** - It can be directly installed in the piping, is compact, and has a structure that prevents fluid residue in the valve. - It can be widely used for applications such as branching, merging (mixing liquids), introducing cleaning water, and discharging sterilization steam. **Specifications (Excerpt)** - Main body material: SUS316L - Applicable nominal diameter (DN): Standard combination of main pipe and valve: 15 to 50 (other ranges available as options) - Operation method: Both manual and pneumatic operation methods are applicable. *For more details, please refer to the catalog (P.20) or feel free to contact us. (An English version is available upon request!)*

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Manufacturing equipment for pharmaceuticals, food, semiconductors, etc.! A wide variety of sanitary specification valves available.

This document is a "comprehensive catalog" featuring sanitary specification valves suitable for manufacturing equipment in pharmaceuticals, food, semiconductors, and more. It includes the "Bio-Clean Diaphragm Valve Series," which maximizes the features of diaphragm valves, as well as sanitary butterfly valves for pharmaceutical containers. Customers can select valves tailored to their applications and the fluids they use. [Contents] ■ Bio-Clean Diaphragm Valves ■ Dead Space Countermeasure Products ■ Special Valves and Related Products ■ Sanitary Valves and Cleanroom Related Products ■ Technical Documentation *For more details, please refer to the PDF document or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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The latest published paper utilized Abby. This will be an online seminar featuring Associate Professor Yosuke Katsuta from the Graduate School of Advanced Science and Technology, Kumamoto University, who is also a co-founder of StapleBio. He is working on RNA hacking technology development aimed at altering the higher-order structure of target mRNA using short nucleic acids named Staple nucleic acids, with the goal of controlling gene expression. He will present the latest data focusing on the results of cell experiments and animal experiments in the development of this technology. Related paper on the lecture content: "Staple oligomers induce a stable RNA G-quadruplex structure for protein translation inhibition in therapeutics" | Nature Biomedical Engineering

[Speaker] Yoshirō Tsuruhara, Representative of Auto Insight Inc. / Technology Journalist and Editor [Key Lecture Content] The global automotive industry is undergoing significant upheaval. The term "CAST," which is bringing about even greater changes than the previously used keyword "CASE," is at the forefront. It stands for four elements: "China," which has begun to lead global automotive technology; "AI" (Artificial Intelligence), which is transforming the development process; "SDV" (Software Defined Vehicle), which is revolutionizing the creation of vehicle value; and "Trump," which is altering the rules of the world. What does the future of the automotive industry look like with CAST? [Lecture Items] 1. Current state of the automotive industry 2. The keyword "CAST" symbolizing transformation and its meaning 3. How China is dismantling the old order of the automotive industry 4. Generative AI infiltrating all development processes 5. How SDV is transforming "value creation" in the automotive industry 6. How the second Trump administration will change the rules of the global automotive industry 7. Changes in how the automotive industry generates revenue 8. Q&A

[Lecture Items] 1. Energy-saving Project for Data Centers National Research and Development Agency New Energy and Industrial Technology Development Organization Next Generation Green Data Center Technology Development Project Project Manager Toshiyuki Ando 1. About NEDO 2. Overview of the Next Generation Green Data Center Technology Development Project 3. Future of Data Centers 4. Elements Necessary for Energy Saving 5. Overview of Research and Development 6. Q&A / Business Card Exchange 2. Technology Trends of GaN Power Devices Expected to Contribute to Energy Saving in Data Centers and Other Industrial Applications Professor Noriyuki Iwamuro, Tsukuba University, Mathematical and Physical Sciences 1. Current and Future of the Power Device Market 2. Key Points in Power Device Development 3. Technologies Supporting the Latest Silicon MOSFETs 4. Why GaN Devices for Data Centers 5. Latest Technologies of GaN Power Devices 6. Differentiation Between GaN and SiC Power Devices 7. Q&A / Business Card Exchange

This is an announcement for a seminar hosted by our group company, Jemco Japan Management Co., Ltd. ■ Theme: "Mastering 'DX that Can Be Used on the Ground'! Business Reform in Management and Indirect Departments Utilizing DX" ■ Date and Time: November 12, 2025 (Wednesday) 14:00–15:00 ■ Format: ZOOM Webinar 【Seminar Content】 1. The 2030 Problem and Productivity Challenges in Management Departments 2. An Overview of Business Reform Utilizing Digital Technology 3. Automation of Routine Tasks with RPA (Power Automate) 4. Knowledge Search and Document Utilization with Generative AI × RAG 5. Implementation Examples of "Small-Scale DX" with Power Apps 6. Development of DX Talent and Internal Deployment Models If you wish to participate in the seminar, please apply using the URL below. (You will be redirected to the group company's site) *Please apply early as the registration will close once capacity is reached. https://www.jemco.co.jp/seminar/20251112dx/?lfpeid=kqbONicaYDDx&lfmaid=1000360919-5

At our booth, we will propose products that enable "improved production efficiency" and "cost reduction" through the stabilization of plastic molding. In particular, for recycled plastics, which have been gaining importance recently, the representatives of each device will explain the test results verified with demo machines conducted in-house. We will have a demo unit of the polymer moisture meter "AquaTrack V," and customers who bring samples will be able to conduct actual measurements. Larger samples, such as preforms, can also be measured as they are. *Please inquire in advance about the types of samples. Additionally, we will present a booklet titled "Dr. Plastic Molding's Rheology Lecture Notes," summarizing the understanding of material properties and predictions of viscosity and flowability, to those we speak with at the booth. We sincerely look forward to your visit. ◎ Exhibition Contents - Polymer moisture meter "AquaTrack V" (actual machine on display; demo measurements available) - Ultra-compact polymer dehumidifying dryer "Card Series" (full-size mock-up on display) - Capillary rheometer "R6000" (panel on display)