Heptapeptide AGP angiogenic peptide with vascular regeneration ability in addition to its effects.
AGP and related compounds = Applications in regenerative medicine and biomaterials Elucidation of angiogenesis mechanisms → Understanding of cancer proliferation and metastasis → Inhibition and antagonists
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basic information
**Advantages of Peptides** They have excellent safety and metabolic properties, are easy to design, and established methods for synthesis and testing. Amino acid derivatives serve as convenient building blocks for library construction, allowing for rapid structural optimization through solid-phase synthesis. Biomimetic biocompatible and biodegradable substances with DDS functions can serve as substitute tissues in humans, promising improved early healing and quality of life (QOL). ■ A new vascularization therapy that forms new blood vessels is expected for ischemic diseases caused by vascular occlusion, such as myocardial infarction and cerebral infarction. ■ Angiogenesis plays an important role in the regeneration and repair of organs using biomaterials such as artificial bones, as well as in the engraftment of biomaterials. ■ Relatively small peptides with angiogenic properties are non-toxic, easily metabolized, and can be administered alone or bound to biomaterials. ■ In regenerative medicine, rapid adhesion and angiogenesis are crucial for the quality of life after transplantation. ■ Biomimetic biocompatible and biodegradable substances with DDS functions can serve as substitute tissues in humans, promising improved early healing and quality of life (QOL).
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Applications/Examples of results
Currently planning clinical applications in clinical medicine and cell transplantation.
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Company information
The HiPep Research Institute was established to advance the development of new biochips using peptide arrays, the exploration and clinical application of novel active peptides, the application of peptides to biomaterials, and the development of synthetic vaccines, while providing consultation on research and development in the biomedical field, contract synthesis, analysis, testing, commissioned research, and the sale of equipment, instruments, and reagents related to compound library construction.
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