High-performance columns for HPLC, UHPLC, and UPLC [CORTECS]

Twenty years have passed since Waters launched the world's first ultra-high-performance liquid chromatograph (UPLC), and with the inclusion of <2.00> General Principles of Chromatography in the Japanese Pharmacopoeia, more people are becoming interested in speeding up LC analytical methods. On the other hand, we hear voices saying, "I understand the benefits, but it's difficult to adopt it for quality control methods in the current situation," and "I don't know what other applications there are besides adopting it for quality control methods." In this webinar, we will focus on the development of analytical methods among the various applications of high-speed and high-resolution analysis, explaining the transfer of analytical methods from UPLC to HPLC, points for column selection, and the differences between HPLC and UPLC systems.

In this seminar, we will introduce case studies of analytical method development using QbD software: Fusion, and present solutions that are helpful for developing robust analytical methods. ◆ Development of testing methods using the analytical method and method development software Fusion Dr. Taiki Kamiya, Kaken Pharmaceutical Co., Ltd. The analysis department of the CMC Center, to which the speaker belongs, has been developing testing methods using HPLC and introduced Fusion four years ago to improve operational efficiency. This time, we will explain the introduction environment, background, and overview of Fusion, and introduce the operational methods used in the department. Additionally, we will share impressions of using Fusion (advantages and challenges) as well as examples of testing method development (successes and failures). ◆ Waters Analytical Development Solutions, Waters Japan We will introduce mass spectrometers that can be used in conjunction with QbD software, LC systems that enable smooth development and transfer of analytical methods, and the quality of analytical columns, which is crucial for conducting robust analyses over the long term.

Waters provides numerous innovative technologies to leading companies in the global cosmetics and personal care products industry to improve the efficiency of inspections related to raw materials, ingredients, safety, and quality control. By leveraging our continuously advancing sample preparation products, columns, chromatography, mass spectrometry systems, and data management software, it becomes possible to shorten analysis time in analytical labs, enhance data quality, reduce costs, and comply with requirements in an ever-changing regulatory environment. - Ingredient composition ratios and safety verification in lotions, emulsions, and foundations - Evaluation of functional ingredients that provide high moisture retention and whitening effects - Assessment of container packaging degradation and concerns regarding leachables If you are facing challenges with the analyses mentioned above, please contact us.