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  6. Technical Data of Automatic Titration Device: Fundamentals of Non-Aqueous Titration

Technical Data of Automatic Titration Device: Fundamentals of Non-Aqueous Titration

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last updated:Nov 26, 2025

メトロームジャパン 本社
メトロームジャパン 本社
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Recommended for users of automatic titration devices struggling with non-aqueous titration! A beginner's booklet summarizing tips and applications for titration using organic solvents.

Table of Contents 1. When to perform non-aqueous titration? 2. Solvents used in non-aqueous titration 3. Applications 3-1. Measurement of the factor of perchloric acid c(HClO4) = 0.1 mol/L in glacial acetic acid 3-2. Measurement of the factor of c(KOH) = 0.1 mol/L in alcoholic solvents 3-3. Titration of nitric acid (mixed acid of HNO3/H2SO4) 3-4. Measurement of acid value of petrochemical products using KOH alcoholic solution 3-5. Measurement of hydrochloric acid ephedrine concentration according to European Pharmacopoeia 3-6. Measurement of hydrochloric acid ephedrine concentration according to USP24/25

    Fats and oilsAnalytical Equipment and DevicesElectrotitrator
非水滴定表紙_383X550.jpg

Technical Data of Automatic Titration Device: Fundamentals of Non-Aqueous Titration

非水滴定表紙_383X550.jpg
非水滴定表紙_383X550.jpg 非水滴定表紙_383X550.jpg EcoTitrator_withpeople2_4920_550X508pix.jpg omnis_4300_600X600.jpg
  • Metronome Automatic Titration Device Series
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basic information

Titration with non-aqueous solvents is primarily performed in the following cases: - When a substance is insoluble in water - When the sample is a fat or oil - When you want to quantitatively determine the components of a mixture of acids or bases individually through titration Instead of water, an appropriate organic solvent is used. The conditions are as follows: - The sample must dissolve in the organic solvent without reacting with it. - It should be possible to quantify the components in the mixture, preferably without using toxic substances or substances harmful to water quality. In most cases, a few types of solvents can suffice. Commonly used solvents include acetone, ethanol, isopropanol, methanol, toluene, and glacial acetic acid (concentrated acetic acid), and sometimes mixtures of these two-component solvents are used. The titrant is also not prepared with water. For example, ethanol solutions of NaOH, isopropanol solutions of KOH, ethanol solutions of HCl, and glacial acetic acid solutions of HClO4 are used. If acids or bases dissolve in a protic solvent (like H2O), protolysis occurs. However, the salts generated during titration can also cause protolytic decomposition. In such solvents, it is impossible to differentiate between strong acids of equivalent strength through titration.

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  • 916_naname_3388_424X550.jpg

    Automatic titration device 916, integrated and compliant with FDA Part 11.

  • omnis_4300_220X220pix_72dpi.jpg

    OMNIS robot system compatible, capable of simultaneous measurement of up to 5 samples.

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Titration Device Technical Data: Fundamentals of Non-Aqueous Titration

Titration Device Technical Data: Fundamentals of Non-Aqueous Titration

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Titration Device Technical Data: Non-aqueous Titration of Weak Bases with Perchloric Acid

Titration Device Technical Data: Non-aqueous Titration of Weak Bases with Perchloric Acid

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OMNIS Catalog for Automatic Potentiometric Titration Device 1 (Simultaneous Measurement of 5 Types of Titration)

OMNIS Catalog for Automatic Potentiometric Titration Device 1 (Simultaneous Measurement of 5 Types of Titration)

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Technical Data: Basics and Precautions of pH Glass Electrodes (A Must-Read for Beginners Using pH Meters and Titration Devices!)

Technical Data: Basics and Precautions of pH Glass Electrodes (A Must-Read for Beginners Using pH Meters and Titration Devices!)

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Basic Methods of Measuring Potential Difference: An Introductory Material to Solve the Question "What is a pH Electrode?"

Basic Methods of Measuring Potential Difference: An Introductory Material to Solve the Question "What is a pH Electrode?"

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Eco Titrator Automatic Potential Difference Titration Device Catalog

Eco Titrator Automatic Potential Difference Titration Device Catalog

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Automatic Titration Device / Karl Fischer Moisture Meter Tightland Series Catalog (3-Year Full Warranty!)

Automatic Titration Device / Karl Fischer Moisture Meter Tightland Series Catalog (3-Year Full Warranty!)

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Titration Device Technical Data - Introduction to Titration: What is Titration?

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Technical Data: Introduction to Ions, pH, and Dissociation Constants

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Technical Data for Titration Device: Measurement of Saponification Value of Edible Oils Using Automatic Titration Device

Technical Data for Titration Device: Measurement of Saponification Value of Edible Oils Using Automatic Titration Device

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Company information

メトロームジャパン

メトロームジャパン 本社

Testing, Analysis and Measurement

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Metrom AG, based in Herisau, Switzerland, is a leading company specializing in ion analysis with over 70 years of history. It provides products and services in more than 140 countries worldwide. Based on Swiss technology developed over many years, the equipment comes with a 3-year warranty.

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