New column for reverse phase separation of intact proteins and their subunits.
The analysis of proteins with high molecular weight and complex structures is accompanied by many difficulties. Waters has developed a new reversed-phase column based on the feedback and requests from researchers and analysts who are actually working on protein analysis. The BioResolve RP mAb Polyphenyl column uses solid core particles with a particle size of 2.7 μm and incorporates novel functional groups, achieving not only improved separation but also significant improvements in carryover compared to low molecular weight compounds. At the same time, it reduces issues commonly associated with high temperatures and ion-pair reagents used in reversed-phase separation of proteins. Additionally, we offer guard columns and standards specifically designed for protein analysis, along with comprehensive support such as user-friendly procedures and analysis examples for those conducting protein analysis for the first time.
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basic information
■ Usable with a wide range of LC systems from HPLC to UPLC ■ Superior separation of intact proteins and protein subunits ■ Reduction of carryover ■ Ability to use milder conditions – column temperature, ion pair reagent concentration ■ Increased sensitivity in LC-MS detection
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Company information
Waters Corporation, headquartered in Milford, Massachusetts, USA, has played a pioneering role as a specialized manufacturer of liquid chromatography since its establishment in 1958. Actively engaged in the development of new products and technologies, it has grown into an international group company that supplies not only high-performance liquid chromatography but also mass spectrometers (MS) and thermal analysis instruments. Waters Japan started operations in 1973 (Showa 48) as the Japanese base of Waters Corporation. Inheriting the corporate ethos of the U.S. headquarters, we have made "Customer Success" our mission and continue to provide innovative technologies and lab solutions.