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  3. Pharmaceutical and food related
  4. cell
  5. Human cells
  6. Completely new fresh human liver cells obtained from mice with human livers.

Completely new fresh human liver cells obtained from mice with human livers.

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last updated:Dec 19, 2022

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Using chimeric mice with human livers, known as "PXB mice," we can stably supply fresh and high-performance human liver cells.

We provide fresh human liver cells, "PXB-cells," isolated from the "PXB mouse," a chimeric mouse with a human liver. The fresh human liver cells, "PXB-cells," can maintain high human metabolic enzyme activity over a long period and can be used for drug metabolism, enzyme induction/inhibition, safety assessments, transporter evaluations, and anti-HBV drug efficacy evaluations in cell experiments. Please feel free to contact us if you have any requests. 【Features of "PXB-cells"】 ■ Stable supply of liver cells from the same donor (repeated experiments possible) ■ Long-term culture and maintenance of high human-type activity (over 3 weeks) ■ High cell adhesion (flat and spheroid culture possible) ■ Persistent infection with hepatitis virus (HBV) ■ In vitro and in vivo experiments possible with liver cells from the same donor *For more details, please download the PDF or feel free to contact us.

    Other bio-related products and servicesHuman cells
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Completely new fresh human liver cells obtained from mice with human livers.

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  • Related Link - https://phoenixbio.co.jp/products/pxb-cells.html

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【Cell Morphology of 'PXB-cells'】 ■ Excellent adhesion to culture dishes ■ Long-term culture is possible (cultivation record up to Day 100) *For more details, please download the PDF or feel free to contact us.

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Fresh human liver cells 'PXB-cells(R)'

Fresh human liver cells 'PXB-cells(R)'

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[Information] Fresh Human Liver Cells 'PXB-cells'

[Information] Fresh Human Liver Cells 'PXB-cells'

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Innovative technology 'PXB Mouse - PXB-cells'

Innovative technology 'PXB Mouse - PXB-cells'

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Our company offers contract testing services for drug development using PXB mice, which are high-quality human liver cell chimeric mice, as well as PXB mouse-related products. We have developed a technology that focuses on the function and proliferation ability of human liver cells, allowing them to proliferate in large quantities within experimental animals while maintaining their functionality. We are expanding a new business that provides the functions of human liver cells in a way that is easy to utilize for various applications.

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