ACQUITY APC Column

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basic information

◾Stable packing bed. The ACQUITY APC column eliminates shrinkage and swelling that often occur during solvent exchange with polymer stationary phases, providing a stable packing bed. ◾High efficiency. Optimized pore volume and particle size deliver unparalleled separation speed, separation capability, and chromatography efficiency. ◾Industry-leading reproducibility. Each step of column manufacturing is strictly controlled to provide exceptional product reliability.

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Applications/Examples of results

The ACQUITY APC column brand provides the tools necessary for the separation of the most complex polymer samples.

Detailed information

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  ■ BEH Technology Particles are manufactured through the ethylene bridge-type hybrid [BEH] synthesis, ensuring excellent column performance and long column life under stringent analytical conditions. These particles are synthesized using two types of high-purity monomers (tetraethoxysilane [TEOS] and bis(triethoxysilyl)ethane [BTEE]), resulting in very stable and mechanically strong particles.

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  ■ Rapid Solvent Exchange The rigid hybrid particles used in ACQUITY APC chromatography columns have an exceptional ability for rapid solvent exchange, allowing the same set of columns to be used under multiple conditions. Conventional polymer stationary phases are often used as dedicated columns for a single analytical condition due to the weakness of the chromatography bed against contraction and swelling. By eliminating this limitation, ACQUITY APC columns provide high performance that enables more freedom in method development and the characterization of diverse polymer samples.

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  ■ Outstanding Separation Performance The ACQUITY APC column is designed for polymer scientists who require high-separation polymer property analysis and column efficiency. The ACQUITY APC column introduces unprecedented new performance in terms of column efficiency, speed, and separation that is unlike traditional analytical methods. It enables the quantification and property analysis of polymer samples with reliability and accuracy while maximizing productivity. ■ High Reproducibility of Column Performance High reproducibility of column performance is one of the most important factors in achieving long-term analytical method reliability in polymer property analysis. Waters closely monitors and rigorously controls each step of the column manufacturing process to maintain unparalleled product reproducibility. From incoming material inspection to final batch testing, all tests are designed to ensure that the ACQUITY APC column consistently demonstrates the same performance across columns, batches, and over many years.

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  ■ ACQUITY APC Calibration Standard Kit The ACQUITY APC Calibration Standard is specially designed to match the molecular weight fraction range of the ACQUITY APC XT column. It allows for an appropriate number of data points to be obtained within the target molecular weight fraction range, eliminating the need to manually prepare a calibration standard mix. Furthermore, the ACQUITY APC system reduces calibration time to 1/3 to 1/5, enabling more frequent calibrations and improving the accuracy of results. In LC systems, due to sample pretreatment and variations in the laboratory environment, regular calibration is essential to achieve high accuracy in molecular weight determination. The ACQUITY APC standards include polystyrene and polymethyl methacrylate, providing standard kits for low, medium, and high molecular weight fraction ranges. Additionally, there is a lineup of method development kits that combine the three kits for low, medium, and high molecular weights to cover all molecular weight fraction ranges.