Mixed-mode chromatography resin that can be used for polishing purification after protein A chromatography.
"Cellufine MAX IB" is a new mixed-mode resin used for the polishing purification of monoclonal antibodies (Mab) after the purification of Protein A resin. It features surface modification with polyallylamine and the modification of some parts with butyl groups, allowing proteins to adsorb even at high salt concentrations. 【Features】 ■ Can be used for the polishing purification of antibody drugs ■ After Protein A purification, it can achieve high purity with just one purification step ■ Contributes to reduced lead times and cost savings through a two-step purification process ■ Stable resin that allows for in-place cleaning with 0.5M sodium hydroxide ■ Unique salt tolerance that retains proteins even at high salt concentrations *For more details, please refer to the PDF document or feel free to contact us.
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【Other Features】 Base resin: Highly cross-linked cellulose particles Average Diameter: Average 90 µm Ligand: Polyallylamine, partially modified with butyl groups Ion Exchange Capacity: > 80 μeq/mL Clean-in-Place (CIP): 0.5 M NaOH Sterilization: Autoclave at 121 °C, 20 min Recommended Cleaning Conditions: Ethanol (70%), Isopropanol (30%), Guanidine HCl (6M), Urea (6M) *For more details, please refer to the PDF document or feel free to contact us.*
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For more details, please refer to the PDF document or feel free to contact us.
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Our group was founded in 1906 as Sogi Electric Co., Ltd., and since then, we have been a pioneer in Japan's chemical industry, contributing to the development of society by expanding renewable energy generated by hydropower into the field of electrochemistry and developing domestic nitrogen fertilizers. Our unchanging mission is to engage in manufacturing that harmonizes with the global environment, to solve our customers' challenges in order to realize a rich life, and to cultivate outstanding human resources who can thrive globally, continuously serving society.