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  6. BioSMB Process 80 | 350 System

BioSMB Process 80 | 350 System

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last updated:Nov 06, 2025

Sartorius Stedim Japan K.K.
Sartorius Stedim Japan K.K.
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Single-use continuous production chromatography system, bioreactor process for perfusion and batch processes.

**Features** - Utilization of high-efficiency resin - High productivity - Overwhelming flexibility, capable of manifold installation within 30 minutes The BioSMB platform offers a highly flexible multi-column chromatography system. It achieves high throughput and efficient resin utilization compared to traditional batch and other continuous production chromatography. Flexible flow configurations are possible through a valve cassette composed of eight special single-use columns. *You can watch the webinar from the following URL:* https://bit.ly/3yaB65S *Title: 'Virtual Demonstration and Conceptual Overview of the BioSMB Multi-Column Chromatography Platform'*

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biosmb-single-use-b-0000836-white-sartorius-tif.jpg

BioSMB Process 80 | 350 System

biosmb-single-use-b-0000836-white-sartorius-tif.jpg
biosmb-single-use-b-0000836-white-sartorius-tif.jpg
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The BioSMB process system uses the principles of multi-column chromatography to enable manufacturers to efficiently utilize resins at clinical and commercial scales, significantly reducing resin costs. The BioSMB platform is the first market solution that allows for scale-up from process development to commercial production with single-use capabilities. These systems facilitate the direct replacement of a single chromatography unit operation within batch processes, providing an optimal entry point for process intensification downstream.

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BioSMB Process 80 System | BioSMB Process 350 System

BioSMB Process 80 System | BioSMB Process 350 System

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White Paper "Promoting Environmental Sustainability in the Biopharmaceutical Industry"

White Paper "Promoting Environmental Sustainability in the Biopharmaceutical Industry"

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[On-Demand Streaming Available] 10/6 (Wed) International Webinar 'Simplifying the mRNA Process_Part 2: Why Multi-Column Chromatography is Superior to Batch_Throughput Analysis'

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Participation in this webinar has ended. Those who wish to view it on demand can register for details and access it after registration. The mRNA vaccine plays a crucial role in combating SARS-CoV-2, and the necessity to produce mRNA has never been greater due to the ongoing development of treatments for various indications. In Part 2, the product manager and product specialist of the BioSMB system will explain how multi-column chromatography is superior to batch chromatography and how it can increase throughput by up to six times. They will also introduce traditional batch processes and demonstrate how BioSMB can be easily integrated into existing processes without compromising purification performance, throughput, or quality. [Topics] ▪ How batch chromatography limits throughput and increases resin costs ▪ How to improve throughput with less resin using BioSMB's multi-column cycling ▪ An analysis of how increased throughput reduces time to scale-up and the facility footprint.

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Sartorius

Sartorius Stedim Japan K.K.

Pharmaceuticals and Biotechnology

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Sartorius Stedim, established in 2007 through the merger of the German company Sartorius, founded in 1870, and the French company Stedim, is a pioneer in "Single-Use Technology (SUT)." As a company capable of providing comprehensive technical support to the pharmaceutical and biotechnology industries, its cutting-edge technology is highly regarded worldwide in the fields of scientific instruments and biotechnology.

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