Ideal for the purification of antibody drugs! Usable from lab to industrial scale. This is the Cellufine Protein A resin that achieves high flow rates and high adsorption.
"Cellufine SPA-HC" is a chromatography resin in which highly cross-linked spherical cellulose particles are immobilized with a highly alkaline-resistant Protein A ligand. It features excellent flow characteristics, low Protein A elution levels, and high dynamic binding capacity. Additionally, it maintains good adsorption activity even after multiple cycles of cleaning in place (CIP). This document provides a detailed explanation of "performance and features," including comparisons of dynamic binding capacity with various commercially available resin and comparisons of DBC for mAb and pAb, using diagrams and graphs. We encourage you to read it. [Contents (partial)] ■ Excellent dynamic binding capacity (DBC) ■ Comparison of adsorption amounts of monoclonal antibodies ■ Purification of monoclonal antibodies from CHO cell culture samples ■ High-throughput screening of elution pH ■ CIP stability of Cellufine SPA-HC *For more details, please refer to the PDF document or feel free to contact us.
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【Other Published Content】 ■ Carryover of CHO-HCP between cycles ■ Protein A elution amount in 0.1M NaOH CIP over 150 cycles ■ Flow rate characteristics at pilot scale (1-2L) ■ Purification steps after Cellufine SPA-HC ■ Recommendations for Clean In Place (CIP) ■ Order Information ■ Purchasing/Technical Support *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Our group was founded in 1906 as Sogi Electric Co., Ltd., and since then, we have been a pioneer in Japan's chemical industry, contributing to the development of society by expanding renewable energy generated by hydropower into the field of electrochemistry and developing domestic nitrogen fertilizers. Our unchanging mission is to engage in manufacturing that harmonizes with the global environment, to solve our customers' challenges in order to realize a rich life, and to cultivate outstanding human resources who can thrive globally, continuously serving society.
