"ESI and MALDI can be used without modification" - a groundbreaking ion source that enables imaging mass spectrometry in addition to conventional analysis.
The Spectroglyph MALDI/ESI injector is a groundbreaking ion source that enables imaging mass spectrometry in addition to conventional analysis when attached to a Thermo Fisher Scientific mass spectrometer. 【Features】 ◆ ESI and MALDI can be used without replacement The ESI ion source is connected orthogonally to the MALDI source, allowing for a change between ESI and MALDI simply by modifying the parameters within the device. ◆ Unique internal structure 1. Translation stage 2. Slide glass mount 3. High pressure ion funnel 4. Inlet capillary housing 5. Slide valve 6. Ion funnel trap 7. Beam expander 8. CCD camera The injector is equipped with a dual ion funnel, which prevents neutral substances from being introduced into the mass spectrometer, resulting in an improved S/N ratio for the samples. Additionally, by reducing the pressure within the chamber (to 6-7 torr), the ionization efficiency of the samples is also increased.
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basic information
Imaging mass spectrometry is a technique that directly ionizes biomolecules such as proteins from the surface of flat samples, like thinly sliced tissue sections, and measures them using a mass spectrometer. By performing two-dimensional imaging of the signal intensity of any detected ion, it is possible to visualize the distribution of substances on the sample surface. Therefore, by measuring the ions of drugs using mass spectrometry on tissue sections collected and prepared from individuals after drug administration, the distribution of the drug can be visualized, which is expected to be applied as a new tissue distribution testing method in pharmaceutical development. Additionally, a notable feature is that it can analyze the localization of multiple target substance groups from a single slice without the need for antibodies or staining agents in one measurement.
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Detailed information
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【Options】 ◆Innovative MALDI-2 Laser Source The Spectroglyph MALDI/ESI injector can be equipped with the MALDI-2 laser source as an option. MALDI-2 is a method that involves post-ionization by irradiating the plume of un-ionized material that has risen above the sample after MALDI laser irradiation with a laser of a different wavelength. This allows for the ionization of substances that were previously not ionized, or enhances the sensitivity of ionized samples.
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◆ITO Slide Glass A notch is made on one corner of the slide glass, allowing for easy identification of the ITO-coated surface.
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【KYA-ITO100】 Product Name: ITO glass, 0.7/100 Size: 25mm x 75mm Thickness: 0.7mm Quantity: 100 pieces per pack 【KYA-ITO50】 Product Name: ITO glass, 0.7/50 Size: 25mm x 75mm Thickness: 0.7mm Quantity: 50 pieces per pack
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◆ITO Slide Glass Holder It can hold 4 slide glasses. Both 25mm and 26mm widths are available.
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Product name: ITO glass holder Size: 25mm x 75mm Thickness: 0.7mm Quantity: 1 piece
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Company information
Our mission at Techno Alpha is to "shine a light on Japanese manufacturing" by creating overwhelming added value. To achieve this, we have set our vision as "the best technology trading company in Japan" and are committed to realizing it. Techno Alpha is a team composed of members with technical backgrounds, including sales, service, mechanical design, electrical design, and software development. Our strength lies in our ability to solve problems from the same perspective and in the same language as our customers, enabling us to provide rapid access to the latest technologies. In this team, we strive to discover cutting-edge technologies from around the world, introduce them domestically, and develop what does not yet exist in the market ourselves. By quickly uncovering the world's leading technologies and developing what is not available, we can support the entire manufacturing industry in Japan. Our team upholds the value of "connecting with the world, honing our technology, and challenging the future," and we will continue to refine our ability to discover products, design and develop, and provide technical services, all in pursuit of creating overwhelming added value that will impress our customers.
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