Social Defeat Stress Test SDS Mode

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last updated：Jul 18, 2025

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A mode for conducting social behavior tests based on social defeat stress widely used overseas.

The SDS (Social Defeat Stress) mode is a newly introduced mode in the behavior analysis device SCANET. It is a device used for social behavior testing based on social defeat stress, which is widely used overseas as a model experiment for depression. In the social defeat stress test, mice are cohabited in a cage with larger mice, which induces depression-related behaviors such as social avoidance (withdrawal) and anhedonia. The behavior of the mice is measured after they are subjected to stress from the larger mice. 【System Configuration】 ■ SCANET MV-40 (with SDS mode) ■ Software (with dedicated notebook PC) ■ Cage (assembly-type cage, SDS-specific cage) *For more details, please refer to the PDF materials or feel free to contact us.

Related Link - https://www.melquest.jp/products/products-343/

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【Image of the Experiment】 ■STEP 1: Stress the target mouse in a breeding cage - Place an aggressive and larger mouse in the same cage as the target mouse - Then, separate them with a transparent partition so they cannot make contact - Repeat this process for several days ■STEP 2: Analyze the behavior of the target mouse using SCANET - Set up an assembly cage in SCANET - Place the target mouse inside and start measuring - Next, install a dedicated enclosure with the aggressive mouse from STEP 1 - Measure the time spent by the target mouse in the interaction zone and corner zone - Compare the data before and after the installation of the dedicated enclosure *For more details, please refer to the PDF document or feel free to contact us.